| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| H424307-1ml | 1ml | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $69.90 |
Glucocorticoid anti-inflammatory agent
| Synonyms | hydrocortisone acetate | 50-03-3 | Cortisol 21-acetate | Cortell | Hydrocortisone 21-acetate | Cortifoam | Cortef acetate | Cortisol acetate | Lanacort | Hydrocortisat | Hydrocortistab | Abbocort | Bambicort | Biocortar | Chemysone | Cortacream | Hydrosone | Pabracort | Resicort | Cortaid | Cor |
|---|---|
| Specifications & Purity | 10mM in DMSO |
| Biochemical and Physiological Mechanisms | Glucocorticoid. Hydrocortisone ( Asc 1250 ) derivative. Anti-inflammatory and centrally mediated behavioural effects in vivo. Orally active. |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Action Type | AGONIST |
| Mechanism of action | Glucocorticoid receptor agonist |
| ALogP | 2.2 |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| IUPAC Name | [2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate |
|---|---|
| INCHI | InChI=1S/C23H32O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h10,16-18,20,26,28H,4-9,11-12H2,1-3H3/t16-,17-,18-,20+,21-,22-,23-/m0/s1 |
| InChi Key | ALEXXDVDDISNDU-JZYPGELDSA-N |
| Canonical SMILES | CC(=O)OCC(=O)C1(CCC2C1(CC(C3C2CCC4=CC(=O)CCC34C)O)C)O |
| Isomeric SMILES | CC(=O)OCC(=O)[C@]1(CC[C@@H]2[C@@]1(C[C@@H]([C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)O)C)O |
| WGK Germany | 3 |
| RTECS | GM8960000 |
| PubChem CID | 5744 |
| Molecular Weight | 404.5 |
| Beilstein | 2066841 |
| Pictogram(s) | GHS08, GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H302:Harmful if swallowed H312:Harmful in contact with skin H332:Harmful if inhaled H361:Suspected of damaging fertility or the unborn child |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. P317:Get emergency medical help. |
| WGK Germany | 3 |
| RTECS | GM8960000 |
| Merck Index | 4787 |
| 1. Zhefei Hu, Yanhao Jiang, Panpan Cao, Yanjuan Liu, Yuefei Zhang, Wei Chen, Sheng Tang. (2023) Performance evaluation of 2-undecylimidazole/propyl methacrylate bifunctional silica gel for mixed-mode reversed-phase/anion-exchange chromatography. MICROCHEMICAL JOURNAL, 191 (108768). [PMID:] [10.1016/j.microc.2023.108768] |
| 2. Yuanjiao Liu, Yi Wang, Songyao Zhang, Hengqi Zou, Xinrui Miao, Wenli Deng. (2023) Fabricating 2D Host −Guest Kagomé Packing for C2-Symmetric Aromatic Carboxylic Acids with Different Spatial Configuration: Different Ways, Same Destination. Journal of Physical Chemistry C, 127 (15): (7402–7409). [PMID:] [10.1021/acs.jpcc.2c08436] |
| 3. Yajiao Zhang, Minjie Liu, Huijing Wang, Juan Lin, Fener Chen. (2022) Focused mutagenesis in non-catalytic cavity for improving catalytic efficiency of 3-ketosteroid-Δ1-dehydrogenase. Molecular Catalysis, 531 (112661). [PMID:] [10.1016/j.mcat.2022.112661] |
| 1. Zhefei Hu, Yanhao Jiang, Panpan Cao, Yanjuan Liu, Yuefei Zhang, Wei Chen, Sheng Tang. (2023) Performance evaluation of 2-undecylimidazole/propyl methacrylate bifunctional silica gel for mixed-mode reversed-phase/anion-exchange chromatography. MICROCHEMICAL JOURNAL, 191 (108768). [PMID:] [10.1016/j.microc.2023.108768] |
| 2. Yuanjiao Liu, Yi Wang, Songyao Zhang, Hengqi Zou, Xinrui Miao, Wenli Deng. (2023) Fabricating 2D Host −Guest Kagomé Packing for C2-Symmetric Aromatic Carboxylic Acids with Different Spatial Configuration: Different Ways, Same Destination. Journal of Physical Chemistry C, 127 (15): (7402–7409). [PMID:] [10.1021/acs.jpcc.2c08436] |
| 3. Yajiao Zhang, Minjie Liu, Huijing Wang, Juan Lin, Fener Chen. (2022) Focused mutagenesis in non-catalytic cavity for improving catalytic efficiency of 3-ketosteroid-Δ1-dehydrogenase. Molecular Catalysis, 531 (112661). [PMID:] [10.1016/j.mcat.2022.112661] |
