Basic Description

Synonyms	L-Carnitin \| LEVOCARNITINE (EP MONOGRAPH) \| levocarnitine HCl \| MFCD00038747 \| L-(-)-Carnitine \| 3-carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium \| LEVOCARNITINE (USP-RS) \| (-)-L-Carnitine \| 1-Propanaminium, 3-carboxy-2-hydroxy-N,N,N-trimethyl-, hydrox
Specifications & Purity	Moligand™, analytical standard, ≥99%
Storage Temp	Room temperature
Shipped In	Normal
Grade	analytical standard, Moligand™

AI Insight

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Pubchem Sid	504752029
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504752029
IUPAC Name	(3R)-3-hydroxy-4-(trimethylazaniumyl)butanoate
INCHI	InChI=1S/C7H15NO3/c1-8(2,3)5-6(9)4-7(10)11/h6,9H,4-5H2,1-3H3/t6-/m1/s1
InChi Key	PHIQHXFUZVPYII-ZCFIWIBFSA-N
Canonical SMILES	C[N+](C)(C)C[C@H](O)CC([O-])=O
Isomeric SMILES	C[N+](C)(C)C[C@@H](CC(=O)[O-])O
WGK Germany	3
RTECS	BP2980000
PubChem CID	10917
Molecular Weight	161.2
Beilstein	4292315

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number	Certificate Type	Date	Item
H2405182	Certificate of Analysis	Jul 29, 2024	C105424
J2217271	Certificate of Analysis	Jul 08, 2024	C105424
H2112070	Certificate of Analysis	May 11, 2023	C105424

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation
Precautionary Statements	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P264:Wash hands [and …] thoroughly after handling. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help.
WGK Germany	3
RTECS	BP2980000
Merck Index	1849

