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TC-DAPK 6 - ≥98% , CAS No.315694-89-4

TC-DAPK 6 - ≥98% , CAS No.315694-89-4

Name: TC-DAPK 6 - ≥98% , CAS No.315694-89-4
Brand: Aladdin Scientific
SKU: T646454
Availability: InStock

CAS: 315694-89-4 Cat. No.: T646454 Molecular Weight: 276.29 PubChem CID: 5676111

COA

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TC-DAPK 6 - ≥98% CAS No(315694-89-4) by Aladdin Scientific

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AVAILABLE TO ORDER

GRADE & PURITY ≥98%

Synonyms

EX-A2167 | Z56820688 | EN300-260619 | AC-35960 | EN300-7536106 | 2-(2-phenylethenyl)-4-[(pyridin-3-yl)methylidene]-4,5-dihydro-1,3-oxazol-5-one | TC-DAPK-6 | (E)-4-(pyridin-3-ylmethylene)-2-((E)-styryl)oxazol-5(4H)-one | HY-15513 | 4-(pyridin-3-ylmethylen

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview Specifications Names and Identifiers Documentation Advanced Data Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solution Calculators Reviews

🧪

Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

TC-DAPK 6 is a potent, ATP-competitive, and highly selective DAPK inhibitor ( IC 50 =69 and 225 nM against DAPK1 and DAPK3 , respectively, with 10 μM ATP).

In Vitro

TC-DAPK 6 is found to be the most potent Death-associated protein kinase (DAPK) inhibitor with enzyme selectivity. When assayed with 10 μM ATP, the IC 50 values for DAPK1 and DAPK3 are 69 and 225 nM, respectively. TC-DAPK 6 also inhibits p70S6K (1 μM < IC 50 < 10 μM). MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:IC50: 69 nM (DAPK1), 225 nM (DAPK3)

Specifications

Synonyms

EX-A2167 | Z56820688 | EN300-260619 | AC-35960 | EN300-7536106 | 2-(2-phenylethenyl)-4-[(pyridin-3-yl)methylidene]-4, 5-dihydro-1, 3-oxazol-5-one | TC-DAPK-6 | (E)-4-(pyridin-3-ylmethylene)-2-((E)-styryl)oxazol-5(4H)-one | HY-15513 | 4-(pyridin-3-ylmethylen

Specifications & Purity

≥98%

Biochemical and Physiological Mechanisms

TC-DAPK 6 is a potent, ATP-competitive, and highly selective DAPK inhibitor ( IC 50 =69 and 225 nM against DAPK1 and DAPK3 , respectively, with 10 μM ATP).

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥98%

Names and Identifiers

Canonical Smiles	C1=CC=C(C=C1)C=CC2=NC(=CC3=CN=CC=C3)C(=O)O2
IUPAC Name	(4E)-2-[(E)-2-phenylethenyl]-4-(pyridin-3-ylmethylidene)-1,3-oxazol-5-one
InChIKey	GFGMISOSPOPSHN-QCTDOKRBSA-N
INCHI	1S/C17H12N2O2/c20-17-15(11-14-7-4-10-18-12-14)19-16(21-17)9-8-13-5-2-1-3-6-13/h1-12H/b9-8+,15-11+
Isomeric SMILES	C1=CC=C(C=C1)/C=C/C2=N/C(=C/C3=CN=CC=C3)/C(=O)O2
PubChem CID	5676111
Molecular Weight	276.29

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Solubility	DMSO : 18.67 mg/mL (67.57 mM; Need ultrasonic and warming)
Molecular Weight	276.290 g/mol
XLogP3	2.900
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	3
Exact Mass	276.09 Da
Monoisotopic Mass	276.09 Da
Topological Polar Surface Area	51.600 Å²
Heavy Atom Count	21
Formal Charge	0
Complexity	473.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	2
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	2
Covalently-Bonded Unit Count	1

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