Nifuroxazide is a nitrofuran compound inhibitor of STAT transcription factor signaling. Nifuroxazide is described to block constitutive phosphorylation of STAT3 by reducing Jak kinase autophosphorylation, decreasing the viability of myeloma cells dependin

Storage

Store at 2-8°C

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Note

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Purity

≥98%

Names and Identifiers

Pubchem Sid	504763644
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504763644
Canonical Smiles	C1=CC(=CC=C1C(=O)NN=CC2=CC=C(O2)[N+](=O)[O-])O
IUPAC Name	4-hydroxy-N-[(E)-(5-nitrofuran-2-yl)methylideneamino]benzamide
InChIKey	YCWSUKQGVSGXJO-NTUHNPAUSA-N
INCHI	1S/C12H9N3O5/c16-9-3-1-8(2-4-9)12(17)14-13-7-10-5-6-11(20-10)15(18)19/h1-7,16H,(H,14,17)/b13-7+
Isomeric SMILES	C1=CC(=CC=C1C(=O)N/N=C/C2=CC=C(O2)[N+](=O)[O-])O
WGK Germany	3
Molecular Weight	275.22
Reaxy-Rn	1352180
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1352180&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

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Advanced Data

Associated Targets(Human)

POLB Tchem DNA polymerase beta (23632 Activities)

Discover Target: POLB

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MPO Tchem Myeloperoxidase (1002 Activities)

Discover Target: MPO

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GAA Tclin Lysosomal alpha-glucosidase (35701 Activities)

Discover Target: GAA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)

Discover Target: ALDH1A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

STAT3 Tchem Signal transducer and activator of transcription 3 (3313 Activities)

Discover Target: STAT3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GLP1R Tclin Glucagon-like peptide 1 receptor (111429 Activities)

Discover Target: GLP1R

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

U2OS (164939 Activities)

Lot Number	Certificate Type	Date	Item
D2320842	Certificate of Analysis	Feb 07, 2025	N129550
D2320910	Certificate of Analysis	Feb 07, 2025	N129550
D2320925	Certificate of Analysis	Feb 07, 2025	N129550
D2320944	Certificate of Analysis	Feb 07, 2025	N129550
D2320965	Certificate of Analysis	Feb 07, 2025	N129550
D2320966	Certificate of Analysis	Feb 07, 2025	N129550
D2321155	Certificate of Analysis	Feb 07, 2025	N129550
D2321164	Certificate of Analysis	Feb 07, 2025	N129550
G1524097	Certificate of Analysis	Feb 06, 2023	N129550

Solubility	Soluble in water (practically insoluble), chloroform (practically insoluble), ethyl ether (0.01g/>100ml) (practically insoluble), Methanol (0.01g/100ml) (very slightly soluble), 1 N Sodium hydroxide (1.0g/30ml), and DMSO.
Sensitivity	Light Sensitive,Air Sensitive,Heat Sensitive
Melt Point(°C)	281-283°C
Molecular Weight	275.220 g/mol
XLogP3	2.100
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	3
Exact Mass	275.054 Da
Monoisotopic Mass	275.054 Da
Topological Polar Surface Area	121.000 Å²
Heavy Atom Count	20
Formal Charge	0
Complexity	387.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	1
Covalently-Bonded Unit Count	1

Nifuroxazide - Moligand™, ≥98% , CAS No.965-52-6

Why this grade

Storage & shipping

Quality documents

Literature proof

Overview

Specifications

Documentation

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

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