Reviews

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Qi Guo, Yang Feng, Hongjie Song, Mingxia Sun, Zixuan Zhan, Yi Lv. (2023) New Perylene-Based Chemiluminescent Polymer Nanoparticles for Highly Selective Detection of the Superoxide Anion In Vivo. ANALYTICAL CHEMISTRY, 95 (40): (15102–15109). [PMID:37779257] [10.1021/acs.analchem.3c03233]
2. Lyu Jiaming, Shen Shengyuan, Chen Lin, Zhu Yiming, Zhuang Songlin. (2023) Frequency selective fingerprint sensor: the Terahertz unity platform for broadband chiral enantiomers multiplexed signals and narrowband molecular AIT enhancement. PhotoniX, 4 (1): (1-14). [PMID:18477474] [10.1186/s43074-023-00108-1]
3. Yaodong Yi, Hengbin Zhang, Mingyang Chen, Binxin Chen, Yingchun Chen, Ping Li, Hui Zhou, Zhiyuan Ma, Huidi Jiang. (2023) Inhibition of multiple uptake transporters in cardiomyocytes/mitochondria alleviates doxorubicin-induced cardiotoxicity. CHEMICO-BIOLOGICAL INTERACTIONS, 382 (110627). [PMID:37453608] [10.1016/j.cbi.2023.110627]
4. Yixuan Zheng, Weiwei Ning, Quanhua Wang, Xueling Wei, Xingyang Li, Meng Pan. (2023) Hierarchical ZSM-5 zeolite using amino acid as template: Avoiding phase separation and fabricating an ultra-small mesoporous structure. MICROPOROUS AND MESOPOROUS MATERIALS, 355 (112578). [PMID:] [10.1016/j.micromeso.2023.112578]
5. Xu Zhang, Xiaotong Wang, Rui Shi, Xiaoku Ran, Xiahong He, Deqiang Dou. (2023) Effective substances and mechanism of red ginseng on rats with spleen-deficiency syndrome based on the substance and energy metabolism as well as the “brain-gut” axis. JOURNAL OF ETHNOPHARMACOLOGY, 311 (116438). [PMID:37003398] [10.1016/j.jep.2023.116438]
6. Yang Yang, Cuiting Lin, Qiang Zheng, Leqi Zhang, Yongmei Li, Qinghua Huang, Ting Wu, Zean Zhao, Lu Li, Jian Luo, Yanqing Jiang, Qun Zhang, Xing Wang, Chenglai Xia, Jianxin Pang. (2023) L-carnitine attenuated hyperuricemia-associated left ventricular remodeling through ameliorating cardiomyocytic lipid deposition. Frontiers in Pharmacology, 14 (1016633). [PMID:36817129] [10.3389/fphar.2023.1016633]
7. Chenhui Gu, Xuewen Hu, Baixi Shan, Xiaojing Wu, Jun Chen. (2023) Targeted and non-targeted metabolomics uncovering the effects of Er-Miao-Wan formula on rats with hyperuricemia. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 226 (115246). [PMID:36731256] [10.1016/j.jpba.2023.115246]
8. Jing Nie, Jiabei Zhou, Yi Shen, Ruimiao Lin, Haihong Hu, Kui Zeng, Huichang Bi, Min Huang, Lushan Yu, Su Zeng, Jing Miao. (2023) Studies on the interaction of five triazole fungicides with human renal transporters in cells. TOXICOLOGY IN VITRO, 88 (105555). [PMID:36669674] [10.1016/j.tiv.2023.105555]
9. Weili Li, Haiyang Li, Lujuan Zheng, Jing Xia, Xiaoxuan Yang, Shuhan Men, Ye Yuan, Yuying Fan. (2023) Ginsenoside CK improves skeletal muscle insulin resistance by activating DRP1/PINK1-mediated mitophagy. Food & Function, 14 (2): (1024-1036). [PMID:36562271] [10.1039/D2FO02026B]
10. Min Liu, Simin Wang, Wentao Bi, David Da Yong Chen. (2023) Plant polysaccharide itself as hydrogen bond donor in a deep eutectic system-based mechanochemical extraction method. FOOD CHEMISTRY, 399 (133941). [PMID:36007445] [10.1016/j.foodchem.2022.133941]
11. Haizhi Zhang, Hongyuan Wu, Xinguang Qin, Ying Shen, Xinlin Wei, Gang Liu. (2022) Metalloporphyrin and gold nanoparticles modified hollow zeolite imidazole Framework-8 with excellent peroxidase like activity for quick colorimetric determination of choline in infant formula milk powder. FOOD CHEMISTRY, 384 (132552). [PMID:35231712] [10.1016/j.foodchem.2022.132552]
12. Zefang Wang, Yan Peng, Chengjun Shi, Liping Wang, Xiaohong Chen, Wanwan Wu, Xu Wu, Yiming Zhu, Jingchen Zhang, Guiliang Cheng, Songlin Zhuang. (2021) Qualitative and quantitative recognition of chiral drugs based on terahertz spectroscopy. ANALYST, 146 (12): (3888-3898). [PMID:34042921] [10.1039/D1AN00500F]
13. Yingchun Chen, Cui Li, Yaodong Yi, Weijuan Du, Huidi Jiang, Su Zeng, Hui Zhou. (2020) Organic Cation Transporter 1 and 3 Contribute to the High Accumulation of Dehydrocorydaline in the Heart. DRUG METABOLISM AND DISPOSITION, 48 (10): (1074-1083). [PMID:32723846] [10.1124/dmd.120.000025]
14. Jin-Ming Wang, Run Xu, Qian-Nan Di, Hao-Wei Fu, Qian Xu. (2020) Determination of urinary carnitine levels as a potential indicator of uterine fibroids caused by nonylphenol exposure. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 1152 (122248). [PMID:32590215] [10.1016/j.jchromb.2020.122248]
15. Longfa Kou, Rui Sun, Shuyi Xiao, Xiao Cui, Jin Sun, Vadivel Ganapathy, Qing Yao, Ruijie Chen. (2020) OCTN2-targeted nanoparticles for oral delivery of paclitaxel: differential impact of the polyethylene glycol linker size on drug delivery in vitro, in situ, and in vivo. DRUG DELIVERY, [PMID:31913724] [10.1080/10717544.2019.1710623]
16. Qingquan Zeng, Mengru Bai, Cui Li, Shuanghui Lu, Zhiyuan Ma, Yunchun Zhao, Hui Zhou, Huidi Jiang, Dongli Sun, Caihong Zheng. (2019) Multiple Drug Transporters Contribute to the Placental Transfer of Emtricitabine. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, [PMID:31160284] [10.1128/AAC.00199-19]
17. Xueying Liu, Xiaoku Ran, Muhammad Riaz, Haixue Kuang, Deqiang Dou, Decheng Cai. (2019) Mechanism Investigation of Tagetes patula L. against Chronic Nonbacterial Prostatitis by Metabolomics and Network Pharmacology. MOLECULES, 24 (12): (2266). [PMID:31216740] [10.3390/molecules24122266]
18. Dong-Liang Lu, Samwel Mchele Limbu, Hong-Bo Lv, Qiang Ma, Li-Qiao Chen, Mei-Ling Zhang, Zhen-Yu Du. (2019) The comparisons in protective mechanisms and efficiencies among dietary α-lipoic acid, β-glucan and l-carnitine on Nile tilapia infected by Aeromonas hydrophila. FISH & SHELLFISH IMMUNOLOGY, 86 (785). [PMID:30553889] [10.1016/j.fsi.2018.12.023]
19. Liping Li, Yayun Weng, Wei Wang, Mengru Bai, Hongmei Lei, Hui Zhou, Huidi Jiang. (2017) Multiple organic cation transporters contribute to the renal transport of sulpiride. BIOPHARMACEUTICS & DRUG DISPOSITION, 38 (9): (526-534). [PMID:28926871] [10.1002/bdd.2104]
20. Tao Wu, Anqi Guo, Qingyu Shu, Yangjian Qi, Ying Kong, Zhiping Sun, Shumin Sun, Zhengwei Fu. (2015) l-Carnitine intake prevents irregular feeding-induced obesity and lipid metabolism disorder. GENE, 554 (148). [PMID:25445284] [10.1016/j.gene.2014.10.040]
21. Suo Decheng, Li Lan, Zhang Su, Su Xiaoou. (2012) Simultaneous determination of choline, carnitine and betaine in premixes by non-suppressed ion chromatography. Analytical Methods, 5 (1): (59-63). [PMID:] [10.1039/C2AY25955A]

