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SRT 1460 - ≥98% , CAS No.925432-73-1

CAS: 925432-73-1 Cat. No.: S334321 Molecular Weight: 507.62 PubChem CID: 24180124
COA
SRT 1460 - ≥98% CAS No(925432-73-1) by Aladdin Scientific
AVAILABLE TO ORDER
GRADE & PURITY ≥98%
Synonyms
BRD-K20979596-019-01-6 | MFCD19053214 | SCHEMBL1302286 | 3,4,5-Trimethoxy-N-(2-(3-(piperazin-1-ylmethyl)-imidazo[2,1-b]thiazol-6-yl)phenyl)benzamide | 3,4,5-trimethoxy-N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)benzamide | 3,4,5-TRIME
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
★
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1mg
S334321-1mg
3
$50.90
5mg
S334321-5mg
3
$129.90
10mg
S334321-10mg
3
$209.90
25mg
S334321-25mg
3
$314.90
50mg
S334321-50mg
2
$463.90
100mg
S334321-100mg
2
$711.90
250mg
S334321-250mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$1,443.90
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SDS
Safety data
COA
Certificate
DS
Datasheet
SP
Spec sheet
Overview Specifications Names and Identifiers Documentation Advanced Data Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solution Calculators Reviews
🧪

Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

SRT 1460 is a drug in development intendede as a small-molecule activator of sirtuin subtype SIRT1. SRT 1460 shows positive selectivity of SIRT1 versus SIRT2 and SIRT3. In animal studies, SRT 1460 was shown to have similar activity to resveratrol, a known SIRT1 activator. SRT 1460, however, is closer in potency to SRT 1720 than it is to resveratrol. SRT 1460 was observed in animal studies improving insulin sensitivity, lowering plasma glucose levels, and increasing metabolic function in mitochondria.

Specifications

Synonyms
BRD-K20979596-019-01-6 | MFCD19053214 | SCHEMBL1302286 | 3, 4, 5-Trimethoxy-N-(2-(3-(piperazin-1-ylmethyl)-imidazo[2, 1-b]thiazol-6-yl)phenyl)benzamide | 3, 4, 5-trimethoxy-N-(2-(3-(piperazin-1-ylmethyl)imidazo[2, 1-b]thiazol-6-yl)phenyl)benzamide | 3, 4, 5-TRIME
Specifications & Purity
≥98%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥98%
Names and Identifiers
Pubchem Sid504769734
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504769734
Canonical SmilesCOC1=CC(=CC(=C1OC)OC)C(=O)NC2=CC=CC=C2C3=CN4C(=CSC4=N3)CN5CCNCC5
IUPAC Name3,4,5-trimethoxy-N-[2-[3-(piperazin-1-ylmethyl)imidazo[2,1-b][1,3]thiazol-6-yl]phenyl]benzamide
InChIKeySBEWVVLMFLTQFE-UHFFFAOYSA-N
INCHI1S/C26H29N5O4S/c1-33-22-12-17(13-23(34-2)24(22)35-3)25(32)28-20-7-5-4-6-19(20)21-15-31-18(16-36-26(31)29-21)14-30-10-8-27-9-11-30/h4-7,12-13,15-16,27H,8-11,14H2,1-3H3,(H,28,32)
Isomeric SMILES COC1=CC(=CC(=C1OC)OC)C(=O)NC2=CC=CC=C2C3=CN4C(=CSC4=N3)CN5CCNCC5
PubChem CID 24180124
Molecular Weight 507.62

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Associated Targets(Human)
SIRT3 Tchem NAD-dependent deacetylase sirtuin 3 (1285 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SIRT2 Tchem NAD-dependent deacetylase sirtuin 2 (3979 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

9 results found

Lot NumberCertificate TypeDateItem
F2601061Certificate of AnalysisJun 06, 2026 S334321
E2629012Certificate of AnalysisJun 06, 2026 S334321
F2204855Certificate of AnalysisMar 04, 2025 S334321
F2204856Certificate of AnalysisMar 04, 2025 S334321
F2204857Certificate of AnalysisMar 04, 2025 S334321
F2204858Certificate of AnalysisMar 04, 2025 S334321
F2204859Certificate of AnalysisMar 04, 2025 S334321
F2204954Certificate of AnalysisMar 04, 2025 S334321
F2204956Certificate of AnalysisMar 04, 2025 S334321
Chemical and Physical Properties
Molecular Weight507.600 g/mol
XLogP33.500
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count8
Exact Mass507.194 Da
Monoisotopic Mass507.194 Da
Topological Polar Surface Area118.000 Ų
Heavy Atom Count36
Formal Charge0
Complexity714.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Solution Calculators
Reviews

Customer Reviews

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