n-dodecylphosphocholine - >99%, high purity

Item Number

N130416

Grouped product items
SKU	Size	Availability	Price	Qty
N130416-250mg	250mg	3	$285.90
N130416-1g	1g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$790.90

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Basic Description

Synonyms	DPC \| Fos-Choline-12 \| FOS12 \| FC-12 \| dodecyl 2-(trimethylammonio)ethyl phosphate \| dodecyl phosphocholine \| DDPPC \| M5CF6282DD \| dodecyl 2-(trimethylazaniumyl)ethyl phosphate \| 2-(Trimethylammonio)ethyl dodecyl phosphate
Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	n-dodecylphosphocholine in combination with 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is used for membrane-mimetic bicelle system for orientation based studies in membrane proteins. It provides a zwitterionic surface in the membrane micelle struc
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	Dodecylphosphocholine is a structural analog of lauroyl lysophosphatidylcholine that is more stable to hydrolytic degradation. Dodecylphosphocholine is often used as a detergent for membrane protein solubilization and purification.It has been shown to improve paracellular permeability of hydrophilic compounds by modulating the tight junctions. This may have implications on its use for oral or nasal drug delivery.

Names and Identifiers

Pubchem Sid	504759768
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504759768
IUPAC Name	dodecyl 2-(trimethylazaniumyl)ethyl phosphate
INCHI	InChI=1S/C17H38NO4P/c1-5-6-7-8-9-10-11-12-13-14-16-21-23(19,20)22-17-15-18(2,3)4/h5-17H2,1-4H3
InChi Key	QBHFVMDLPTZDOI-UHFFFAOYSA-N
Canonical SMILES	CCCCCCCCCCCCOP(=O)([O-])OCC[N+](C)(C)C
Isomeric SMILES	CCCCCCCCCCCCOP(=O)([O-])OCC[N+](C)(C)C
PubChem CID	644308
Molecular Weight	351.46

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

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7 results found

Lot Number	Certificate Type	Date	Item
L2423091	Certificate of Analysis	Dec 12, 2024	N130416
L2423092	Certificate of Analysis	Dec 12, 2024	N130416
G2429580	Certificate of Analysis	Jul 19, 2024	N130416
G2429581	Certificate of Analysis	Jul 19, 2024	N130416
H2423039	Certificate of Analysis	Jul 19, 2024	N130416
G2120212	Certificate of Analysis	May 10, 2023	N130416
G2120354	Certificate of Analysis	May 09, 2023	N130416

Citations of This Product

1. Xian Sun, Xiaochuan Zhang, Xiaohong Ren, Hongyu Sun, Li Wu, Caifen Wang, Xiaohui Ye, Peter York, Zhaobing Gao, Hualiang Jiang, Jiwen Zhang, Xianzhen Yin. (2021) Multiscale Co-reconstruction of Lung Architectures and Inhalable Materials Spatial Distribution. Advanced Science, 8 (8): (2003941). [PMID:33898181] [10.1002/advs.202003941]
2. Yan Xiong, Jie Chen, Ming Duan, Xiang Li, Jun Li, Can Zhang, Shenwen Fang, Rui Liu, Run Zhang. (2019) Insight into the Adsorption-Interaction Mechanism of Cr(VI) at the Silica Adsorbent Surface by Evanescent Wave Measurement. LANGMUIR, 35 (45): (14414–14427). [PMID:31607126] [10.1021/acs.langmuir.9b01556]
3. Shailendra Shakya, Yaping He, Xiaohong Ren, Tao Guo, Abi Maharjan, Ting Luo, Tingting Wang, Ramesh Dhakhwa, Balmukunda Regmi, Haiyan Li, Ruxandra Gref, Jiwen Zhang. (2019) Ultrafine Silver Nanoparticles Embedded in Cyclodextrin Metal-Organic Frameworks with GRGDS Functionalization to Promote Antibacterial and Wound Healing Application. Small, 15 (27): (1901065). [PMID:31069948] [10.1002/smll.201901065]
4. Yaping He, Jian Xu, Xian Sun, Xiaohong Ren, Abi Maharjan, Peter York, Yong Su, Haiyan Li, Jiwen Zhang. (2019) Cuboidal tethered cyclodextrin frameworks tailored for hemostasis and injured vessel targeting. Theranostics, 9 (9): ( 2489–2504). [PMID:31131049] [10.7150/thno.31159]

References

1. Xian Sun, Xiaochuan Zhang, Xiaohong Ren, Hongyu Sun, Li Wu, Caifen Wang, Xiaohui Ye, Peter York, Zhaobing Gao, Hualiang Jiang, Jiwen Zhang, Xianzhen Yin. (2021) Multiscale Co-reconstruction of Lung Architectures and Inhalable Materials Spatial Distribution. Advanced Science, 8 (8): (2003941). [PMID:33898181] [10.1002/advs.202003941]
2. Yan Xiong, Jie Chen, Ming Duan, Xiang Li, Jun Li, Can Zhang, Shenwen Fang, Rui Liu, Run Zhang. (2019) Insight into the Adsorption-Interaction Mechanism of Cr(VI) at the Silica Adsorbent Surface by Evanescent Wave Measurement. LANGMUIR, 35 (45): (14414–14427). [PMID:31607126] [10.1021/acs.langmuir.9b01556]
3. Shailendra Shakya, Yaping He, Xiaohong Ren, Tao Guo, Abi Maharjan, Ting Luo, Tingting Wang, Ramesh Dhakhwa, Balmukunda Regmi, Haiyan Li, Ruxandra Gref, Jiwen Zhang. (2019) Ultrafine Silver Nanoparticles Embedded in Cyclodextrin Metal-Organic Frameworks with GRGDS Functionalization to Promote Antibacterial and Wound Healing Application. Small, 15 (27): (1901065). [PMID:31069948] [10.1002/smll.201901065]
4. Yaping He, Jian Xu, Xian Sun, Xiaohong Ren, Abi Maharjan, Peter York, Yong Su, Haiyan Li, Jiwen Zhang. (2019) Cuboidal tethered cyclodextrin frameworks tailored for hemostasis and injured vessel targeting. Theranostics, 9 (9): ( 2489–2504). [PMID:31131049] [10.7150/thno.31159]

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Basic Description