IL-2, Agonist of Interleukin-2 receptor, CAS No.rp174292, Agonist of Interleukin-2 receptor

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    Item Number
    rp174292
    Grouped product items
    SKUSizeAvailabilityPrice Qty
    rp174292-500μg
    500μg
    Available within 8-12 weeks(?)
    Production requires sourcing of materials. We appreciate your patience and understanding.
    $1,334.90
    rp174292-1mg
    1mg
    Available within 8-12 weeks(?)
    Production requires sourcing of materials. We appreciate your patience and understanding.
    $2,334.90

    Basic Description

    Product NameIL-2, Agonist of Interleukin-2 receptor, CAS No.rp174292
    Synonymsaldesleukin;interleukin-2;Proleukin
    GradeMoligand™
    Specifications & PurityMoligand™
    Action TypeAGONIST
    Mechanism of actionAgonist of Interleukin-2 receptor

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    CASrp174292

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    References

    1. Waldmann TA.  (2006)  The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design..  Nat Rev Immunol,  (8): (595-601).  [PMID:16868550] [10.1021/op500134e]
    2. Fontenot JD, Rasmussen JP, Gavin MA, Rudensky AY.  (2005)  A function for interleukin 2 in Foxp3-expressing regulatory T cells..  Nat Immunol,  (11): (1142-51).  [PMID:16227984] [10.1021/op500134e]
    3. Klatzmann D, Abbas AK.  (2015)  The promise of low-dose interleukin-2 therapy for autoimmune and inflammatory diseases..  Nat Rev Immunol,  15  (5): (283-94).  [PMID:25882245] [10.1021/op500134e]
    4. Abbas AK, Trotta E, R Simeonov D, Marson A, Bluestone JA.  (2018)  Revisiting IL-2: Biology and therapeutic prospects..  Sci Immunol,  (25): (1755-70).  [PMID:29980618] [10.1021/op500134e]
    5. Trotta E, Bessette PH, Silveria SL, Ely LK, Jude KM, Le DT, Holst CR, Coyle A, Potempa M, Lanier LL et al..  (2018)  A human anti-IL-2 antibody that potentiates regulatory T cells by a structure-based mechanism..  Nat Med,  24  (7): (1005-1014).  [PMID:29942088] [10.1021/op500134e]

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