References

1. Qi Guo, Yang Feng, Hongjie Song, Mingxia Sun, Zixuan Zhan, Yi Lv. (2023) New Perylene-Based Chemiluminescent Polymer Nanoparticles for Highly Selective Detection of the Superoxide Anion In Vivo. ANALYTICAL CHEMISTRY, 95 (40): (15102–15109). [PMID:37779257] [10.1021/acs.analchem.3c03233]
2. Lyu Jiaming, Shen Shengyuan, Chen Lin, Zhu Yiming, Zhuang Songlin. (2023) Frequency selective fingerprint sensor: the Terahertz unity platform for broadband chiral enantiomers multiplexed signals and narrowband molecular AIT enhancement. PhotoniX, 4 (1): (1-14). [PMID:18477474] [10.1186/s43074-023-00108-1]
3. Yaodong Yi, Hengbin Zhang, Mingyang Chen, Binxin Chen, Yingchun Chen, Ping Li, Hui Zhou, Zhiyuan Ma, Huidi Jiang. (2023) Inhibition of multiple uptake transporters in cardiomyocytes/mitochondria alleviates doxorubicin-induced cardiotoxicity. CHEMICO-BIOLOGICAL INTERACTIONS, 382 (110627). [PMID:37453608] [10.1016/j.cbi.2023.110627]
4. Yixuan Zheng, Weiwei Ning, Quanhua Wang, Xueling Wei, Xingyang Li, Meng Pan. (2023) Hierarchical ZSM-5 zeolite using amino acid as template: Avoiding phase separation and fabricating an ultra-small mesoporous structure. MICROPOROUS AND MESOPOROUS MATERIALS, 355 (112578). [PMID:] [10.1016/j.micromeso.2023.112578]
5. Xu Zhang, Xiaotong Wang, Rui Shi, Xiaoku Ran, Xiahong He, Deqiang Dou. (2023) Effective substances and mechanism of red ginseng on rats with spleen-deficiency syndrome based on the substance and energy metabolism as well as the “brain-gut” axis. JOURNAL OF ETHNOPHARMACOLOGY, 311 (116438). [PMID:37003398] [10.1016/j.jep.2023.116438]
6. Yang Yang, Cuiting Lin, Qiang Zheng, Leqi Zhang, Yongmei Li, Qinghua Huang, Ting Wu, Zean Zhao, Lu Li, Jian Luo, Yanqing Jiang, Qun Zhang, Xing Wang, Chenglai Xia, Jianxin Pang. (2023) L-carnitine attenuated hyperuricemia-associated left ventricular remodeling through ameliorating cardiomyocytic lipid deposition. Frontiers in Pharmacology, 14 (1016633). [PMID:36817129] [10.3389/fphar.2023.1016633]
7. Chenhui Gu, Xuewen Hu, Baixi Shan, Xiaojing Wu, Jun Chen. (2023) Targeted and non-targeted metabolomics uncovering the effects of Er-Miao-Wan formula on rats with hyperuricemia. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 226 (115246). [PMID:36731256] [10.1016/j.jpba.2023.115246]
8. Jing Nie, Jiabei Zhou, Yi Shen, Ruimiao Lin, Haihong Hu, Kui Zeng, Huichang Bi, Min Huang, Lushan Yu, Su Zeng, Jing Miao. (2023) Studies on the interaction of five triazole fungicides with human renal transporters in cells. TOXICOLOGY IN VITRO, 88 (105555). [PMID:36669674] [10.1016/j.tiv.2023.105555]
9. Weili Li, Haiyang Li, Lujuan Zheng, Jing Xia, Xiaoxuan Yang, Shuhan Men, Ye Yuan, Yuying Fan. (2023) Ginsenoside CK improves skeletal muscle insulin resistance by activating DRP1/PINK1-mediated mitophagy. Food & Function, 14 (2): (1024-1036). [PMID:36562271] [10.1039/D2FO02026B]
10. Min Liu, Simin Wang, Wentao Bi, David Da Yong Chen. (2023) Plant polysaccharide itself as hydrogen bond donor in a deep eutectic system-based mechanochemical extraction method. FOOD CHEMISTRY, 399 (133941). [PMID:36007445] [10.1016/j.foodchem.2022.133941]
