Basic Description

Synonyms	iodonium chloride \| Chlorine iodide (ClI) \| FT-0627251 \| Iodomono chloride \| Chloroiodide \| IODINE MONOCHLORIDE
Specifications & Purity	ACS
Storage Temp	Store at 2-8°C,Protected from light,Argon charged
Shipped In	Wet ice
Grade	ACS
Product Description	Iodine monochloride is an interhalogen compound. It forms various complexes with ethyl, isopropyl and t-butylbenzenes. Equilibrium constants for the formation of these complexes have been evaluated. It affords electrically conducting solution on dissolution in polar solvents. Its reaction with thymidine, 3-mono- and 3,3′,5′-trialkylsubstitued thymidine showed that it helps in deglycosylation, anomerization and isomerization of thymidine. Application： Iodine monochloride is used as a catalyst in organic synthesis. It is the source of electrophilic iodine in the synthesis of certain aromatic iodides. It is used to determine the iodine value of a substance. Iodine monochloride (ICl) may be employed for the halogenation of methoxy and dimethoxybenzenes. It may be used for the synthesis of flavones. Iodine monochloride may be used in the synthesis of the following: 2-(4-haloisoquinolin-1-yl)ethanol derivatives；5-iodosalicylaldehydes；5-aryl-6-iodo-8-phenylpyrazolo[1,5-c]-1,2,4-triazolo[4,3-a]pyrimidines；(±)-1-cyclohexyl-4-iodo-3-methoxybutan-1-ol；(±)-4-Iodo-3-methoxy-1-phenylbutan-1-ol.

AI Insight

Names and Identifiers

INCHI	InChI=1S/ClI/c1-2
InChi Key	QZRGKCOWNLSUDK-UHFFFAOYSA-N
Canonical SMILES	ClI
Isomeric SMILES	ClI
WGK Germany	3
RTECS	NN1650000
PubChem CID	24640
UN Number	17923498(liquid)
Packing Group	II
Molecular Weight	162.36
Beilstein	3587194

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

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8 results found

Lot Number	Certificate Type	Date	Item
C2307807	Certificate of Analysis	Dec 05, 2024	I102762
K2407548	Certificate of Analysis	Jul 13, 2024	I102762
G2412436	Certificate of Analysis	May 31, 2024	I102762
G2412442	Certificate of Analysis	May 31, 2024	I102762
E2013128	Certificate of Analysis	Dec 18, 2023	I102762
J1928086	Certificate of Analysis	Jun 07, 2023	I102762
G2326323	Certificate of Analysis	Feb 18, 2023	I102762
C2307823	Certificate of Analysis	Feb 16, 2023	I102762

Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS05
Signal	Danger
Hazard Statements	H335:May cause respiratory irritation H311:Toxic in contact with skin H314:Causes severe skin burns and eye damage H300:Fatal if swallowed
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P303+P361+P353:IF ON SKIN (or hair): Take off Immediately all contaminated clothing. Rinse SKIN with water [or shower]. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P361+P364:Take off immediately all contaminated clothing and wash it before reuse.
WGK Germany	3
RTECS	NN1650000
Class	8

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Citations of This Product

How to Cite Aladdin Scientific Products?

