Dibasic Calcium Phosphate Dihydrate - Ph.Eur., USP, JP;Average Particle Size:~190μm, high purity , CAS No.7789-77-7

Item Number
D498388
Grouped product items
SKUSizeAvailabilityPrice Qty
D498388-500g
500g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$24.90

Basic Description

SynonymsAE-562/40879347 | Calcium hydrogenphosphate dihydrate, p.a., 98.0-105.0% | CALCIUM PHOSPHATE DIHYDRATE [WHO-DD] | DIBASIC CALCIUM PHOSPHATE HYDRATE [JAN] | brushite | CALCIUM PHOSPHATE, DIBASIC, DIHYDRATE [II] | DIBASIC CALCIUM PHOSPHATE DIHYDRATE [USP MO
Specifications & PurityPharmPure™, USP, JP, Ph.Eur., Average Particle Size:~190μm
Shipped InNormal
GradeJP, Ph.Eur., PharmPure™, USP
Product Description

Benefits:

1.Enhanced flow in powder mixtures (DC grades)

2.Ability to produce very dense and small tablets

3.Robust tablets by synergistic effects with microcrystalline cellulose

4.Less sensitive towards lubricants compared to plastically deforming materials

5.Good performance in combination with a wide variety of APIs including sticky herbal extracts

6.Acts as pH buffer in formulation with sensitive APIs

7.Perfectly suited for high-speed tableting due to low strain rate sensitivity

8.Inorganic - no risk of BSE/TSE contamination and free of allergens

9.High chemical stability, especially for anhydrous grades

10.High supply security due to multiple production sites

AI Insight

Names and Identifiers

IUPAC Name calcium;hydrogen phosphate;dihydrate
INCHI InChI=1S/Ca.H3O4P.2H2O/c;1-5(2,3)4;;/h;(H3,1,2,3,4);2*1H2/q+2;;;/p-2
InChi Key XAAHAAMILDNBPS-UHFFFAOYSA-L
Canonical SMILES O.O.OP(=O)([O-])[O-].[Ca+2]
Isomeric SMILES O.O.OP(=O)([O-])[O-].[Ca+2]
PubChem CID 104805
Molecular Weight 172.09

