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N-(p-Toluoyl)glycine - >98.0%(HPLC), high purity , CAS No.27115-50-0

≥98%(HPLC)

CAS#: 27115-50-0
Molecular Weight: 193.2
MDL number: MFCD00020449
PubChem CID: 97479
PubChem SID: 488187059

Item Number

N159222

Grouped product items
SKU	Size	Availability	Price
N159222-1g	1g	4	$14.90
N159222-5g	5g	5	$56.90
N159222-25g	25g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$165.90
N159222-100g	100g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$595.90

View related series

carboxylic acid (0) Non heterocyclic block (0)

Basic Description

Synonyms	BBL025689 \| QXGDJXLJHBZELB-BDAKNGLRSA-N \| 4-METHYLHIPPURICACID \| Glycine, N-(4-methylbenzoyl)- \| [(4-Methylbenzoyl)amino]acetic acid # \| STK696186 \| DTXSID00181580 \| Sodium rabeprazole \| [(4-Methylbenzoyl)amino]acetic acid \| EINECS 248-231-8 \| F1130-0053
Specifications & Purity	≥98%(HPLC)
Shipped In	Normal
Product Description	4-Methylhippuric acid is the major metabolite of xylene and has been determined in urine by gas chromatography.

AI Insight

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Pubchem Sid	488187059
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488187059
IUPAC Name	2-[(4-methylbenzoyl)amino]acetic acid
INCHI	InChI=1S/C10H11NO3/c1-7-2-4-8(5-3-7)10(14)11-6-9(12)13/h2-5H,6H2,1H3,(H,11,14)(H,12,13)
InChi Key	NRSCPTLHWVWLLH-UHFFFAOYSA-N
Canonical SMILES	CC1=CC=C(C=C1)C(=O)NCC(=O)O
Isomeric SMILES	CC1=CC=C(C=C1)C(=O)NCC(=O)O
WGK Germany	3
PubChem CID	97479
Molecular Weight	193.2
Reaxy-Rn	2104083

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number	Certificate Type	Date	Item
D2323810	Certificate of Analysis	May 13, 2021	N159222
D2323818	Certificate of Analysis	May 13, 2021	N159222
L2404123	Certificate of Analysis	May 13, 2021	N159222

