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GW853606 , CAS No.G610776, Inhibitor of polo like kinase 1

Item Number

G610776

Grouped product items
SKU	Size	Availability	Price	Qty
G610776-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$922.90
G610776-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$4,000.90

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Basic Description

Synonyms	compound 22;GW853606X
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of polo like kinase 1

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

IUPAC Name	3-[(2-bromophenyl)methoxy]-5-[6-(trifluoromethyl)benzimidazol-1-yl]thiophene-2-carboxamide
INCHI	InChI=1S/C20H13BrF3N3O2S/c21-13-4-2-1-3-11(13)9-29-16-8-17(30-18(16)19(25)28)27-10-26-14-6-5-12(7-15(14)27)20(22,23)24/h1-8,10H,9H2,(H2,25,28)
InChi Key	LOKKVFGDJAVMLU-UHFFFAOYSA-N
Canonical SMILES	NC(=O)c1sc(cc1OCc1ccccc1Br)n1cnc2c1cc(cc2)C(F)(F)F
Isomeric SMILES	C1=CC=C(C(=C1)COC2=C(SC(=C2)N3C=NC4=C3C=C(C=C4)C(F)(F)F)C(=O)N)Br
PubChem CID	25263088

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

1. Emmitte KA, Andrews CW, Badiang JG, Davis-Ward RG, Dickson HD, Drewry DH, Emerson HK, Epperly AH, Hassler DF, Knick VB et al.. (2009) Discovery of thiophene inhibitors of polo-like kinase.. Bioorg Med Chem Lett, 19 (3): (1018-21). [PMID:19097784] [10.1021/op500134e]

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