Lasofoxifene Tartrate - 10mM in DMSO , CAS No.190791-29-8

CAS: 190791-29-8 Cat. No.: L422334 Molecular Weight: 563.65 EC Number: 638-818-0 PubChem CID: 3081919

GRADE & PURITY 10mM in DMSO

Synonyms

C73647 | SCHEMBL1649247 | 2-Naphthalenol, 5,6,7,8-tetrahydro-6-phenyl-5-(4-(2-(1-pyrrolidinyl)ethoxy)phenyl)-, (5R,6S)-, (2S,3S)-2,3-dihydroxybutanedioate (1:1) (salt) | 2-Naphthalenol, 5,6,7,8-tetrahydro-6-phenyl-5-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-,

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

product description：

Lasofoxifene Tartrate is a non-steroidal selective estrogen receptor modulator (SERM).

Specifications

Synonyms

C73647 | SCHEMBL1649247 | 2-Naphthalenol, 5, 6, 7, 8-tetrahydro-6-phenyl-5-(4-(2-(1-pyrrolidinyl)ethoxy)phenyl)-, (5R, 6S)-, (2S, 3S)-2, 3-dihydroxybutanedioate (1:1) (salt) | 2-Naphthalenol, 5, 6, 7, 8-tetrahydro-6-phenyl-5-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-,

Specifications & Purity

10mM in DMSO

Biochemical and Physiological Mechanisms

Lasofoxifene is a third-generation selective estrogen receptor modulator (SERM). Lasofoxifene possesses strong resistance to intestinal wall glucuronidation and thus promotes oral bioavailability. In postmenopausal women, it reduces bone resorption, bone

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Canonical Smiles: C1CCN(C1)CCOC2=CC=C(C=C2)C3C(CCC4=C3C=CC(=C4)O)C5=CC=CC=C5.C(C(C(=O)O)O)(C(=O)O)O
• IUPAC Name: (2S,3S)-2,3-dihydroxybutanedioic acid;(5R,6S)-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol
• InChIKey: INEHJXCWEVNEDZ-LUDNRVPPSA-N
• INCHI: 1S/C28H31NO2.C4H6O6/c30-24-11-15-27-23(20-24)10-14-26(21-6-2-1-3-7-21)28(27)22-8-12-25(13-9-22)31-19-18-29-16-4-5-17-29;5-1(3(7)8)2(6)4(9)10/h1-3,6-9,11-13,15,20,26,28,30H,4-5,10,14,16-19H2;1-2,5-6H,(H,7,8)(H,9,10)/t26-,28+;1-,2-/m10/s1
• Isomeric SMILES: C1CCN(C1)CCOC2=CC=C(C=C2)[C@H]3[C@H](CCC4=C3C=CC(=C4)O)C5=CC=CC=C5.[C@H]([C@@H](C(=O)O)O)(C(=O)O)O
• RTECS: QK4252964
• PubChem CID: 3081919
• Molecular Weight: 563.65
• Reaxy-Rn: 14771789

Chemical and Physical Properties

• Sensitivity: Air Sensitive,Hygroscopic,Heat Sensitive
• Melt Point(°C): 185 °C(dec.)
• Molecular Weight: 563.600 g/mol
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 9
• Exact Mass: 563.252 Da
• Monoisotopic Mass: 563.252 Da
• Topological Polar Surface Area: 148.000 Ų
• Heavy Atom Count: 41
• Formal Charge: 0
• Complexity: 667.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 4
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

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