| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| M424434-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $69.90 |
Succinate dehydrogenase inhibitor
| Synonyms | Methylmalonic acid | 516-05-2 | 2-Methylmalonic acid | 2-Methylpropanedioic acid | Isosuccinic acid | methylmalonate | Propanedioic acid, methyl- | 1,1-Ethanedicarboxylic acid | methylpropanedioic acid | Malonic acid, methyl- | METHYL MALONIC ACID | NSC 25201 | CHEBI:30860 | MFCD0 |
|---|---|
| Specifications & Purity | Moligand™, 10mM in DMSO |
| Biochemical and Physiological Mechanisms | Intracellularly produces malonate, a reversible succinate dehydrogenase inhibitor used to generate Huntington's disease models. Induces apoptotic cell death in striatal neurons. |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Grade | Moligand™ |
| Action Type | AGONIST |
| Mechanism of action | Agonist of succinate receptor |
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| IUPAC Name | 2-methylpropanedioic acid |
|---|---|
| INCHI | InChI=1S/C4H6O4/c1-2(3(5)6)4(7)8/h2H,1H3,(H,5,6)(H,7,8) |
| InChi Key | ZIYVHBGGAOATLY-UHFFFAOYSA-N |
| Canonical SMILES | CC(C(=O)O)C(=O)O |
| Isomeric SMILES | CC(C(=O)O)C(=O)O |
| WGK Germany | 3 |
| RTECS | OO1400000 |
| PubChem CID | 487 |
| Molecular Weight | 118.09 |
| Reaxy-Rn | 1756084 |
| Pictogram(s) | GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
| WGK Germany | 3 |
| RTECS | OO1400000 |
| Reaxy-Rn | 1756084 |