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
Reaxy-Rn	2104083

Reviews

References

1. P B Van Roosmalen,I Drummond. (1978-02-01) Simultaneous determination by gas chromatography of the major metabolites in urine of toluene, xylenes and styrene.. British journal of industrial medicine, 35 ((1)): (56-60). [PMID:629890]
2. R Tardif,J Brodeur,G L Plaa. (1989-11-01) Simultaneous high-performance liquid chromatographic analysis of hippuric acid and ortho-, meta-, and para-methylhippuric acids in urine.. Journal of analytical toxicology, 13 ((6)): (313-316). [PMID:2607759]
3. K Engström,V Riihimäki. (1988-01-01) Determination of methylhippuric acids in urine by gas chromatography.. IARC scientific publications, ((85)(85)): (313-318). [PMID:3182055]
4. M Buratti,G Caravelli,O Pellegrino,D Xaiz,C Valla,R Giampiccolo,A Colombi. (1988-11-01) [Determination of hippuric and methylhippuric acids with high pressure liquid chromatography: comparison between chromatographic and colorimetric methods].. La Medicina del lavoro, 79 ((6)): (489-499). [PMID:3246973]
5. Y Takeuchi,T Sakai,Y Ikeya,T Araki,K Ushio,S Yanagihara. (1986-11-01) [Improved high performance liquid chromatography determination of hippuric acid and methylhippuric acid isomers in urine].. Sangyo igaku. Japanese journal of industrial health, 28 ((6)): (455-461). [PMID:3586389]
6. M Ogata,T Taguchi. (1986-01-01) Quantitative analysis of urinary glycine conjugates by high performance liquid chromatography: excretion of hippuric acid and methylhippuric acids in the urine of subjects exposed to vapours of toluene and xylenes.. International archives of occupational and environmental health, 58 ((2)): (121-129). [PMID:3744566]
7. C Lacroix,F Inger,S Menager,O Lafont. (1986-10-31) [Simultaneous determination of urinary hippuric acid and o-, m-, p-methylhippuric acids with liquid chromatography].. Journal of chromatography, 382 (275-279). [PMID:3782394]
8. M Ogata. (1984-01-01) Estimation of solvent concentrations in ambient air from urinary metabolite levels of workers exposed to solvents.. Industrial health, 22 ((4)): (319-324). [PMID:6526705]
9. M Morin,P Chambon,R Chambon,N Bichet. (1981-06-05) Measurement of exposure to xylenes by separate determination of m- and p-methylhippuric acids in urine.. Journal of chromatography, 210 ((2)): (346-349). [PMID:7263793]
10. K J Lee,J J Lee,D C Moon. (1994-01-01) Application of micellar electrokinetic capillary chromatography for monitoring of hippuric and methylhippuric acid in human urine.. Electrophoresis, 15 ((1)): (98-102). [PMID:8143687]
11. O Inoue,K Seiji,T Suzuki,T Watanabe,H Nakatsuka,H Satoh,M Ikeda. (1991-08-01) Simultaneous determination of hippuric acid, o-, m-, and p-methylhippuric acid, phenylglyoxylic acid, and mandelic acid by HPLC.. Bulletin of environmental contamination and toxicology, 47 ((2)): (204-210). [PMID:1912696]
12. H Matsui,T Sekiya. (1989-11-10) High-performance liquid chromatographic separation of urinary hippuric and o-, m- and p-methylhippuric acids with a beta-cyclodextrin-bonded column.. Journal of chromatography, 496 ((1)): (189-193). [PMID:2592511]
13. M Ogata,T Taguchi. (1986-03-01) [Quantitative determination of urinary hippuric acid and o-, m- and p-methyl hippuric acids by high performance liquid chromatography].. Sangyo igaku. Japanese journal of industrial health, 28 ((2)): (120-121). [PMID:3761712]
14. O Inoue,K Seiji,T Kawai,T Watanabe,C Jin,S X Cai,Z Chen,Q S Qu,T Zhang,M Ikeda. (1993-01-01) Excretion of methylhippuric acids in urine of workers exposed to a xylene mixture: comparison among three xylene isomers and toluene.. International archives of occupational and environmental health, 64 ((7)): (533-539). [PMID:8482596]
15. C Burrini. (1999-03-05) [The simultaneous determination of hippuric acid, o-, m-, p-methylhippuric acids, mandelic acid and phenylglyoxylic acid in urine by HPLC].. La Medicina del lavoro, 89 ((5)): (404-411). [PMID:10064945]
16. T X Xiang,J Chen,B D Anderson. (2000-09-26) A quantitative model for the dependence of solute permeability on peptide and cholesterol content in biomembranes.. The Journal of membrane biology, 177 ((2)): (137-148). [PMID:11003688]
17. P Kongtip,J Vararussami,V Pruktharathikul. (2001-03-10) Modified method for determination of hippuric acid and methylhippuric acid in urine by gas chromatography.. Journal of chromatography. B, Biomedical sciences and applications, 751 ((1)): (199-203). [PMID:11232852]
