Boc-Cys(trt)-OH - ≥99% , CAS No.21947-98-8

CAS: 21947-98-8 Cat. No.: B103066 Molecular Weight: 463.59 Beilstein Registry Number: 2028965 EC Number: 244-674-6

GRADE & PURITY ≥99%

Synonyms

(2R)-2-(tert-butoxycarbonylamino)-3-tritylsulfanyl-propanoic acid;Boc-Cys(Trt)-OH | N-alpha-t-Butyloxycarbonyl-S-trityl-L-cysteine | BS-21032 | (R)-2-((tert-Butoxycarbonyl)amino)-3-(tritylthio)propanoic acid | J-300086 | N-BOC-S-trityl-cysteine | Boc-S-tr

Storage

Store at 2-8°C

Shipped In

Wet ice

Specifications

Synonyms

(2R)-2-(tert-butoxycarbonylamino)-3-tritylsulfanyl-propanoic acid;Boc-Cys(Trt)-OH | N-alpha-t-Butyloxycarbonyl-S-trityl-L-cysteine | BS-21032 | (R)-2-((tert-Butoxycarbonyl)amino)-3-(tritylthio)propanoic acid | J-300086 | N-BOC-S-trityl-cysteine | Boc-S-tr

Specifications & Purity

≥99%

Storage

Store at 2-8°C

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥99%

Names and Identifiers

• Pubchem Sid: 504766101
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504766101
• Canonical Smiles: CC(C)(C)OC(=O)NC(CSC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)C(=O)O
• IUPAC Name: (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-tritylsulfanylpropanoic acid
• InChIKey: JDTOWOURWBDELG-QHCPKHFHSA-N
• INCHI: 1S/C27H29NO4S/c1-26(2,3)32-25(31)28-23(24(29)30)19-33-27(20-13-7-4-8-14-20,21-15-9-5-10-16-21)22-17-11-6-12-18-22/h4-18,23H,19H2,1-3H3,(H,28,31)(H,29,30)/t23-/m0/s1
• Isomeric SMILES: CC(C)(C)OC(=O)N[C@@H](CSC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)C(=O)O
• WGK Germany: 3
• Molecular Weight: 463.59
• Beilstein: 2028965
• Reaxy-Rn: 2572425
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2572425&ln=

Associated Targets(Human)

HeLa (62764 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Chemical and Physical Properties

• Sensitivity: Heat sensitive
• Specific Rotation[α]: [α]D 29° (C=1,EtOH)
• Melt Point(°C): 147 °C(dec.)
• Molecular Weight: 463.600 g/mol
• XLogP3: 5.900
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 10
• Exact Mass: 463.182 Da
• Monoisotopic Mass: 463.182 Da
• Topological Polar Surface Area: 101.000 Ų
• Heavy Atom Count: 33
• Formal Charge: 0
• Complexity: 583.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Xi Li, Qingzhu Liu, Siqin Ye, Shijie Wang, Ke Li, Gaochao Lv, Ying Peng, Ling Qiu, Jianguo Lin.  (2019)  A protease-responsive fluorescent probe for sensitive imaging of legumain activity in living tumor cells.  Chemical Biology & Drug Design,  94  (2): (1494-1503).  [PMID:31002467] [10.1111/cbdd.13530]

2. Xueyu Zhao, Gaochao Lv, Ying Peng, Qingzhu Liu, Xi Li, Shanshan Wang, Ke Li, Ling Qiu, Jianguo Lin.  (2018)  Targeted Delivery of an Activatable Fluorescent Probe for the Detection of Furin Activity in Living Cells.  CHEMBIOCHEM,  19  (10): (1060-1065).  [PMID:29465834] [10.1002/cbic.201800015]