1. Cuicui Wu, Pan Feng, Xuan Guo, Yunming Fang. (2023) Purification of artemisinin precursor amorphadiene from microbial metabolites containing isomeride farnesene: Solid-Pd chemocatalysis of farnesene to squalene with high boiling point. CATALYSIS COMMUNICATIONS, 183 (15): (106770). [PMID:16393996] [10.1016/j.catcom.2023.106770]
2. Shuofan Li, Ying Liu, Yahe Zhang, Jianxun Wu, Weilai Zhang, Quan Shi. (2022) Molecular Characterization of Olefins in Petroleum Fractions by Iodine Monochloride Addition and Atmospheric Pressure Chemical Ionization Mass Spectrometry. ENERGY & FUELS, 36 (23): (14187–14193). [PMID:] [10.1021/acs.energyfuels.2c03128]
3. Youqun Chu, Xiaoping Zhang, Xinyu Liu, Hao Tang, Weitao Zhou, Kaiwen Li, Xin Liu, Zhaoyang Chen, Yinghong Zhu, Fengming Zhao. (2022) Effect of chloride ions on the indirect electrosynthesis of 2,6-dichlorobenzonitrile mediated by iodide. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 921 (116648). [PMID:] [10.1016/j.jelechem.2022.116648]
4. Weihua Liu, Juntao Wang, Shuangju Song, Lin Hao, Jiajia Liu, Yangjuan An, Yaxing Guo, Qiuhua Wu, Chun Wang, Zhi Wang. (2022) Facile synthesis of uniform spherical covalent organic frameworks for determination of neonicotinoid insecticides. FOOD CHEMISTRY, 367 (130653). [PMID:34343809] [10.1016/j.foodchem.2021.130653]
5. Bo Liang, Kai Shi, Yanfang Niu, Zhengchun Liu, Jianlong Zheng. (2020) Probing the modification mechanism of and customized processing design for SBS-modified asphalts mediated by potentiometric titration. CONSTRUCTION AND BUILDING MATERIALS, 234 (117385). [PMID:] [10.1016/j.conbuildmat.2019.117385]
6. Lian Li, Linyan Zhao, Yixi Wang, Jianning Wu, Guihua Meng, Zhiyong Liu, Jianshu Zhang, Baixing Hu, Qihui He, Xuhong Guo. (2018) Novel Dispersant with a Three-Dimensional Reticulated Structure for a Coal–Water Slurry. ENERGY & FUELS, 32 (8): (8310–8317). [PMID:] [10.1021/acs.energyfuels.8b01768]
7. Ping Shao, Qing Liu, Zhongxiang Fang, Peilong Sun. (2014) Chemical composition, thermal stability and antioxidant properties of tea seed oils obtained by different extraction methods: Supercritical fluid extraction yields the best oil quality. EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY, 117 (3): (355-365). [PMID:] [10.1002/ejlt.201400259]
8. Hengquan Yang, Guang Li, Zhancheng Ma, Jianbin Chao, Zhiqiang Guo. (2010) Three-dimensional cubic mesoporous materials with a built-in N-heterocyclic carbene for Suzuki–Miyaura coupling of aryl chlorides and C(sp3)-chlorides. JOURNAL OF CATALYSIS, 276 (123). [PMID:] [10.1016/j.jcat.2010.09.004]

