Basic Description

Synonyms	L-Carnitin \| LEVOCARNITINE (EP MONOGRAPH) \| levocarnitine HCl \| MFCD00038747 \| L-(-)-Carnitine \| 3-carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium \| LEVOCARNITINE (USP-RS) \| (-)-L-Carnitine \| 1-Propanaminium, 3-carboxy-2-hydroxy-N,N,N-trimethyl-, hydrox
Specifications & Purity	Moligand™, ≥98%
Biochemical and Physiological Mechanisms	Carnitine biosynthesized from lysine. Carnitine facilitates fatty acid transport into the mitochondrial compartment. In skeletal and cardiac muscle tissue it acts as a metabolic cofactor. Carnitine might be associated with the energy production from branc
Storage Temp	Argon charged
Shipped In	Normal
Grade	Moligand™
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	L-Carnitine ((R)-Carnitine), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine is an antioxidant. L-Carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism

AI Insight

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Pubchem Sid	488181224
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488181224
IUPAC Name	(3R)-3-hydroxy-4-(trimethylazaniumyl)butanoate
INCHI	InChI=1S/C7H15NO3/c1-8(2,3)5-6(9)4-7(10)11/h6,9H,4-5H2,1-3H3/t6-/m1/s1
InChi Key	PHIQHXFUZVPYII-ZCFIWIBFSA-N
Canonical SMILES	C[N+](C)(C)C[C@H](O)CC([O-])=O
Isomeric SMILES	C[N+](C)(C)C[C@@H](CC(=O)[O-])O
WGK Germany	3
RTECS	BP2980000
PubChem CID	10917
Molecular Weight	161.2
Beilstein	4292315

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

44 results found

Lot Number	Certificate Type	Date	Item
A2521097	Certificate of Analysis	Dec 30, 2024	C105423
A2521100	Certificate of Analysis	Dec 30, 2024	C105423
A2521094	Certificate of Analysis	Dec 30, 2024	C105423
K2420646	Certificate of Analysis	Nov 11, 2024	C105423
K2420379	Certificate of Analysis	Nov 11, 2024	C105423
K2420378	Certificate of Analysis	Nov 11, 2024	C105423
K2420377	Certificate of Analysis	Nov 11, 2024	C105423
K2420376	Certificate of Analysis	Nov 11, 2024	C105423
K2418091	Certificate of Analysis	Nov 11, 2024	C105423
K2418090	Certificate of Analysis	Nov 11, 2024	C105423
K2418089	Certificate of Analysis	Nov 11, 2024	C105423
J2425374	Certificate of Analysis	Oct 19, 2024	C105423
J2425373	Certificate of Analysis	Oct 19, 2024	C105423
I2413270	Certificate of Analysis	Aug 31, 2024	C105423
I2413271	Certificate of Analysis	Aug 31, 2024	C105423
I2413272	Certificate of Analysis	Aug 31, 2024	C105423
I2413273	Certificate of Analysis	Aug 31, 2024	C105423
I2413275	Certificate of Analysis	Aug 31, 2024	C105423
I2413274	Certificate of Analysis	Aug 31, 2024	C105423
F2415199	Certificate of Analysis	May 31, 2024	C105423
F2415202	Certificate of Analysis	May 31, 2024	C105423
F2415240	Certificate of Analysis	May 31, 2024	C105423
E2408117	Certificate of Analysis	Apr 28, 2024	C105423
D2425238	Certificate of Analysis	Mar 25, 2024	C105423
B2321846	Certificate of Analysis	Nov 10, 2022	C105423
B2321867	Certificate of Analysis	Nov 10, 2022	C105423
B2321836	Certificate of Analysis	Nov 10, 2022	C105423
B2321824	Certificate of Analysis	Nov 10, 2022	C105423
B2321775	Certificate of Analysis	Nov 10, 2022	C105423
I2403072	Certificate of Analysis	Nov 10, 2022	C105423
C2414040	Certificate of Analysis	Nov 10, 2022	C105423
I2215145	Certificate of Analysis	Sep 03, 2022	C105423
I2215144	Certificate of Analysis	Sep 03, 2022	C105423
I2215143	Certificate of Analysis	Sep 03, 2022	C105423
I2215063	Certificate of Analysis	Sep 03, 2022	C105423
G2307579	Certificate of Analysis	Sep 03, 2022	C105423
H2223246	Certificate of Analysis	Jul 21, 2022	C105423
H2223244	Certificate of Analysis	Jul 21, 2022	C105423
C1812008	Certificate of Analysis	Jan 21, 2022	C105423
C1812007	Certificate of Analysis	Jan 21, 2022	C105423
B2222401	Certificate of Analysis	Dec 20, 2021	C105423
B2222376	Certificate of Analysis	Dec 20, 2021	C105423
B2222364	Certificate of Analysis	Dec 20, 2021	C105423
B2222363	Certificate of Analysis	Dec 20, 2021	C105423

