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GRI 977143 - ≥98%(HPLC), high purity , CAS No.325850-81-5, Agonist of LPA 2 receptor
Selective LPA2receptor non-lipid agonist
Basic Description Synonyms 2-((3-(1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)propyl)thio)benzoicacid | 2-[[3-(1,3-dioxo-1H-benz[de]isoquinolin-2(3H)-yl)propyl]thio]benzoic acid | SCHEMBL15490694 | 2-[3-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-propylsulfanyl]-benzoic acid | M3L07 Specifications & Purity Moligand™, ≥98%(HPLC) Biochemical and Physiological Mechanisms Selective lysophosphatidic acid 2 (LPA2) receptor non-lipid agonist (EC50= 3.3μM). Does not activate other LPA GPCRs at concentrations up to 10μM. Antiapoptotic; inhibits activation of caspases 3, 7, 8 and 9, Bax translocation and PARP-1 cleavage. Activat Storage Temp Store at 2-8°C Shipped In Wet ice Grade Moligand™ Action Type AGONIST Mechanism of action Agonist of LPA 2 receptor
Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers Pubchem Sid 504762465 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504762465 IUPAC Name 2-[3-(1,3-dioxobenzo[de]isoquinolin-2-yl)propylsulfanyl]benzoic acid INCHI InChI=1S/C22H17NO4S/c24-20-16-9-3-6-14-7-4-10-17(19(14)16)21(25)23(20)12-5-13-28-18-11-2-1-8-15(18)22(26)27/h1-4,6-11H,5,12-13H2,(H,26,27) InChi Key GMVZUCHUOYUMLL-UHFFFAOYSA-N Canonical SMILES C1=CC=C(C(=C1)C(=O)O)SCCCN2C(=O)C3=CC=CC4=C3C(=CC=C4)C2=O Isomeric SMILES C1=CC=C(C(=C1)C(=O)O)SCCCN2C(=O)C3=CC=CC4=C3C(=CC=C4)C2=O PubChem CID 3114900 Molecular Weight 391.44
Certificates（CoA,COO,BSE/TSE and Analysis Chart) Safety and Hazards(GHS) Pictogram(s) GHS09 , GHS07 Signal Warning Hazard Statements H302: Harmful if swallowed
H400: Very toxic to aquatic life
H410: Very toxic to aquatic life with long lasting effects
Precautionary Statements P273: Avoid release to the environment.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P391: Collect spillage.
P330: Rinse mouth.
P301+P317: IF SWALLOWED: Get medical help.
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H2301181