11. Haizhi Zhang, Hongyuan Wu, Xinguang Qin, Ying Shen, Xinlin Wei, Gang Liu. (2022) Metalloporphyrin and gold nanoparticles modified hollow zeolite imidazole Framework-8 with excellent peroxidase like activity for quick colorimetric determination of choline in infant formula milk powder. FOOD CHEMISTRY, 384 (132552). [PMID:35231712] [10.1016/j.foodchem.2022.132552]
12. Zefang Wang, Yan Peng, Chengjun Shi, Liping Wang, Xiaohong Chen, Wanwan Wu, Xu Wu, Yiming Zhu, Jingchen Zhang, Guiliang Cheng, Songlin Zhuang. (2021) Qualitative and quantitative recognition of chiral drugs based on terahertz spectroscopy. ANALYST, 146 (12): (3888-3898). [PMID:34042921] [10.1039/D1AN00500F]
13. Yingchun Chen, Cui Li, Yaodong Yi, Weijuan Du, Huidi Jiang, Su Zeng, Hui Zhou. (2020) Organic Cation Transporter 1 and 3 Contribute to the High Accumulation of Dehydrocorydaline in the Heart. DRUG METABOLISM AND DISPOSITION, 48 (10): (1074-1083). [PMID:32723846] [10.1124/dmd.120.000025]
14. Jin-Ming Wang, Run Xu, Qian-Nan Di, Hao-Wei Fu, Qian Xu. (2020) Determination of urinary carnitine levels as a potential indicator of uterine fibroids caused by nonylphenol exposure. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 1152 (122248). [PMID:32590215] [10.1016/j.jchromb.2020.122248]
15. Longfa Kou, Rui Sun, Shuyi Xiao, Xiao Cui, Jin Sun, Vadivel Ganapathy, Qing Yao, Ruijie Chen. (2020) OCTN2-targeted nanoparticles for oral delivery of paclitaxel: differential impact of the polyethylene glycol linker size on drug delivery in vitro, in situ, and in vivo. DRUG DELIVERY, [PMID:31913724] [10.1080/10717544.2019.1710623]
16. Qingquan Zeng, Mengru Bai, Cui Li, Shuanghui Lu, Zhiyuan Ma, Yunchun Zhao, Hui Zhou, Huidi Jiang, Dongli Sun, Caihong Zheng. (2019) Multiple Drug Transporters Contribute to the Placental Transfer of Emtricitabine. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, [PMID:31160284] [10.1128/AAC.00199-19]
17. Xueying Liu, Xiaoku Ran, Muhammad Riaz, Haixue Kuang, Deqiang Dou, Decheng Cai. (2019) Mechanism Investigation of Tagetes patula L. against Chronic Nonbacterial Prostatitis by Metabolomics and Network Pharmacology. MOLECULES, 24 (12): (2266). [PMID:31216740] [10.3390/molecules24122266]
18. Dong-Liang Lu, Samwel Mchele Limbu, Hong-Bo Lv, Qiang Ma, Li-Qiao Chen, Mei-Ling Zhang, Zhen-Yu Du. (2019) The comparisons in protective mechanisms and efficiencies among dietary α-lipoic acid, β-glucan and l-carnitine on Nile tilapia infected by Aeromonas hydrophila. FISH & SHELLFISH IMMUNOLOGY, 86 (785). [PMID:30553889] [10.1016/j.fsi.2018.12.023]
19. Liping Li, Yayun Weng, Wei Wang, Mengru Bai, Hongmei Lei, Hui Zhou, Huidi Jiang. (2017) Multiple organic cation transporters contribute to the renal transport of sulpiride. BIOPHARMACEUTICS & DRUG DISPOSITION, 38 (9): (526-534). [PMID:28926871] [10.1002/bdd.2104]
20. Tao Wu, Anqi Guo, Qingyu Shu, Yangjian Qi, Ying Kong, Zhiping Sun, Shumin Sun, Zhengwei Fu. (2015) l-Carnitine intake prevents irregular feeding-induced obesity and lipid metabolism disorder. GENE, 554 (148). [PMID:25445284] [10.1016/j.gene.2014.10.040]
21. Suo Decheng, Li Lan, Zhang Su, Su Xiaoou. (2012) Simultaneous determination of choline, carnitine and betaine in premixes by non-suppressed ion chromatography. Analytical Methods, 5 (1): (59-63). [PMID:] [10.1039/C2AY25955A]

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L(-)-Carnitine - analytical standard，99%, high purity , CAS No.541-15-1