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Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation
Precautionary Statements	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P264:Wash hands [and …] thoroughly after handling. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help.
WGK Germany	3
RTECS	BP2980000
Merck Index	1849

Reviews

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Qi Guo, Yang Feng, Hongjie Song, Mingxia Sun, Zixuan Zhan, Yi Lv. (2023) New Perylene-Based Chemiluminescent Polymer Nanoparticles for Highly Selective Detection of the Superoxide Anion In Vivo. ANALYTICAL CHEMISTRY, 95 (40): (15102–15109). [PMID:37779257] [10.1021/acs.analchem.3c03233]
2. Lyu Jiaming, Shen Shengyuan, Chen Lin, Zhu Yiming, Zhuang Songlin. (2023) Frequency selective fingerprint sensor: the Terahertz unity platform for broadband chiral enantiomers multiplexed signals and narrowband molecular AIT enhancement. PhotoniX, 4 (1): (1-14). [PMID:18477474] [10.1186/s43074-023-00108-1]
3. Yaodong Yi, Hengbin Zhang, Mingyang Chen, Binxin Chen, Yingchun Chen, Ping Li, Hui Zhou, Zhiyuan Ma, Huidi Jiang. (2023) Inhibition of multiple uptake transporters in cardiomyocytes/mitochondria alleviates doxorubicin-induced cardiotoxicity. CHEMICO-BIOLOGICAL INTERACTIONS, 382 (110627). [PMID:37453608] [10.1016/j.cbi.2023.110627]
4. Yixuan Zheng, Weiwei Ning, Quanhua Wang, Xueling Wei, Xingyang Li, Meng Pan. (2023) Hierarchical ZSM-5 zeolite using amino acid as template: Avoiding phase separation and fabricating an ultra-small mesoporous structure. MICROPOROUS AND MESOPOROUS MATERIALS, 355 (112578). [PMID:] [10.1016/j.micromeso.2023.112578]
5. Xu Zhang, Xiaotong Wang, Rui Shi, Xiaoku Ran, Xiahong He, Deqiang Dou. (2023) Effective substances and mechanism of red ginseng on rats with spleen-deficiency syndrome based on the substance and energy metabolism as well as the “brain-gut” axis. JOURNAL OF ETHNOPHARMACOLOGY, 311 (116438). [PMID:37003398] [10.1016/j.jep.2023.116438]
6. Yang Yang, Cuiting Lin, Qiang Zheng, Leqi Zhang, Yongmei Li, Qinghua Huang, Ting Wu, Zean Zhao, Lu Li, Jian Luo, Yanqing Jiang, Qun Zhang, Xing Wang, Chenglai Xia, Jianxin Pang. (2023) L-carnitine attenuated hyperuricemia-associated left ventricular remodeling through ameliorating cardiomyocytic lipid deposition. Frontiers in Pharmacology, 14 (1016633). [PMID:36817129] [10.3389/fphar.2023.1016633]
7. Chenhui Gu, Xuewen Hu, Baixi Shan, Xiaojing Wu, Jun Chen. (2023) Targeted and non-targeted metabolomics uncovering the effects of Er-Miao-Wan formula on rats with hyperuricemia. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 226 (115246). [PMID:36731256] [10.1016/j.jpba.2023.115246]
8. Jing Nie, Jiabei Zhou, Yi Shen, Ruimiao Lin, Haihong Hu, Kui Zeng, Huichang Bi, Min Huang, Lushan Yu, Su Zeng, Jing Miao. (2023) Studies on the interaction of five triazole fungicides with human renal transporters in cells. TOXICOLOGY IN VITRO, 88 (105555). [PMID:36669674] [10.1016/j.tiv.2023.105555]
9. Weili Li, Haiyang Li, Lujuan Zheng, Jing Xia, Xiaoxuan Yang, Shuhan Men, Ye Yuan, Yuying Fan. (2023) Ginsenoside CK improves skeletal muscle insulin resistance by activating DRP1/PINK1-mediated mitophagy. Food & Function, 14 (2): (1024-1036). [PMID:36562271] [10.1039/D2FO02026B]
10. Min Liu, Simin Wang, Wentao Bi, David Da Yong Chen. (2023) Plant polysaccharide itself as hydrogen bond donor in a deep eutectic system-based mechanochemical extraction method. FOOD CHEMISTRY, 399 (133941). [PMID:36007445] [10.1016/j.foodchem.2022.133941]
