Grouped product items

SKU

Size

Availability

Price

Qty

L431483-100g

100g

Available within 8-12 weeks(?)

$314.90

L431483-500g

500g

Available within 8-12 weeks(?)

$1,083.90

Basic Description

Synonyms	(S)-2-Amino-5-guanidinopentanoic acid hydrochloride \| L-ARGININE HCL \| L-Arginine monohydrochloride, BioUltra, >=99.5% (AT) \| NSC-203450 \| ARGININE HYDROCHLORIDE [ORANGE BOOK] \| ARGININE HYDROCHLORIDE [USAN] \| L-ARGININE HYDROCHLORIDE [JAN] \| H-Arg-OH.HCl
Specifications & Purity	UltraBio™, Ultra pure, ≥99.5%(AT)
Biochemical and Physiological Mechanisms	L-Arginine is considered as a semi essential amino acid. In most mammals including humans, L-Arginine synthesis occurs through intestinal-renal axis, from glutamine, glutamate and proline. Abnormal levels of L-Arginine is associated with the development o
Grade	Ultra pure, UltraBio™
Product Description	Application L-Arginine monohydrochloride has been used to study the reversal of the inhibitory effect of L-N G 0-nitroarginine on non-cholinergic relaxations. It has also been used as a dietary supplement to study its effect on endothelium-dependent vasodilation.

AI Insight

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	(2S)-2-amino-5-(diaminomethylideneamino)pentanoic acid;hydrochloride
INCHI	InChI=1S/C6H14N4O2.ClH/c7-4(5(11)12)2-1-3-10-6(8)9;/h4H,1-3,7H2,(H,11,12)(H4,8,9,10);1H/t4-;/m0./s1
InChi Key	KWTQSFXGGICVPE-WCCKRBBISA-N
Canonical SMILES	Cl[H].N[C@@H](CCCNC(N)=N)C(O)=O
Isomeric SMILES	C(C[C@@H](C(=O)O)N)CN=C(N)N.Cl
WGK Germany	1
Alternate CAS	15595-35-4
PubChem CID	66250
Molecular Weight	210.66
Beilstein	6099937

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation
Precautionary Statements	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P264:Wash hands [and …] thoroughly after handling. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help.
WGK Germany	1
Merck Index	780

Reviews

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Qiang Zheng, Shuai He, Song-Lin Xu, Meng-Die Ma, Min Fan, Jin-Fang Ge. (2024) Pharmacokinetics and tissue distribution of vigabatrin enantiomers in rats. SAUDI PHARMACEUTICAL JOURNAL, 32 (101934). [PMID:38223203] [10.1016/j.jsps.2023.101934]
2. Yanbo Wang, Yongzheng Wang, Jian Chen, Shigenobu Koseki, Qing Yang, Hejun Yu, Linglin Fu. (2021) Screening and preservation application of quorum sensing inhibitors of Pseudomonas fluorescens and Shewanella baltica in seafood products. LWT-FOOD SCIENCE AND TECHNOLOGY, 149 (111749). [PMID:] [10.1016/j.lwt.2021.111749]
3. Yalin Ye, Xingli Huo, Zongning Yin. (2021) Protein-protein interactions at high concentrations: Effects of ArgHCl and NaCl on the stability, viscosity and aggregation mechanisms of protein solution. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 601 (120535). [PMID:33811966] [10.1016/j.ijpharm.2021.120535]
4. Jie Zhu, Hua Han, Faxue Li, Xueli Wang, Jianyong Yu, Chih-Chang Chu, Dequn Wu. (2019) Self-assembly of amino acid-based random copolymers for antibacterial application and infection treatment as nanocarriers. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 540 (634). [PMID:30690388] [10.1016/j.jcis.2018.12.091]

