IL-4-inhibitor-1 - 98%, high purity , CAS No.1332184-63-0

Item Number

I647261

Grouped product items
SKU	Size	Availability	Price
I647261-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$50.90
I647261-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$240.90
I647261-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$420.90
I647261-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$790.90
I647261-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,280.90

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Basic Description

Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	IL-4-inhibitor-1 (compound 52) is an IL-4 inhibitor, with an EC 50 of 1.81 µM.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	IL-4-inhibitor-1 (compound 52) is an IL-4 inhibitor, with an EC 50 of 1.81 µM In Vitro IL-4-inhibitor-1 (compound 52) displays low micromolar affinity and exhibits functional disruption of type II IL-4 binding in a cellular context. IL-4-inhibitor-1 (compound 52) exhibits dose-dependent reduction in pSTAT-6 levels with an EC 50 value of 3.1 µM, but did not affect the levels of STAT-6. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:EC50: 1.81 µM (IL-4)

Names and Identifiers

IUPAC Name	2-amino-4-(3,4-dihydroxyphenyl)-6-(4-fluorophenyl)pyridine-3-carbonitrile
INCHI	InChI=1S/C18H12FN3O2/c19-12-4-1-10(2-5-12)15-8-13(14(9-20)18(21)22-15)11-3-6-16(23)17(24)7-11/h1-8,23-24H,(H2,21,22)
InChi Key	DWZPPBGRCDPFSS-UHFFFAOYSA-N
Canonical SMILES	C1=CC(=CC=C1C2=NC(=C(C(=C2)C3=CC(=C(C=C3)O)O)C#N)N)F
PubChem CID	136164931
Molecular Weight	321.31

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Basic Description