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

Related Documents

Reviews

Customer Reviews

Citations of This Product

1. Lei Chen, Shitong Zhang, Bo Zhang, Qian Liang, Dong Luo, Xiaojiao Yu, Binghua Yao, Kang Zhao, Zhao Yang, Yufei Tang, Zixiang Wu.  (2023)  Study on the poly(methyl methacrylate-acrylic acid)/calcium phosphate cement composite bound by chelation with enhanced water absorption and biomechanical properties.  Journal of the Mechanical Behavior of Biomedical Materials,  147  (6): (106149).  [PMID:37782989] [10.1016/j.jmbbm.2023.106149]
2. Fupo He, Jin Rao, Wenhao Fu, Jielin Zhou, Yuxuan Zhang, Tengyun Chen, Wenhao Huang, Yao Wang, Teliang Lu, Haishan Shi.  (2023)  3D printing and physicochemical and biological characterizations of gallium-containing magnesium/calcium phosphate ceramic scaffolds.  CERAMICS INTERNATIONAL,      [PMID:] [10.1016/j.ceramint.2023.08.127]
3. Tao Zhou-Shan, Li Tian-Lin, Wei Shan.  (2023)  Co-modified 3D printed β-tricalcium phosphate with magnesium and selenium promotes bone defect regeneration in ovariectomized rat.  JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE,  34  (1): (1-14).  [PMID:36622473] [10.1007/s10856-022-06708-w]
4. Min Wei, Yufei Tang, Lei Chen, Bo Zhang, Shitong Zhang, Kang Zhao, Zixiang Wu.  (2022)  Enhanced mechanical properties and anti-washout of calcium phosphate cement/montmorillonite composite bone-cement for bone-repair applications.  CERAMICS INTERNATIONAL,  48  (35185).  [PMID:] [10.1016/j.ceramint.2022.08.117]
5. Hongwei Chen, Changchang Lv, Lin Guo, Ming Ma, Xiangfeng Li, Zhengyi Lan, Jun Huo, Hao Dong, Xiangdong Zhu, Qiang Zhu, Yuming Gu, Ziteng Liu, Jianjun Liu, Hangrong Chen, Xuefeng Guo, Jing Ma.  (2022)  Surface Stability and Morphology of Calcium Phosphate Tuned by pH Values and Lactic Acid Additives: Theoretical and Experimental Study.  ACS Applied Materials & Interfaces,  14  (4): (4836–4851).  [PMID:35043625] [10.1021/acsami.1c18727]
6. Teliang Lu, Shenglei Feng, Fupo He, Jiandong Ye.  (2019)  Enhanced osteogenesis of honeycomb β-tricalcium phosphate scaffold by construction of interconnected pore structure: An in vivo study.  JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A,  108  (3): (645-653).  [PMID:31747100] [10.1002/jbm.a.36844]
7. Gu Yifan, Zhang Jing, Zhang Xinzhi, Liang Guiping, Xu Tao, Niu Wei.  (2019)  Three-dimensional Printed Mg-Doped β-TCP Bone Tissue Engineering Scaffolds: Effects of Magnesium Ion Concentration on Osteogenesis and Angiogenesis In Vitro.  Tissue Engineering and Regenerative Medicine,  16  (4): (415-429).  [PMID:31413945] [10.1007/s13770-019-00192-0]
8. Guowen Qian, Xingmei Li, Fupo He, Jiandong Ye.  (2019)  Improving the anti-washout property of calcium phosphate cement by introducing konjac glucomannan/κ-carrageenan blend.  JOURNAL OF BIOMATERIALS APPLICATIONS,      [PMID:30661443] [10.1177/0885328218824762]
9. Qian Guowen, Li Xingmei, He Fupo, Ye Jiandong.  (2018)  Improvement of anti-washout property of calcium phosphate cement by addition of konjac glucomannan and guar gum.  JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE,  29  (12): (1-11).  [PMID:30511166] [10.1007/s10856-018-6193-7]
10. Shenglei Feng, Fupo He, Jiandong Ye.  (2017)  Fabrication and characterization of honeycomb β-tricalcium phosphate scaffolds through an extrusion technique.  CERAMICS INTERNATIONAL,  43  (6778).  [PMID:] [10.1016/j.ceramint.2017.02.094]
11. Ming Wang, Liping Wang, Chao Shi, Tian Sun, Yi Zeng, Yingchun Zhu.  (2016)  The crystal structure and chemical state of aluminum-doped hydroxyapatite by experimental and first principles calculation studies.  PHYSICAL CHEMISTRY CHEMICAL PHYSICS,  18  (31): (21789-21796).  [PMID:27436334] [10.1039/C6CP03230C]
12. Peng Wang, Pengzheng Liu, Haitao Peng, Xiaoman Luo, Huipin Yuan, Juncai Zhang, Yonggang Yan.  (2016)  Biocompatibility evaluation of dicalcium phosphate/calcium sulfate/poly (amino acid) composite for orthopedic tissue engineering in vitro and in vivo.  JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION,  27  (11): (1170-1186).  [PMID:27126299] [10.1080/09205063.2016.1184123]
13. Xiu Yan Ren, Zhe Yu, Baijun Liu, Xue Jiao Liu, Ya Jun Wang, Qiang Su, Guang Hui Gao.  (2016)  Highly tough and puncture resistant hydrogels driven by macromolecular microspheres.  RSC Advances,  (11): (8956-8963).  [PMID:] [10.1039/C5RA24778K]

