Potent PPAR-α agonist (EC 50 = 120 nM). Anandamide analog. Binds to cannabinoid receptor GPR119. Shows anti-ischemic and neuroprotective effects in vivo. Orally active.
Storage Temp
Store at -20°C
Shipped In
Ice chest + Ice pads
Grade
Moligand™
Action Type
AGONIST
Mechanism of action
Agonist of GPR119;Agonist of GPR55;Agonist of Peroxisome proliferator-activated receptor-α
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description
Oleoylethanolamide (OEA) is an endogenous fatty acid ethanolamine.Small intestine cells, adipose tissues, neurons and astrocytes produces OEA.
1.Qin Yeyu, Xie Jing, Zheng Ruihe, Li Yuhang, Wang Haixia. (2022) Oleoylethanolamide as a New Therapeutic Strategy to Alleviate Doxorubicin-Induced Cardiotoxicity. Frontiers in Pharmacology, 13 [PMID:35517792][10.3389/fphar.2022.863322]
References
1.Qin Yeyu, Xie Jing, Zheng Ruihe, Li Yuhang, Wang Haixia. (2022) Oleoylethanolamide as a New Therapeutic Strategy to Alleviate Doxorubicin-Induced Cardiotoxicity. Frontiers in Pharmacology, 13 [PMID:35517792][10.3389/fphar.2022.863322]
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