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NLX-101 - 98%, high purity , CAS No.635323-95-4, Agonist of 5-HT 1A receptor
5-HT1 Selective Inhibitors | Agonists | Antagonists | Modulators
Basic Description Synonyms FT-0700595 | BDBM50476734 | 3-CHLORO-4-FLUOROPHENYL-(4-FLUORO-4-(((5-METHYLPYRIMIDIN-2-YLMETHYL)AMINO)METHYL)PIPERIDIN-1YL)METHANONE | BS-17356 | cyclohex-1-enyl boronic acid | UNII-83481Y1YCX | (3-chloro-4-fluorophenyl)-[4-fluoro-4-[[(5-methylpyrimidin-2 Specifications & Purity Moligand™, ≥98% Biochemical and Physiological Mechanisms NLX-101 (F-15599) is a highly selective 5-HT1A receptor biased agonist that mediates antidepressant-like activity in rats via prefrontal cortex 5-HT 1A receptors. Storage Temp Store at 2-8°C,Protected from light Shipped In Wet ice Grade Moligand™ Action Type AGONIST Mechanism of action Agonist of 5-HT 1A receptor Product Description Information
NLX-101 (F-15599) is a highly selective5-HT1A receptorbiased agonist that mediates antidepressant-like activity in rats via prefrontal cortex 5-HT 1A receptors.
Targets
5-HT1A receptor
Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers IUPAC Name (3-chloro-4-fluorophenyl)-[4-fluoro-4-[[(5-methylpyrimidin-2-yl)methylamino]methyl]piperidin-1-yl]methanone INCHI InChI=1S/C19H21ClF2N4O/c1-13-9-24-17(25-10-13)11-23-12-19(22)4-6-26(7-5-19)18(27)14-2-3-16(21)15(20)8-14/h2-3,8-10,23H,4-7,11-12H2,1H3 InChi Key WAAXKNFGOFTGLP-UHFFFAOYSA-N Canonical SMILES CC1=CN=C(N=C1)CNCC2(CCN(CC2)C(=O)C3=CC(=C(C=C3)F)Cl)F Isomeric SMILES CC1=CN=C(N=C1)CNCC2(CCN(CC2)C(=O)C3=CC(=C(C=C3)F)Cl)F PubChem CID 11741361 Molecular Weight 394.85
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