Elubrixin tosylate - 99%, high purity , CAS No.960495-43-6

Item Number

E649974

Grouped product items
SKU	Size	Availability	Price
E649974-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$250.90
E649974-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$390.90
E649974-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$820.90
E649974-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,300.90
E649974-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,950.90

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Basic Description

Synonyms	D10420 \| DTXSID60242106 \| Elubrixin tosylate (USAN) \| MS-30886 \| SB-656933-AAA \| 13FVR7WD4P \| ELUBRIXIN TOSILATE [WHO-DD] \| AKOS040758495 \| Elubrixin (tosylate) \| Elubrixin tosylate \| Urea, N-(2-chloro-3-fluorophenyl)-N'-(4-chloro-2-hydroxy-3-(1- piperazi
Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	Elubrixin tosylate (SB-656933 tosylate) is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist. Elubrixin tosylate inhibits neutrophil CD11b upregulation ( IC 50 of 260.7 nM) and shape change ( I
Storage Temp	Store at 2-8°C,Desiccated
Shipped In	Wet ice
Product Description	Elubrixin tosylate (SB-656933 tosylate) is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist. Elubrixin tosylate inhibits neutrophil CD11b upregulation ( IC 50 of 260.7 nM) and shape change ( IC 50 of 310.5 nM). Elubrixin tosylate has the potential for inflammatory diseases research, such as inflammatory bowel disease and airway inflammation In Vitro Elubrixin has an inhibitory effect on neutrophils in a dose-dependent fashion. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:CXCR2\|IL-8

Names and Identifiers

IUPAC Name	1-(2-chloro-3-fluorophenyl)-3-(4-chloro-2-hydroxy-3-piperazin-1-ylsulfonylphenyl)urea;4-methylbenzenesulfonic acid
INCHI	InChI=1S/C17H17Cl2FN4O4S.C7H8O3S/c18-10-4-5-13(23-17(26)22-12-3-1-2-11(20)14(12)19)15(25)16(10)29(27,28)24-8-6-21-7-9-24;1-6-2-4-7(5-3-6)11(8,9)10/h1-5,21,25H,6-9H2,(H2,22,23,26);2-5H,1H3,(H,8,9,10)
InChi Key	CJAUWWGOABMMJX-UHFFFAOYSA-N
Canonical SMILES	CC1=CC=C(C=C1)S(=O)(=O)O.C1CN(CCN1)S(=O)(=O)C2=C(C=CC(=C2O)NC(=O)NC3=C(C(=CC=C3)F)Cl)Cl
Isomeric SMILES	CC1=CC=C(C=C1)S(=O)(=O)O.C1CN(CCN1)S(=O)(=O)C2=C(C=CC(=C2O)NC(=O)NC3=C(C(=CC=C3)F)Cl)Cl
Alternate CAS	960495-43-6
PubChem CID	23634419
Molecular Weight	635.51

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Basic Description