IL-15, Agonist of Interleukin-15 receptor;Agonist of Interleukin-15 receptor subunit α, CAS No.rp174281, Agonist of Interleukin-15 receptor;Agonist of Interleukin-15 receptor subunit α

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    Item Number
    rp174281
    Grouped product items
    SKUSizeAvailabilityPrice Qty
    rp174281-500μg
    500μg
    Available within 8-12 weeks(?)
    Production requires sourcing of materials. We appreciate your patience and understanding.
    $1,334.90
    rp174281-1mg
    1mg
    Available within 8-12 weeks(?)
    Production requires sourcing of materials. We appreciate your patience and understanding.
    $2,334.90

    Basic Description

    Product NameIL-15, Agonist of Interleukin-15 receptor;Agonist of Interleukin-15 receptor subunit α, CAS No.rp174281
    Synonymsinterleukin-15
    GradeMoligand™
    Specifications & PurityMoligand™
    Action TypeAGONIST
    Mechanism of actionAgonist of Interleukin-15 receptor;Agonist of Interleukin-15 receptor subunit α

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    CASrp174281

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    References

    1. Waldmann TA.  (2006)  The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design..  Nat Rev Immunol,  (8): (595-601).  [PMID:16868550] [10.1021/op500134e]
    2. Finch DK, Midha A, Buchanan CL, Cochrane D, Craggs RI, Cruwys S, Grahames C, Kolbeck R, Lowe DC, Maltby J et al..  (2011)  Identification of a potent anti-IL-15 antibody with opposing mechanisms of action in vitro and in vivo..  Br J Pharmacol,  162  (2): (480-90).  [PMID:20942844] [10.1021/op500134e]
    3. Vicari AP, Schoepfer AM, Meresse B, Goffin L, Léger O, Josserand S, Guégan N, Yousefi S, Straumann A, Cerf-Bensussan N et al..  (2017)  Discovery and characterization of a novel humanized anti-IL-15 antibody and its relevance for the treatment of refractory celiac disease and eosinophilic esophagitis..  MAbs,  (6): (927-944).  [PMID:28581883] [10.1021/op500134e]
    4. Carson WE, Giri JG, Lindemann MJ, Linett ML, Ahdieh M, Paxton R, Anderson D, Eisenmann J, Grabstein K, Caligiuri MA.  (1994)  Interleukin (IL) 15 is a novel cytokine that activates human natural killer cells via components of the IL-2 receptor..  J Exp Med,  180  (4): (1395-403).  [PMID:7523571] [10.1021/op500134e]

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