Epiblastin A - ≥98%(HPLC) , CAS No.16470-02-3

CAS: 16470-02-3 Cat. No.: E286614 Molecular Weight: 287.71

GRADE & PURITY ≥98%(HPLC)

Synonyms

6-(3-Chlorophenyl)-2,4,7-pteridinetriamine

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Specifications

Synonyms

6-(3-Chlorophenyl)-2, 4, 7-pteridinetriamine

Specifications & Purity

≥98%(HPLC)

Biochemical and Physiological Mechanisms

CK1 inhibitor (IC50values are 0.8, 3.7 and 3.8 μM for CK1δ, CK1ε and CK1α). Converts late-stage epiblast stem cells into germline-competent embryonic SC-like cells. Promotes activation and maintenance of the pluripotency network. Promotes ESC self-renewal

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥98%(HPLC)

Names and Identifiers

• Canonical Smiles: C1=CC(=CC(=C1)Cl)C2=NC3=C(N=C(N=C3N=C2N)N)N
• IUPAC Name: 6-(3-chlorophenyl)pteridine-2,4,7-triamine
• InChIKey: ZWNKKZSRANLVEW-UHFFFAOYSA-N
• INCHI: 1S/C12H10ClN7/c13-6-3-1-2-5(4-6)7-9(14)18-11-8(17-7)10(15)19-12(16)20-11/h1-4H,(H6,14,15,16,18,19,20)
• Molecular Weight: 287.71
• Reaxy-Rn: 291688
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=291688&ln=

Chemical and Physical Properties

• Solubility: Solvent:DMSO, Max Conc. mg/mL: 5.75, Max Conc. mM: 20
• Molecular Weight: 287.710 g/mol
• XLogP3: 1.600
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 1
• Exact Mass: 287.069 Da
• Monoisotopic Mass: 287.069 Da
• Topological Polar Surface Area: 130.000 Ų
• Heavy Atom Count: 20
• Formal Charge: 0
• Complexity: 344.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1