IL-21, Agonist of Interleukin-21 receptor, CAS No.rp174294, Agonist of Interleukin-21 receptor

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    Item Number
    rp174294
    Grouped product items
    SKUSizeAvailabilityPrice Qty
    rp174294-500μg
    500μg
    Available within 8-12 weeks(?)
    Production requires sourcing of materials. We appreciate your patience and understanding.
    $1,334.90
    rp174294-1mg
    1mg
    Available within 8-12 weeks(?)
    Production requires sourcing of materials. We appreciate your patience and understanding.
    $2,334.90

    Basic Description

    Product NameIL-21, Agonist of Interleukin-21 receptor, CAS No.rp174294
    Synonymsinterleukin-21;ZA11
    GradeMoligand™
    Specifications & PurityMoligand™
    Action TypeAGONIST
    Mechanism of actionAgonist of Interleukin-21 receptor

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    CASrp174294

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    References

    1. Wurster AL, Rodgers VL, Satoskar AR, Whitters MJ, Young DA, Collins M, Grusby MJ.  (2002)  Interleukin 21 is a T helper (Th) cell 2 cytokine that specifically inhibits the differentiation of naive Th cells into interferon gamma-producing Th1 cells..  J Exp Med,  196  (7): (969-77).  [PMID:12370258] [10.1021/op500134e]
    2. Lamprecht B, Kreher S, Anagnostopoulos I, Jöhrens K, Monteleone G, Jundt F, Stein H, Janz M, Dörken B, Mathas S.  (2008)  Aberrant expression of the Th2 cytokine IL-21 in Hodgkin lymphoma cells regulates STAT3 signaling and attracts Treg cells via regulation of MIP-3alpha..  Blood,  112  (8): (3339-47).  [PMID:18684866] [10.1021/op500134e]
    3. Wei L, Laurence A, Elias KM, O'Shea JJ.  (2007)  IL-21 is produced by Th17 cells and drives IL-17 production in a STAT3-dependent manner..  J Biol Chem,  282  (48): (34605-10).  [PMID:17884812] [10.1021/op500134e]
    4. Joalland N, Chauvin C, Oliver L, Vallette FM, Pecqueur C, Jarry U, Scotet E.  (2018)  IL-21 Increases the Reactivity of Allogeneic Human Vγ9Vδ2 T Cells Against Primary Glioblastoma Tumors..  J Immunother,  41  (5): (224-231).  [PMID:29683891] [10.1021/op500134e]

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