References

1. Lei Chen, Shitong Zhang, Bo Zhang, Qian Liang, Dong Luo, Xiaojiao Yu, Binghua Yao, Kang Zhao, Zhao Yang, Yufei Tang, Zixiang Wu.  (2023)  Study on the poly(methyl methacrylate-acrylic acid)/calcium phosphate cement composite bound by chelation with enhanced water absorption and biomechanical properties.  Journal of the Mechanical Behavior of Biomedical Materials,  147  (6): (106149).  [PMID:37782989] [10.1016/j.jmbbm.2023.106149]
2. Fupo He, Jin Rao, Wenhao Fu, Jielin Zhou, Yuxuan Zhang, Tengyun Chen, Wenhao Huang, Yao Wang, Teliang Lu, Haishan Shi.  (2023)  3D printing and physicochemical and biological characterizations of gallium-containing magnesium/calcium phosphate ceramic scaffolds.  CERAMICS INTERNATIONAL,      [PMID:] [10.1016/j.ceramint.2023.08.127]
3. Tao Zhou-Shan, Li Tian-Lin, Wei Shan.  (2023)  Co-modified 3D printed β-tricalcium phosphate with magnesium and selenium promotes bone defect regeneration in ovariectomized rat.  JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE,  34  (1): (1-14).  [PMID:36622473] [10.1007/s10856-022-06708-w]
4. Min Wei, Yufei Tang, Lei Chen, Bo Zhang, Shitong Zhang, Kang Zhao, Zixiang Wu.  (2022)  Enhanced mechanical properties and anti-washout of calcium phosphate cement/montmorillonite composite bone-cement for bone-repair applications.  CERAMICS INTERNATIONAL,  48  (35185).  [PMID:] [10.1016/j.ceramint.2022.08.117]
5. Hongwei Chen, Changchang Lv, Lin Guo, Ming Ma, Xiangfeng Li, Zhengyi Lan, Jun Huo, Hao Dong, Xiangdong Zhu, Qiang Zhu, Yuming Gu, Ziteng Liu, Jianjun Liu, Hangrong Chen, Xuefeng Guo, Jing Ma.  (2022)  Surface Stability and Morphology of Calcium Phosphate Tuned by pH Values and Lactic Acid Additives: Theoretical and Experimental Study.  ACS Applied Materials & Interfaces,  14  (4): (4836–4851).  [PMID:35043625] [10.1021/acsami.1c18727]
6. Teliang Lu, Shenglei Feng, Fupo He, Jiandong Ye.  (2019)  Enhanced osteogenesis of honeycomb β-tricalcium phosphate scaffold by construction of interconnected pore structure: An in vivo study.  JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A,  108  (3): (645-653).  [PMID:31747100] [10.1002/jbm.a.36844]
7. Gu Yifan, Zhang Jing, Zhang Xinzhi, Liang Guiping, Xu Tao, Niu Wei.  (2019)  Three-dimensional Printed Mg-Doped β-TCP Bone Tissue Engineering Scaffolds: Effects of Magnesium Ion Concentration on Osteogenesis and Angiogenesis In Vitro.  Tissue Engineering and Regenerative Medicine,  16  (4): (415-429).  [PMID:31413945] [10.1007/s13770-019-00192-0]
8. Guowen Qian, Xingmei Li, Fupo He, Jiandong Ye.  (2019)  Improving the anti-washout property of calcium phosphate cement by introducing konjac glucomannan/κ-carrageenan blend.  JOURNAL OF BIOMATERIALS APPLICATIONS,      [PMID:30661443] [10.1177/0885328218824762]
9. Qian Guowen, Li Xingmei, He Fupo, Ye Jiandong.  (2018)  Improvement of anti-washout property of calcium phosphate cement by addition of konjac glucomannan and guar gum.  JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE,  29  (12): (1-11).  [PMID:30511166] [10.1007/s10856-018-6193-7]
10. Shenglei Feng, Fupo He, Jiandong Ye.  (2017)  Fabrication and characterization of honeycomb β-tricalcium phosphate scaffolds through an extrusion technique.  CERAMICS INTERNATIONAL,  43  (6778).  [PMID:] [10.1016/j.ceramint.2017.02.094]
11. Ming Wang, Liping Wang, Chao Shi, Tian Sun, Yi Zeng, Yingchun Zhu.  (2016)  The crystal structure and chemical state of aluminum-doped hydroxyapatite by experimental and first principles calculation studies.  PHYSICAL CHEMISTRY CHEMICAL PHYSICS,  18  (31): (21789-21796).  [PMID:27436334] [10.1039/C6CP03230C]
12. Peng Wang, Pengzheng Liu, Haitao Peng, Xiaoman Luo, Huipin Yuan, Juncai Zhang, Yonggang Yan.  (2016)  Biocompatibility evaluation of dicalcium phosphate/calcium sulfate/poly (amino acid) composite for orthopedic tissue engineering in vitro and in vivo.  JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION,  27  (11): (1170-1186).  [PMID:27126299] [10.1080/09205063.2016.1184123]
13. Xiu Yan Ren, Zhe Yu, Baijun Liu, Xue Jiao Liu, Ya Jun Wang, Qiang Su, Guang Hui Gao.  (2016)  Highly tough and puncture resistant hydrogels driven by macromolecular microspheres.  RSC Advances,  (11): (8956-8963).  [PMID:] [10.1039/C5RA24778K]

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