IL-10, Agonist of Interleukin-10 receptor;Agonist of Interleukin 10 receptor; α subunit, CAS No.rp174275, Agonist of Interleukin-10 receptor;Agonist of Interleukin 10 receptor; α subunit

Features and benefits
    Item Number
    rp174275
    Grouped product items
    SKUSizeAvailabilityPrice Qty
    rp174275-500μg
    500μg
    Available within 8-12 weeks(?)
    Production requires sourcing of materials. We appreciate your patience and understanding.
    $1,334.90
    rp174275-1mg
    1mg
    Available within 8-12 weeks(?)
    Production requires sourcing of materials. We appreciate your patience and understanding.
    $2,334.90

    Basic Description

    Product NameIL-10, Agonist of Interleukin-10 receptor;Agonist of Interleukin 10 receptor; α subunit, CAS No.rp174275
    Synonymsinterleukin-10
    GradeMoligand™
    Specifications & PurityMoligand™
    Action TypeAGONIST
    Mechanism of actionAgonist of Interleukin-10 receptor;Agonist of Interleukin 10 receptor; α subunit

    AI Insight

    Product Specifications

    CASrp174275

    Certificates(CoA,COO,BSE/TSE and Analysis Chart)

    C of A & Other Certificates(BSE/TSE, COO):
    Analytical Chart:

    Related Documents

    Reviews

    Customer Reviews

    References

    1. O'Garra A, Vieira P.  (2007)  T(H)1 cells control themselves by producing interleukin-10..  Nat Rev Immunol,  (6): (425-8).  [PMID:17525751] [10.1021/op500134e]
    2. Schwager K, Kaspar M, Bootz F, Marcolongo R, Paresce E, Neri D, Trachsel E.  (2009)  Preclinical characterization of DEKAVIL (F8-IL10), a novel clinical-stage immunocytokine which inhibits the progression of collagen-induced arthritis..  Arthritis Res Ther,  11  (5): (R142).  [PMID:19781067] [10.1021/op500134e]
    3. Ryan JJ, Kashyap M, Bailey D, Kennedy S, Speiran K, Brenzovich J, Barnstein B, Oskeritzian C, Gomez G.  (2007)  Mast cell homeostasis: a fundamental aspect of allergic disease..  Crit Rev Immunol,  27  (1): (15-32).  [PMID:17430094] [10.1021/op500134e]
    4. Fillatreau S, Gray D, Anderton SM.  (2008)  Not always the bad guys: B cells as regulators of autoimmune pathology..  Nat Rev Immunol,  (5): (391-7).  [PMID:18437156] [10.1021/op500134e]
    5. Naing A, Papadopoulos KP, Autio KA, Ott PA, Patel MR, Wong DJ, Falchook GS, Pant S, Whiteside M, Rasco DR et al..  (2016)  Safety, Antitumor Activity, and Immune Activation of Pegylated Recombinant Human Interleukin-10 (AM0010) in Patients With Advanced Solid Tumors..  J Clin Oncol,  34  (29): (3562-3569).  [PMID:27528724] [10.1021/op500134e]
    6. Naing A, Infante JR, Papadopoulos KP, Chan IH, Shen C, Ratti NP, Rojo B, Autio KA, Wong DJ, Patel MR et al..  (2018)  PEGylated IL-10 (Pegilodecakin) Induces Systemic Immune Activation, CD8+ T Cell Invigoration and Polyclonal T Cell Expansion in Cancer Patients..  Cancer Cell,  34  (5): (775-791.e3).  [PMID:30423297] [10.1021/op500134e]

    Solution Calculators