Guggulsterone(pregna-4,17-diene-3,16-dione) - ≥98%, high purity , CAS No.95975-55-6, Antagonist of Farnesoid X receptor

Item Number
G276180
Grouped product items
SKUSizeAvailabilityPrice Qty
G276180-2mg
2mg
2
$36.90
G276180-5mg
5mg
2
$75.90
G276180-10mg
10mg
3
$140.90
G276180-50mg
50mg
3
$434.90
G276180-100mg
100mg
3
$761.90

Broad spectrum steroid receptor antagonist

Basic Description

SynonymsAVQFHKYAVVQYQO-UHFFFAOYSA- | 6CST3U34GN | GUGGULSTERONE Z [USP-RS] | NCGC00260067-01 | Z/E-Guggulsterone | AC-28813 | CHEBI:135338 | Guggulsterones Z | 2-(2-Aminothiazol-3(2H)-yl)-1-phenylethanone | Guggulsterone | AC-6215 | Q27264514 | (17Z)-Guggulsteron
Specifications & PurityMoligand™, ≥98%
Biochemical and Physiological MechanismsBroad spectrum steroid receptor antagonist (K i values are 39, 224 and 240 nM for mineralocorticoid, glucocorticoid and androgen receptors respectively). Partial progesterone receptor agonist (K i = 201 nM). Shows hypoglycemic and hypolipidemic effects in
Storage TempProtected from light,Store at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeANTAGONIST
Mechanism of actionAntagonist of Farnesoid X receptor
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Store at Room Temperature. The product can be stored for up to 12 months.

AI Insight

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name (8R,9S,10R,13S,14S,17Z)-17-ethylidene-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15-decahydrocyclopenta[a]phenanthrene-3,16-dione
INCHI InChI=1S/C21H28O2/c1-4-16-19(23)12-18-15-6-5-13-11-14(22)7-9-20(13,2)17(15)8-10-21(16,18)3/h4,11,15,17-18H,5-10,12H2,1-3H3/b16-4+/t15-,17+,18+,20+,21-/m1/s1
InChi Key WDXRGPWQVHZTQJ-OSJVMJFVSA-N
Canonical SMILES CC=C1C(=O)CC2C1(CCC3C2CCC4=CC(=O)CCC34C)C
Isomeric SMILES C/C=C/1\C(=O)C[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C
PubChem CID 6450278
Molecular Weight 312.45

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot NumberCertificate TypeDateItem
K2218700Certificate of AnalysisSep 15, 2023 G276180
K2218771Certificate of AnalysisSep 15, 2023 G276180
K2218776Certificate of AnalysisSep 15, 2023 G276180
K2218866Certificate of AnalysisSep 15, 2023 G276180
K2218867Certificate of AnalysisSep 15, 2023 G276180

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

Precautionary Statements

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P264:Wash hands [and …] thoroughly after handling.

P362+P364:Take off contaminated clothing and wash it before reuse.

P332+P317:If skin irritation occurs: Get medical help.

Related Documents

Reviews

Customer Reviews

Solution Calculators