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224,000+ research products · Triple ISO certified · COA & SDS available for every product · Same-day shipping on in-stock items Torcetrapib - ≥98% , Cholesteryl ester transfer protein inhibitor, CAS No.262352-17-0, Cholesteryl ester transfer protein inhibitor
Synonyms
BRD-K55675242-001-03-0 | )-carboxylate | N-2790 | CP-529414 | s2792 | TORCETRAPIB [MI] | AMY24146 | 1(2H)-Quinolinecarboxylic acid, 4-(((3,5-bis(trifluoromethyl)phenyl)methyl) (methoxycarbonyl)amino)-2-ethyl-3,4-dihydro-6-(trifluoromethyl)-, ethyl es
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Why this grade ≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview Torcetrapib is a CETP inhibitor with IC50 of 37 nM, elevates HDL-C and reduces nonHDL-C in plasma. Phase 3. A CETP inhibitor.
Specifications Synonyms
BRD-K55675242-001-03-0 | )-carboxylate | N-2790 | CP-529414 | s2792 | TORCETRAPIB [MI] | AMY24146 | 1(2H)-Quinolinecarboxylic acid, 4-(((3, 5-bis(trifluoromethyl)phenyl)methyl) (methoxycarbonyl)amino)-2-ethyl-3, 4-dihydro-6-(trifluoromethyl)-, ethyl es
Specifications & Purity
≥98%
Biochemical and Physiological Mechanisms
Inhibitor of cholesteryl ester transfer protein (CETP). Also impairs endothelial functionin vivo; induces hypertension and inhibits acetylcholine-induced vasodilation in rabbit central ear artery.
Legal Information
Sold for only research purposes
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Mechanism of action
Cholesteryl ester transfer protein inhibitor
Names and Identifiers Pubchem Sid 504757441 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504757441 Canonical Smiles CCC1CC(C2=C(N1C(=O)OCC)C=CC(=C2)C(F)(F)F)N(CC3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)C(=O)OC IUPAC Name ethyl (2R,4S)-4-[[3,5-bis(trifluoromethyl)phenyl]methyl-methoxycarbonylamino]-2-ethyl-6-(trifluoromethyl)-3,4-dihydro-2H-quinoline-1-carboxylate InChIKey CMSGWTNRGKRWGS-NQIIRXRSSA-N INCHI 1S/C26H25F9N2O4/c1-4-18-12-21(19-11-15(24(27,28)29)6-7-20(19)37(18)23(39)41-5-2)36(22(38)40-3)13-14-8-16(25(30,31)32)10-17(9-14)26(33,34)35/h6-11,18,21H,4-5,12-13H2,1-3H3/t18-,21+/m1/s1 Isomeric SMILES CC[C@@H]1C[C@@H](C2=C(N1C(=O)OCC)C=CC(=C2)C(F)(F)F)N(CC3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)C(=O)OC WGK Germany 3 Molecular Weight 600.47 Reaxy-Rn 13697133 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=13697133&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates(CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 30.02, Max Conc. mM: 50 Molecular Weight 600.500 g/mol XLogP3 7.000 Hydrogen Bond Donor Count 0 Hydrogen Bond Acceptor Count 13 Rotatable Bond Count 7 Exact Mass 600.167 Da Monoisotopic Mass 600.167 Da Topological Polar Surface Area 59.100 Ų Heavy Atom Count 41 Formal Charge 0 Complexity 889.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 2 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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