GSK872 - ≥98%, high purity , CAS No.1346546-69-7

Item Number

G276439

Grouped product items
SKU	Size	Availability	Price
G276439-5mg	5mg	3	$68.90
G276439-10mg	10mg	3	$115.90
G276439-25mg	25mg	2	$188.90
G276439-50mg	50mg	2	$353.90
G276439-100mg	100mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$528.90

Highly potent, selective RIP3 inhibitor

View related series

Basic Description

Synonyms	GSK′872 \| N-(6-(Isopropylsulfonyl)quinolin-4-yl)benzo[d]thiazol-5-amine
Specifications & Purity	Moligand™, ≥98%
Biochemical and Physiological Mechanisms	GSK-872 is a RIPK3 inhibitor that binds to the RIP3 kinase domain with high affinity, with an IC50 of 1.8 nM, and inhibits kinase activity, with an IC50 of 1.3 nM. GSK-872 reduces RIPK3 mediated necroptosis and subsequent cytoplasmic translocation and exp
Storage Temp	Protected from light,Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Note	Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	GSK'872 is a potent and selective RIP3 kinase inhibitor which binds RIP3 kinase domain with high affinity (IC50=1.8 nM) and inhibits kinase activity with IC50 of 1.3 nM. It has minimal cross-reactivity.

Names and Identifiers

Pubchem Sid	504771335
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504771335
IUPAC Name	N-(6-propan-2-ylsulfonylquinolin-4-yl)-1,3-benzothiazol-5-amine
INCHI	InChI=1S/C19H17N3O2S2/c1-12(2)26(23,24)14-4-5-16-15(10-14)17(7-8-20-16)22-13-3-6-19-18(9-13)21-11-25-19/h3-12H,1-2H3,(H,20,22)
InChi Key	ZCDBTQNFAPKACC-UHFFFAOYSA-N
Canonical SMILES	CC(C)S(=O)(=O)C1=CC2=C(C=CN=C2C=C1)NC3=CC4=C(C=C3)SC=N4
Isomeric SMILES	CC(C)S(=O)(=O)C1=CC2=C(C=CN=C2C=C1)NC3=CC4=C(C=C3)SC=N4
PubChem CID	54674134
Molecular Weight	383.48

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

8 results found

Lot Number	Certificate Type	Date	Item
L2419651	Certificate of Analysis	Dec 11, 2024	G276439
L2419652	Certificate of Analysis	Dec 11, 2024	G276439
L2419653	Certificate of Analysis	Dec 11, 2024	G276439
A2214477	Certificate of Analysis	Oct 21, 2022	G276439
A2214478	Certificate of Analysis	Oct 21, 2022	G276439
A2214428	Certificate of Analysis	Oct 21, 2022	G276439
A2214429	Certificate of Analysis	Oct 21, 2022	G276439
A2214430	Certificate of Analysis	Dec 20, 2021	G276439

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

Solution Calculators

Determine the necessary mass, volume, or concentration for preparing a solution.

Determine the dilution needed to prepare a stock solution.

Basic Description