References

1. Rahul D Sheth,Mi Jin,Bharat V Bhut,Zhengjian Li,Wilfred Chen,Steven M Cramer. (2014-03-07) Affinity precipitation of a monoclonal antibody from an industrial harvest feedstock using an ELP-Z stimuli responsive biopolymer.. Biotechnology and bioengineering, 111 ((8)): (1595-1603). [PMID:24595842]
2. Lucie Holubova,Lucie Korecka,Stepan Podzimek,Veronika Moravcova,Jana Rotkova,Tereza Ehlova,Vladimir Velebny,Zuzana Bilkova. (2014-08-19) Enhanced multiparametric hyaluronan degradation for production of molar-mass-defined fragments.. Carbohydrate polymers, 112 (271-276). [PMID:25129744]
3. Nivaldo Ribeiro Villela,Ana Olimpia Maia Teixeira dos Santos,Marcos Lopes de Miranda,Eliete Bouskela. (2014-08-26) Fluid resuscitation therapy in endotoxemic hamsters improves survival and attenuates capillary perfusion deficits and inflammatory responses by a mechanism related to nitric oxide.. Journal of translational medicine, 12 (232-232). [PMID:25151363]
4. Carolina Di Somma,Alessandro Ciresi,Marco C Amato,Silvia Savastano,Maria Cristina Savanelli,Elisabetta Scarano,Annamaria Colao,Carla Giordano. (2014-11-10) Alteration of the growth hormone axis, visceral fat dysfunction, and early cardiometabolic risk in adults: the role of the visceral adiposity index.. Endocrine, 49 ((2)): (492-502). [PMID:25381601]
5. X Zheng,X Cheng,L Wang,W Qiu,S Wang,Y Zhou,M Li,Y Li,L Cheng,J Li,X Zhou,X Xu. (2014-12-06) Combinatorial effects of arginine and fluoride on oral bacteria.. Journal of dental research, 94 ((2)): (344-353). [PMID:25477312]
6. Hao Zheng, Cui Tang, Chunhua Yin,. (2014-12-24) Exploring advantages/disadvantages and improvements in overcoming gene delivery barriers of amino acid modified trimethylated chitosan.. Pharmaceutical research, 32 ((6)): ( 2038-2050 ). [PMID:25534683]
7. C B Christiansen,B Svendsen,J J Holst. (2015-01-21) The VGF-Derived Neuropeptide TLQP-21 Shows No Impact on Hormone Secretion in the Isolated Perfused Rat Pancreas.. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 47 ((7)): (537-543). [PMID:25602348]
8. Renata V Tiradentes,Cintia H Santuzzi,Erick Rg Claudio,Vinicius Mengal,Nyam F Silva,Henrique A F Neto,Nazaré S Bissoli,Glaucia R Abreu,Sonia A Gouvea. (2015-03-06) Combined Aliskiren and L-arginine treatment reverses renovascular hypertension in an animal model.. Hypertension research : official journal of the Japanese Society of Hypertension, 38 ((7)): (471-477). [PMID:25740291]
9. Yumiko Mizukoshi,Koh Takeuchi,Misa Arutaki,Takeshi Takizawa,Hiroyuki Hanzawa,Hideo Takahashi,Ichio Shimada. (2015-03-12) Suppression of problematic compound oligomerization by cosolubilization of nondetergent sulfobetaines.. ChemMedChem, 10 ((4)): (736-741). [PMID:25760302]
10. Jenna Gallie,Eric Libby,Frederic Bertels,Philippe Remigi,Christian B Jendresen,Gayle C Ferguson,Nicolas Desprat,Marieke F Buffing,Uwe Sauer,Hubertus J E Beaumont,Jan Martinussen,Mogens Kilstrup,Paul B Rainey. (2015-03-13) Bistability in a metabolic network underpins the de novo evolution of colony switching in Pseudomonas fluorescens.. PLoS biology, 13 ((3)): (e1002109-e1002109). [PMID:25763575]
11. L Rascón-Valenzuela,C Velázquez,A Garibay-Escobar,L A Medina-Juárez,W Vilegas,R E Robles-Zepeda. (2015-06-13) Antiproliferative activity of cardenolide glycosides from Asclepias subulata.. Journal of ethnopharmacology, 171 (280-286). [PMID:26068432]