References

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9. M Miyashita,R Matsunaga,Y Seyama,S Yamashita. (1999-10-08) [Studies on iodinated compounds. X. Isolation and purification of iodoglycyltyrosines].. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 119 ((9)): (681-687). [PMID:10511819]
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11. T Ercegovic,A Meijer,G Magnusson,U Ellervik. (2001-03-27) Iodine monochloride/silver trifluoromethanesulfonate (ICI/AgOTf) as a convenient promoter system for O-glycoside synthesis.. Organic letters, 3 ((6)): (913-915). [PMID:11263914]
12. J R Romero,R Martínez,O Fresnedo,B Ochoa. (2002-05-15) Comparison of two methods for radioiodination on the oxidizability properties of low density lipoprotein.. Journal of physiology and biochemistry, 57 ((4)): (291-301). [PMID:12005032]
13. Suman Lata,Kanchan Bhardwaj,Ram Rajasekharan. (2003-02-11) A single-step procedure for the synthesis of photoreactive and radioactive glycerolipids.. Analytical biochemistry, 313 ((1)): (155-159). [PMID:12576071]
14. Malledevarapura D Gowtham,Mysore S Yogendra Kumar,Mahadeshwarabetta A Sathish,Giddappa Nagendrappa. (2004-11-16) A novel spectrophotometric determination of some phenothiazines involving iodine monochloride from chloramine-T with iodine.. Archiv der Pharmazie, 337 ((11)): (605-614). [PMID:15543534]
15. M S Yogendra Kumar,M D Gowtham,Mahadevaiah,G Agendrappa. (2006-06-14) Simple spectrophotometric and titrimetric methods for the determination of sulfur dioxide.. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 22 ((5)): (757-761). [PMID:16770058]
16. Ru-Jin Huang,Thorsten Hoffmann. (2008-10-14) A denuder-impinger system with in situ derivatization followed by gas chromatography-mass spectrometry for the determination of gaseous iodine-containing halogen species.. Journal of chromatography. A, 1210 ((2)): (135-141). [PMID:18849042]
17. Ru-Jin Huang,Thorsten Hoffmann. (2009-02-10) Development of a coupled diffusion denuder system combined with gas chromatography/mass spectrometry for the separation and quantification of molecular iodine and the activated iodine compounds iodine monochloride and hypoiodous acid in the marine atmosphere.. Analytical chemistry, 81 ((5)): (1777-1783). [PMID:19199811]
18. Zan Qu,Naiqiang Yan,Ping Liu,Jinping Jia,Shijian Yang. (2010-08-03) The role of iodine monochloride for the oxidation of elemental mercury.. Journal of hazardous materials, 183 ((1-3)): (132-137). [PMID:20674159]
19. Thomas M Klapötke,Burkhard Krumm,Richard Moll,Sebastian F Rest,Yury V Vishnevskiy,Christian Reuter,Hans-Georg Stammler,Norbert W Mitzel. (2014-08-27) Halogenotrinitromethanes: a combined study in the crystalline and gaseous phase and using quantum chemical methods.. Chemistry (Weinheim an der Bergstrasse, Germany), 20 ((40)): (12962-12973). [PMID:25156478]
20. Ahmed Khalil,Keisuke Ishita,Tehane Ali,Rohit Tiwari,Ramy Riachy,Antonio Toppino,Sherifa Hasabelnaby,Naum Sayfullin,Allen G Oliver,Judith Gallucci,Zhenguo Huang,Werner Tjarks. (2014-11-06) Iodine monochloride facilitated deglycosylation, anomerization, and isomerization of 3-substituted thymidine analogues.. Nucleosides, nucleotides & nucleic acids, 33 ((12)): (786-799). [PMID:25372994]
21. L C Knight,A Z Budzynski,S A Olexa. (1981-10-01) Radiolabeling of fibrinogen using the iodogen technique.. Thrombosis and haemostasis, 46 ((3)): (593-596). [PMID:7314054]
22. Eric Stefan,Ansel P Nalin,Richard E Taylor. (2013-09-24) Concise enantioselective synthesis of diospongins A and B.. Tetrahedron, 69 ((36)): (7706-7712). [PMID:24058215]
23. Cuicui Wu, Pan Feng, Xuan Guo, Yunming Fang. (2023) Purification of artemisinin precursor amorphadiene from microbial metabolites containing isomeride farnesene: Solid-Pd chemocatalysis of farnesene to squalene with high boiling point. CATALYSIS COMMUNICATIONS, 183 (15): (106770). [PMID:16393996] [10.1016/j.catcom.2023.106770]
24. Shuofan Li, Ying Liu, Yahe Zhang, Jianxun Wu, Weilai Zhang, Quan Shi. (2022) Molecular Characterization of Olefins in Petroleum Fractions by Iodine Monochloride Addition and Atmospheric Pressure Chemical Ionization Mass Spectrometry. ENERGY & FUELS, 36 (23): (14187–14193). [PMID:] [10.1021/acs.energyfuels.2c03128]
25. Youqun Chu, Xiaoping Zhang, Xinyu Liu, Hao Tang, Weitao Zhou, Kaiwen Li, Xin Liu, Zhaoyang Chen, Yinghong Zhu, Fengming Zhao. (2022) Effect of chloride ions on the indirect electrosynthesis of 2,6-dichlorobenzonitrile mediated by iodide. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 921 (116648). [PMID:] [10.1016/j.jelechem.2022.116648]
26. Weihua Liu, Juntao Wang, Shuangju Song, Lin Hao, Jiajia Liu, Yangjuan An, Yaxing Guo, Qiuhua Wu, Chun Wang, Zhi Wang. (2022) Facile synthesis of uniform spherical covalent organic frameworks for determination of neonicotinoid insecticides. FOOD CHEMISTRY, 367 (130653). [PMID:34343809] [10.1016/j.foodchem.2021.130653]
27. Bo Liang, Kai Shi, Yanfang Niu, Zhengchun Liu, Jianlong Zheng. (2020) Probing the modification mechanism of and customized processing design for SBS-modified asphalts mediated by potentiometric titration. CONSTRUCTION AND BUILDING MATERIALS, 234 (117385). [PMID:] [10.1016/j.conbuildmat.2019.117385]
28. Lian Li, Linyan Zhao, Yixi Wang, Jianning Wu, Guihua Meng, Zhiyong Liu, Jianshu Zhang, Baixing Hu, Qihui He, Xuhong Guo. (2018) Novel Dispersant with a Three-Dimensional Reticulated Structure for a Coal–Water Slurry. ENERGY & FUELS, 32 (8): (8310–8317). [PMID:] [10.1021/acs.energyfuels.8b01768]
29. Ping Shao, Qing Liu, Zhongxiang Fang, Peilong Sun. (2014) Chemical composition, thermal stability and antioxidant properties of tea seed oils obtained by different extraction methods: Supercritical fluid extraction yields the best oil quality. EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY, 117 (3): (355-365). [PMID:] [10.1002/ejlt.201400259]
30. Hengquan Yang, Guang Li, Zhancheng Ma, Jianbin Chao, Zhiqiang Guo. (2010) Three-dimensional cubic mesoporous materials with a built-in N-heterocyclic carbene for Suzuki–Miyaura coupling of aryl chlorides and C(sp3)-chlorides. JOURNAL OF CATALYSIS, 276 (123). [PMID:] [10.1016/j.jcat.2010.09.004]

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SKU	Size	Availability	Price	Qty
I102762-25g	25g	2	$69.90
I102762-100g	100g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$195.90

Iodine monochloride - ACS, high purity , CAS No.7790-99-0