N-[12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-phytosphingosine - >99%, high purity , CAS No.388566-94-7

Item Number

N130256

Grouped product items
SKU	Size	Availability	Price
N130256-50μg	50μg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$356.90
N130256-100μg	100μg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$575.90
N130256-250μg	250μg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,228.90

Basic Description

Synonyms	phytosphingosine \| 554-62-1 \| (2S,3S,4R)-2-aminooctadecane-1,3,4-triol \| 4-D-Hydroxysphinganine \| D-Ribo-phytosphingosine \| C18-Phytosphingosine \| DS-phytosphingosine \| (+)-D-ribo-Phytosphingosine \| 388566-94-7 \| UNII-GIN46U9Q2Q \| 1,3,4-Octadecanetriol, 2-amino-, (2S,3S,4R)-
Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	Phytosphingosine (PHS) is a sphingoid lipid molecule which is known to exhibit antimicrobial and anti-inflammatory action. PHS can has the ability to increase the production of keratinocyte differentiation marker proteins, such as transglutaminase 1 and i
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	product description： C12-NBD Phytosphingosine is a fluorescent derivative of the naturally occurring lipid compound, phytosphingosine which is localised in skin, kidney and intestines. Phytosphingosine is a ceramide molecule localized to the stratum corneum. application： C12-NBD phytosphingosine has been used as a substrate to assay ceramidase activity. C12-NBD Phytosphingosine has been used as a substrate in ceramidase activity assay to study enzyme activity.

Names and Identifiers

IUPAC Name	(2S,3S,4R)-2-aminooctadecane-1,3,4-triol
INCHI	InChI=1S/C18H39NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(21)18(22)16(19)15-20/h16-18,20-22H,2-15,19H2,1H3/t16-,17+,18-/m0/s1
InChi Key	AERBNCYCJBRYDG-KSZLIROESA-N
Canonical SMILES	CCCCCCCCCCCCCCC(C(C(CO)N)O)O
Isomeric SMILES	CCCCCCCCCCCCCC[C@H]([C@H]([C@H](CO)N)O)O
PubChem CID	122121
Molecular Weight	677.91

Safety and Hazards(GHS)

Pictogram(s)	GHS09, GHS05
Signal	Danger
Hazard Statements	H318:Causes serious eye damage H400:Very toxic to aquatic life H410:Very toxic to aquatic life with long lasting effects
Precautionary Statements	P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P501:Dispose of contents/container to ... P391:Collect spillage. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P317:Get emergency medical help.

Citations of This Product

1. Yang Zhang, Xiaowen Liu, Guojing Yu, Hongzhe Gui, Jingteng Chi, Shuhan Liu, Liang Fang, Mingzhe Liu. (2023) Innovative insight into the mechanism of enantioselective skin permeation for chiral drugs. Expert Opinion on Drug Delivery, (25): [PMID:38112192] [10.1080/17425247.2023.2294877]

References

1. Yang Zhang, Xiaowen Liu, Guojing Yu, Hongzhe Gui, Jingteng Chi, Shuhan Liu, Liang Fang, Mingzhe Liu. (2023) Innovative insight into the mechanism of enantioselective skin permeation for chiral drugs. Expert Opinion on Drug Delivery, (25): [PMID:38112192] [10.1080/17425247.2023.2294877]

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Basic Description