12. Jun Yeul Lim,Nam Ah Kim,Dae Gon Lim,Ki Hyun Kim,Shavron Hada,Seong Hoon Jeong. (2015-07-19) Evaluation of etanercept degradation under oxidative stress and potential protective effects of various amino acids.. International journal of pharmaceutics, 492 ((1-2)): (127-136). [PMID:26187168]
13. Caroline Nava,Johanna Rupp,Jean-Paul Boissel,Cyril Mignot,Agnès Rastetter,Claire Amiet,Aurélia Jacquette,Céline Dupuits,Delphine Bouteiller,Boris Keren,Merle Ruberg,Anne Faudet,Diane Doummar,Anne Philippe,Didier Périsse,Claudine Laurent,Nicolas Lebrun,Vincent Guillemot,Jamel Chelly,David Cohen,Delphine Héron,Alexis Brice,Ellen I Closs,Christel Depienne. (2015-07-29) Hypomorphic variants of cationic amino acid transporter 3 in males with autism spectrum disorders.. Amino acids, 47 ((12)): (2647-2658). [PMID:26215737]
14. N E Paul,R Lösel,K Hemmrich,D Goy,N Pallua,D Klee. (2015-09-26) L-arginine and arginine ethyl ester enhance proliferation of endothelial cells and preadipocytes - how an arginine ethyl ester-releasing biomaterial could support endothelial cell growth in tissue engineering.. Bio-medical materials and engineering, 25 ((3)): (289-297). [PMID:26407115]
15. Enrique Niza,Matěj Božik,Iván Bravo,Pilar Clemente-Casares,Agustín Lara-Sanchez,Alberto Juan,Pavel Klouček,Carlos Alonso-Moreno. (2020-06-03) PEI-coated PLA nanoparticles to enhance the antimicrobial activity of carvacrol.. Food chemistry, 328 (127131-127131). [PMID:32485586]
16. Joseph J Dalluge,Jennifer L McCurtain,Adam J Gilbertsen,Kyle A Kalstabakken,Bryan J Williams. (2015-05-11) Determination of agmatine using isotope dilution UPLC-tandem mass spectrometry: application to the characterization of the arginine decarboxylase pathway in Pseudomonas aeruginosa.. Analytical and bioanalytical chemistry, 407 ((18)): (5513-5519). [PMID:25957842]
17. Qiang Zheng, Shuai He, Song-Lin Xu, Meng-Die Ma, Min Fan, Jin-Fang Ge. (2024) Pharmacokinetics and tissue distribution of vigabatrin enantiomers in rats. SAUDI PHARMACEUTICAL JOURNAL, 32 (101934). [PMID:38223203] [10.1016/j.jsps.2023.101934]
18. Yanbo Wang, Yongzheng Wang, Jian Chen, Shigenobu Koseki, Qing Yang, Hejun Yu, Linglin Fu. (2021) Screening and preservation application of quorum sensing inhibitors of Pseudomonas fluorescens and Shewanella baltica in seafood products. LWT-FOOD SCIENCE AND TECHNOLOGY, 149 (111749). [PMID:] [10.1016/j.lwt.2021.111749]
19. Yalin Ye, Xingli Huo, Zongning Yin. (2021) Protein-protein interactions at high concentrations: Effects of ArgHCl and NaCl on the stability, viscosity and aggregation mechanisms of protein solution. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 601 (120535). [PMID:33811966] [10.1016/j.ijpharm.2021.120535]
20. Jie Zhu, Hua Han, Faxue Li, Xueli Wang, Jianyong Yu, Chih-Chang Chu, Dequn Wu. (2019) Self-assembly of amino acid-based random copolymers for antibacterial application and infection treatment as nanocarriers. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 540 (634). [PMID:30690388] [10.1016/j.jcis.2018.12.091]

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L-Arginine monohydrochloride - Ultrapure BioReagent, ≥99.5% (AT), high purity , CAS No.1119-34-2