GAP-134 , CAS No.943134-39-2

CAS: 943134-39-2 Cat. No.: G126343 Molecular Weight: 291.3
AVAILABLE TO ORDER
Synonyms
DB11821 | DTXSID201026039 | Q27286426 | [2s,4r]-1-(2-aminoacetyl)-4-benzamidopyrrolidine-2-carboxylic acid | US9345789, Z-DEVD-FMK | A917262 | (2S,4R)-4-benzamido-1-glycylpyrrolidine-2-carboxylic acid | Danegaptide (USAN/INN) | UNII-PA0Y7735AT | (2S,4R)-1
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
5mg
G126343-5mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$199.90
10mg
G126343-10mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$397.90
50mg
G126343-50mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$735.90
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Why this grade

for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
DB11821 | DTXSID201026039 | Q27286426 | [2s, 4r]-1-(2-aminoacetyl)-4-benzamidopyrrolidine-2-carboxylic acid | US9345789, Z-DEVD-FMK | A917262 | (2S, 4R)-4-benzamido-1-glycylpyrrolidine-2-carboxylic acid | Danegaptide (USAN/INN) | UNII-PA0Y7735AT | (2S, 4R)-1
Biochemical and Physiological Mechanisms

Gap junction uncoupling can alter conduction pathways and promote cardiac re-entry mechanisms that potentiate many supraventricular arrhythmias, such as atrial fibrillation (AF) and atrial flutter (AFL). GAP-134 (Danegaptide), a small mod

Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
MODULATOR
Names and Identifiers
Canonical SmilesC1C(CN(C1C(=O)O)C(=O)CN)NC(=O)C2=CC=CC=C2
IUPAC Name(2S,4R)-1-(2-aminoacetyl)-4-benzamidopyrrolidine-2-carboxylic acid
InChIKeyBIZKIHUJGMSVFD-MNOVXSKESA-N
INCHI1S/C14H17N3O4/c15-7-12(18)17-8-10(6-11(17)14(20)21)16-13(19)9-4-2-1-3-5-9/h1-5,10-11H,6-8,15H2,(H,16,19)(H,20,21)/t10-,11+/m1/s1
Isomeric SMILES C1[C@H](CN([C@@H]1C(=O)O)C(=O)CN)NC(=O)C2=CC=CC=C2
Molecular Weight 291.3
Reaxy-Rn 12905325
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=12905325&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Associated Targets(non-human)
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Canis familiaris (36305 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
SolubilityDMSO
Molecular Weight291.300 g/mol
XLogP3-2.700
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Exact Mass291.122 Da
Monoisotopic Mass291.122 Da
Topological Polar Surface Area113.000 Ų
Heavy Atom Count21
Formal Charge0
Complexity420.000
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Solution Calculators
Reviews

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