18. Peter T Mayer,Bradley D Anderson. (2002-03-29) Transport across 1,9-decadiene precisely mimics the chemical selectivity of the barrier domain in egg lecithin bilayers.. Journal of pharmaceutical sciences, 91 ((3)): (640-646). [PMID:11920749]
19. Peter Terry Mayer,Tian-Xiang Xiang,Riku Niemi,Bradley D Anderson. (2003-02-13) A hydrophobicity scale for the lipid bilayer barrier domain from peptide permeabilities: nonadditivities in residue contributions.. Biochemistry, 42 ((6)): (1624-1636). [PMID:12578376]
20. Adriaan A S Marais,Johannes B Laurens. (2006-01-13) Analysis of urinary biomarkers for exposure to alkyl benzenes by isotope dilution gas chromatography-mass spectrometry.. Journal of separation science, 28 ((18)): (2526-2533). [PMID:16405184]
21. Marie Meyer-Monath,Claudine Chatellier,Florence Rouget,Isabelle Morel,Francois Lestremau. (2014-11-10) Development of a multi-residue method in a fetal matrix: analysis of meconium.. Analytical and bioanalytical chemistry, 406 ((30)): (7785-7797). [PMID:25381610]
22. Marie Meyer-Monath,Claudine Chatellier,Deirdre Cabooter,Florence Rouget,Isabelle Morel,Francois Lestremau. (2015-04-13) Development of liquid chromatography methods coupled to mass spectrometry for the analysis of substances with a wide variety of polarity in meconium.. Talanta, 138 (231-239). [PMID:25863396]
23. Daniel B Lunn,Young J Yun,James W Jorgenson. (2017-11-22) Retention and effective diffusion of model metabolites on porous graphitic carbon.. Journal of chromatography. A, 1530 (112-119). [PMID:29157608]
24. Anthony R Horner,Rachael E Wilson,Stephen R Groskreutz,Bridget E Murray,Stephen G Weber. (2019-01-11) Evaluation of three temperature- and mobile phase-dependent retention models for reversed-phase liquid chromatographic retention and apparent retention enthalpy.. Journal of chromatography. A, 1589 (73-82). [PMID:30626503]
25. Samuel Bernardo-Bermejo,Elena Sánchez-López,María Castro-Puyana,Selma Benito,Francisco Javier Lucio-Cazaña,María Luisa Marina. (2019-03-18) An untargeted metabolomic strategy based on liquid chromatography-mass spectrometry to study high glucose-induced changes in HK-2 cells.. Journal of chromatography. A, 1596 (124-133). [PMID:30878178]
26. Gianfranco Frigerio,Rosa Mercadante,Laura Campo,Elisa Polledri,Luca Boniardi,Luca Olgiati,Pasquale Missineo,William J Nash,Warwick B Dunn,Silvia Fustinoni. (2020-05-08) Urinary biomonitoring of subjects with different smoking habits. Part II: an untargeted metabolomic approach and the comparison with the targeted measurement of mercapturic acids.. Toxicology letters, 329 (56-66). [PMID:32380120]
27. Hongxuan Kuang,Zhilin Li,Xuejing Lv,Peiqiong Wu,Jianhua Tan,Qiurong Wu,Yonghong Li,Wenhui Jiang,Qihua Pang,Yaru Wang,Ruifang Fan. (2021-01-08) Exposure to volatile organic compounds may be associated with oxidative DNA damage-mediated childhood asthma.. Ecotoxicology and environmental safety, 210 (111864-111864). [PMID:33412282]
28. I Lundberg,J Sollenberg. (1986-04-01) Correlation of xylene exposure and methyl hippuric acid excretion in urine among paint industry workers.. Scandinavian journal of work, environment & health, 12 ((2)): (149-153). [PMID:3726497]
29. T Sakai,Y Niinuma,S Yanagihara,K Ushio. (1983-08-12) Simultaneous determination of hippuric acid and o-, m- and p-methylhippuric acids in urine by high-performance liquid chromatography.. Journal of chromatography, 276 ((1)): (182-188). [PMID:6672011]
30. G Bieniek,T Wilczok. (1981-08-01) Thin-layer chromatography of hippuric and m-methylhippuric acid in urine after mixed exposure to toluene and xylene.. British journal of industrial medicine, 38 ((3)): (304-306). [PMID:7272246]
31. P T Mayer,T X Xiang,B D Anderson. (2001-12-14) Independence of substituent contributions to the transport of small molecule permeants in lipid bilayers.. AAPS pharmSci, 2 ((2)): (E14-E14). [PMID:11741230]
32. Joon Hyuk Suh,Hye Yeon Lee,Unyong Kim,Han Young Eom,Junghyun Kim,Hyun-Deok Cho,Sang Beom Han. (2015-10-27) Simultaneous determination of benzene, toluene, ethylbenzene, and xylene metabolites in human urine using electromembrane extraction combined with liquid chromatography and tandem mass spectrometry.. Journal of separation science, 38 ((24)): (4276-4285). [PMID:26500147]

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