MS023 - 10mM in DMSO, high purity , CAS No.1831110-54-3, Inhibitor of coactivator associated arginine methyltransferase 1;Inhibitor of protein arginine methyltransferase 1;Inhibitor of protein arginine methyltransferase 3;Inhibitor of protein arginine methyltransferase 6;Inhibitor of protein arginine methyltran

Item Number
M422249
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SKUSizeAvailabilityPrice Qty
M422249-1ml
1ml
Available within 4-8 weeks(?)
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$304.90

Potent, selective, cell-active PRMT inhibitor.

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Basic Description

SynonymsN1-Methyl-N1-[[4-[4-(1-methylethoxy)phenyl]-1H-pyrrol-3-yl]methyl]-1,2-ethanediamine;N1-((4-(4-isopropoxyphenyl)-1H-pyrrol-3-yl)methyl)-N1-methylethane-1,2-diamine
Specifications & PurityMoligand™, 10mM in DMSO
Biochemical and Physiological MechanismsMS023 is a potent, selective, and cell-active Type I PRMT inhibitor. IC 50 values are 30 nM (PRMT1), 119 nM (PRMT3), 83 nM (PRMT4), 4 nM (PRMT6) and 5 nM (PRMT8). It potently reduces cellular levels of H4R3me2a in MCF7 and HEK293 cells by inhibiting PRMT1
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of coactivator associated arginine methyltransferase 1;Inhibitor of protein arginine methyltransferase 1;Inhibitor of protein arginine methyltransferase 3;Inhibitor of protein arginine methyltransferase 6;Inhibitor of protein arginine methyltran
Product Description

Shipped at 4°C. Store at -20°C.

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Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name N'-methyl-N'-[[4-(4-propan-2-yloxyphenyl)-1H-pyrrol-3-yl]methyl]ethane-1,2-diamine
INCHI InChI=1S/C17H25N3O/c1-13(2)21-16-6-4-14(5-7-16)17-11-19-10-15(17)12-20(3)9-8-18/h4-7,10-11,13,19H,8-9,12,18H2,1-3H3
InChi Key FMTVWAGUJRUAKE-UHFFFAOYSA-N
Canonical SMILES CC(C)OC1=CC=C(C=C1)C2=CNC=C2CN(C)CCN
Isomeric SMILES CC(C)OC1=CC=C(C=C1)C2=CNC=C2CN(C)CCN
PubChem CID 92136227
MeSH Entry Terms MS023 compound;N1-((4-(4-isopropoxyphenyl)-1H-pyrrol-3-yl)methyl)-N1-methylethane-1,2-diamine
Molecular Weight 287.4

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

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