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· · COA & SDS available for every product · Same-day shipping on in-stock items EMD638683 - Moligand™, 10mM in DMSO , Inhibitor of serum/glucocorticoid regulated kinase 1, CAS No.1181770-72-8, Inhibitor of serum/glucocorticoid regulated kinase 1
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO Synonyms
A925647 | Z3247511913 | BCP29409 | EMD 638683; EMD-638683 | C18H18F2N2O4 | HY-15193 | 1181770-72-8 | 2-(3,5-DIFLUOROPHENYL)-N'-(2-ETHYL-4-HYDROXY-3-METHYLBENZOYL)-2-HYDROXYACETOHYDRAZIDE | EN300-19790884 | D71037 | GTPL9407 | N'-[2-(3,5-difluorophenyl)-2-
Shipped In
Dry ice packs + Cold packs
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Why this grade Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
A925647 | Z3247511913 | BCP29409 | EMD 638683; EMD-638683 | C18H18F2N2O4 | HY-15193 | 1181770-72-8 | 2-(3, 5-DIFLUOROPHENYL)-N'-(2-ETHYL-4-HYDROXY-3-METHYLBENZOYL)-2-HYDROXYACETOHYDRAZIDE | EN300-19790884 | D71037 | GTPL9407 | N'-[2-(3, 5-difluorophenyl)-2-
Specifications & Purity
Moligand™, 10mM in DMSO
Biochemical and Physiological Mechanisms
Description: IC50 Value: 3 μM EMD638683 is a SGK1 inhibitor.The serum- and glucocorticoid-inducible kinase 1 (SGK1) is transcriptionally upregulated by mineralocorticoids and activated by insulin. EMD638683 could serve as a template fo
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Mechanism of action
Inhibitor of serum/glucocorticoid regulated kinase 1
Names and Identifiers Canonical Smiles CCC1=C(C=CC(=C1C)O)C(=O)NNC(=O)C(C2=CC(=CC(=C2)F)F)O IUPAC Name N'-[2-(3,5-difluorophenyl)-2-hydroxyacetyl]-2-ethyl-4-hydroxy-3-methylbenzohydrazide InChIKey SSNAPUUWBPZGOY-UHFFFAOYSA-N INCHI 1S/C18H18F2N2O4/c1-3-13-9(2)15(23)5-4-14(13)17(25)21-22-18(26)16(24)10-6-11(19)8-12(20)7-10/h4-8,16,23-24H,3H2,1-2H3,(H,21,25)(H,22,26) Isomeric SMILES CCC1=C(C=CC(=C1C)O)C(=O)NNC(=O)C(C2=CC(=CC(=C2)F)F)O Molecular Weight 364.34 Reaxy-Rn 21240670 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=21240670&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Associated Targets(Human) Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Molecular Weight 364.300 g/mol XLogP3 2.800 Hydrogen Bond Donor Count 4 Hydrogen Bond Acceptor Count 6 Rotatable Bond Count 4 Exact Mass 364.123 Da Monoisotopic Mass 364.123 Da Topological Polar Surface Area 98.700 Ų Heavy Atom Count 26 Formal Charge 0 Complexity 498.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 1 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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