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Basic Description
| Synonyms | N-(4-fluorophenyl)benzenesulfonamide | 312-63-0 | ELN484228 | 4'-fluorobenzenesulfonanilide | NSC164389 | ELN 484228 | Cambridge id 5265852 | CBDivE_015342 | CHEMBL367580 | SCHEMBL2568291 | DTXSID40304155 | BCP28956 | MFCD00091019 | s6798 | STK401855 | AKOS000383212 | N-(4-Fluoro-phenyl |
|---|---|
| Specifications & Purity | 10mM in DMSO |
| Biochemical and Physiological Mechanisms | ELN484228 is a cell penetrant α-synuclein ligand that rescues of α-synuclein induced disruption of vesicle trafficking and dopaminergic neuronal loss and neurite retraction. ELN484228 reverses a-synuclein induced impairment of phagocytosis and protects do |
| Storage Temp | Protected from light,Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | Information ELN484228 is a cell-permeable blocker that targetsα-synuclein, a key protein in Parkinson’s disease. |
AI Insight
Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Names and Identifiers
| IUPAC Name | N-(4-fluorophenyl)benzenesulfonamide |
|---|---|
| INCHI | InChI=1S/C12H10FNO2S/c13-10-6-8-11(9-7-10)14-17(15,16)12-4-2-1-3-5-12/h1-9,14H |
| InChi Key | AZORQGXJAXEIGC-UHFFFAOYSA-N |
| Canonical SMILES | C1=CC=C(C=C1)S(=O)(=O)NC2=CC=C(C=C2)F |
| Isomeric SMILES | C1=CC=C(C=C1)S(=O)(=O)NC2=CC=C(C=C2)F |
| PubChem CID | 295229 |
| Molecular Weight | 251.28 |
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Safety and Hazards(GHS)
| Pictogram(s) | GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H319:Causes serious eye irritation H302:Harmful if swallowed |
| Precautionary Statements | P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P337+P317:If eye irritation persists: Get medical help. |
| RIDADR | NONHforallmodesoftransport |