N-Benzyl-N-bis(PEG3-t-butyl ester) is a PEG derivative that contains a benzyl group and two PEG3-t-butyl ester groups. The benzyl group acts as a protecting group for the amine and can be deprotected via hydrogenolysis. The t-butyl ester groups can be removed under acidic conditions. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.