Indinavir sulfate - 10mM in DMSO, high purity , CAS No.157810-81-6, Human immunodeficiency virus type 1 protease inhibitor

Item Number

I421891

Grouped product items
SKU	Size	Availability	Price	Qty
I421891-1ml	1ml	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$69.90

Hydroxyaminopentane amide antiretroviral protease inhibitor

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Basic Description

Synonyms	Indinavir sulfate \| 157810-81-6 \| Crixivan \| INDINAVIR SULPHATE \| Indinavir (sulfate) \| MK-639 \| HSDB 7158 \| Indinaviri sulfas \| DRG-0233 \| MK 639 \| NSC-697197 \| CHEBI:5899 \| DTXSID1044221 \| L 735524 \| L-735,524 \| UNII-771H53976Q \| Indinavir sulfate [USAN:USP] \| 771H53976Q \| DTXCID9024221 \| L
Specifications & Purity	10mM in DMSO
Biochemical and Physiological Mechanisms	Hydroxyaminopentane amide antiretroviral protease inhibitor. Inhibits HIV-1 protease and suppresses HIV replication in vivo. Induces glutathione export from astrocytes. Orally active.
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads
Action Type	INHIBITOR
Mechanism of action	Human immunodeficiency virus type 1 protease inhibitor

Names and Identifiers

IUPAC Name	(2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-5-[[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino]-5-oxopentyl]-N-tert-butyl-4-(pyridin-3-ylmethyl)piperazine-2-carboxamide;sulfuric acid
INCHI	InChI=1S/C36H47N5O4.H2O4S/c1-36(2,3)39-35(45)31-24-40(22-26-12-9-15-37-21-26)16-17-41(31)23-29(42)19-28(18-25-10-5-4-6-11-25)34(44)38-33-30-14-8-7-13-27(30)20-32(33)43;1-5(2,3)4/h4-15,21,28-29,31-33,42-43H,16-20,22-24H2,1-3H3,(H,38,44)(H,39,45);(H2,1,2,3,4)/t28-,29+,31+,32-,33+;/m1./s1
InChi Key	NUBQKPWHXMGDLP-BDEHJDMKSA-N
Canonical SMILES	CC(C)(C)NC(=O)C1CN(CCN1CC(CC(CC2=CC=CC=C2)C(=O)NC3C(CC4=CC=CC=C34)O)O)CC5=CN=CC=C5.OS(=O)(=O)O
Isomeric SMILES	CC(C)(C)NC(=O)[C@@H]1CN(CCN1C[C@H](C[C@@H](CC2=CC=CC=C2)C(=O)N[C@@H]3[C@@H](CC4=CC=CC=C34)O)O)CC5=CN=CC=C5.OS(=O)(=O)O
PubChem CID	5462355
Molecular Weight	711.87

Safety and Hazards(GHS)

Pictogram(s)	GHS08, GHS07
Signal	Warning
Hazard Statements	H319:Causes serious eye irritation H361:Suspected of damaging fertility or the unborn child
Precautionary Statements	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P318:if exposed or concerned, get medical advice. P337+P317:If eye irritation persists: Get medical help.

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Basic Description