11. Haizhi Zhang, Hongyuan Wu, Xinguang Qin, Ying Shen, Xinlin Wei, Gang Liu. (2022) Metalloporphyrin and gold nanoparticles modified hollow zeolite imidazole Framework-8 with excellent peroxidase like activity for quick colorimetric determination of choline in infant formula milk powder. FOOD CHEMISTRY, 384 (132552). [PMID:35231712] [10.1016/j.foodchem.2022.132552]
12. Zefang Wang, Yan Peng, Chengjun Shi, Liping Wang, Xiaohong Chen, Wanwan Wu, Xu Wu, Yiming Zhu, Jingchen Zhang, Guiliang Cheng, Songlin Zhuang. (2021) Qualitative and quantitative recognition of chiral drugs based on terahertz spectroscopy. ANALYST, 146 (12): (3888-3898). [PMID:34042921] [10.1039/D1AN00500F]
13. Yingchun Chen, Cui Li, Yaodong Yi, Weijuan Du, Huidi Jiang, Su Zeng, Hui Zhou. (2020) Organic Cation Transporter 1 and 3 Contribute to the High Accumulation of Dehydrocorydaline in the Heart. DRUG METABOLISM AND DISPOSITION, 48 (10): (1074-1083). [PMID:32723846] [10.1124/dmd.120.000025]
14. Jin-Ming Wang, Run Xu, Qian-Nan Di, Hao-Wei Fu, Qian Xu. (2020) Determination of urinary carnitine levels as a potential indicator of uterine fibroids caused by nonylphenol exposure. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 1152 (122248). [PMID:32590215] [10.1016/j.jchromb.2020.122248]
15. Longfa Kou, Rui Sun, Shuyi Xiao, Xiao Cui, Jin Sun, Vadivel Ganapathy, Qing Yao, Ruijie Chen. (2020) OCTN2-targeted nanoparticles for oral delivery of paclitaxel: differential impact of the polyethylene glycol linker size on drug delivery in vitro, in situ, and in vivo. DRUG DELIVERY, [PMID:31913724] [10.1080/10717544.2019.1710623]
16. Qingquan Zeng, Mengru Bai, Cui Li, Shuanghui Lu, Zhiyuan Ma, Yunchun Zhao, Hui Zhou, Huidi Jiang, Dongli Sun, Caihong Zheng. (2019) Multiple Drug Transporters Contribute to the Placental Transfer of Emtricitabine. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, [PMID:31160284] [10.1128/AAC.00199-19]
17. Xueying Liu, Xiaoku Ran, Muhammad Riaz, Haixue Kuang, Deqiang Dou, Decheng Cai. (2019) Mechanism Investigation of Tagetes patula L. against Chronic Nonbacterial Prostatitis by Metabolomics and Network Pharmacology. MOLECULES, 24 (12): (2266). [PMID:31216740] [10.3390/molecules24122266]
18. Dong-Liang Lu, Samwel Mchele Limbu, Hong-Bo Lv, Qiang Ma, Li-Qiao Chen, Mei-Ling Zhang, Zhen-Yu Du. (2019) The comparisons in protective mechanisms and efficiencies among dietary α-lipoic acid, β-glucan and l-carnitine on Nile tilapia infected by Aeromonas hydrophila. FISH & SHELLFISH IMMUNOLOGY, 86 (785). [PMID:30553889] [10.1016/j.fsi.2018.12.023]
19. Liping Li, Yayun Weng, Wei Wang, Mengru Bai, Hongmei Lei, Hui Zhou, Huidi Jiang. (2017) Multiple organic cation transporters contribute to the renal transport of sulpiride. BIOPHARMACEUTICS & DRUG DISPOSITION, 38 (9): (526-534). [PMID:28926871] [10.1002/bdd.2104]
20. Tao Wu, Anqi Guo, Qingyu Shu, Yangjian Qi, Ying Kong, Zhiping Sun, Shumin Sun, Zhengwei Fu. (2015) l-Carnitine intake prevents irregular feeding-induced obesity and lipid metabolism disorder. GENE, 554 (148). [PMID:25445284] [10.1016/j.gene.2014.10.040]
21. Suo Decheng, Li Lan, Zhang Su, Su Xiaoou. (2012) Simultaneous determination of choline, carnitine and betaine in premixes by non-suppressed ion chromatography. Analytical Methods, 5 (1): (59-63). [PMID:] [10.1039/C2AY25955A]

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L(-)-Carnitine - 98%, high purity , CAS No.541-15-1