Ethyl all-trans-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoate - 10mM in DMSO, high purity , CAS No.54350-48-0, Retinoid receptor agonist

Item Number
E424634
Grouped product items
SKUSizeAvailabilityPrice Qty
E424634-1ml
1ml
Available within 8-12 weeks(?)
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$69.90

Retinoid anti-hyperplasia agent

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Compound libraries (0)

Basic Description

Synonymsetretinate | 54350-48-0 | Tegison | Ethyl etrinoate | Retinoid | Etretinato | Etretinatum | Ro 10-9359 | Tigason | CCRIS 3615 | CHEBI:4913 | Ro-109359 | HSDB 7185 | Etretinatum [INN-Latin] | Etretinato [INN-Spanish] | UNII-65M2UDR9AG | EINECS 259-119-3 | 65M2UDR9AG | NSC 297936 | NSC-297936 | e
Specifications & PurityMoligand™, 10mM in DMSO
Biochemical and Physiological MechanismsVitamin A-like hyperplasia. Avie A (Asc 2984) prodrug. Inhibits DNA synthesis in overproliferated keratinocytes.
Storage TempProtected from light,Store at -80°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeAGONIST
Mechanism of actionRetinoid receptor agonist

AI Insight

Product Properties

ALogP6.8

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name ethyl (2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate
INCHI InChI=1S/C23H30O3/c1-8-26-23(24)14-17(3)11-9-10-16(2)12-13-21-18(4)15-22(25-7)20(6)19(21)5/h9-15H,8H2,1-7H3/b11-9+,13-12+,16-10+,17-14+
InChi Key HQMNCQVAMBCHCO-DJRRULDNSA-N
Canonical SMILES CCOC(=O)C=C(C)C=CC=C(C)C=CC1=C(C(=C(C=C1C)OC)C)C
Isomeric SMILES CCOC(=O)/C=C(\C)/C=C/C=C(\C)/C=C/C1=C(C(=C(C=C1C)OC)C)C
PubChem CID 5282375
Molecular Weight 354.49

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Safety and Hazards(GHS)

Pictogram(s) GHS08,   GHS09,   GHS07
Signal Danger
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H341:Suspected of causing genetic defects

H400:Very toxic to aquatic life

H410:Very toxic to aquatic life with long lasting effects

H360:May damage fertility or the unborn child

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P273:Avoid release to the environment.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P281:Use personal protective equipment as required.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P391:Collect spillage.

P203:Obtain, read and follow all safety instructions before use.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P318:if exposed or concerned, get medical advice.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

Merck Index 3892

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