| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| G649004-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,350.90 |
| Specifications & Purity | ≥92% |
|---|---|
| Storage Temp | Store at -20°C,Argon charged,Desiccated |
| Shipped In | Ice chest + Ice pads |
| Product Description | Golodirsen (SRP-4053) is a phosphorodiamidate morpholino oligomer (PMO) that specifically targets exon 53 of dystrophin pre-mRNA. Golodirsen can be used for the research of Duchenne muscular dystrophy (DMD). In Vitro Golodirsen specifically targets exon 53 of dystrophin pre-mRNA, resulting in its exclusion from the final mRNA product. Skipping of exon 53 results in restoration of the mRNA reading frame and leads to the production of a partially internally deleted dystrophin protein with intact C and N-terminal regions. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid |
| Canonical SMILES | [Golodirsen] |
|---|---|
| Molecular Weight | 8647.00 |
| Solubility | H2O : 100 mg/mL (11.56 mM; Need ultrasonic) |
|---|
