Dapiprazole hydrochloride - ≥98%, high purity , Alpha-1a adrenergic receptor antagonist, CAS No.72822-13-0, Alpha-1a adrenergic receptor antagonist

Item Number

D275147

Grouped product items
SKU	Size	Availability	Price
D275147-10mg	10mg	4	$53.90
D275147-25mg	25mg	4	$107.90
D275147-50mg	50mg	3	$165.90
D275147-100mg	100mg	2	$246.90
D275147-250mg	250mg	2	$555.90
D275147-500mg	500mg	2	$1,000.90

Selective α 1 -adrenoreceptor antagonist

View related series

Basic Description

Synonyms	AKOS000119855 \| CAS-72822-13-0 \| DAPIPRAZOLE HYDROCHLORIDE [ORANGE BOOK] \| DAPIPRAZOLE HYDROCHLORIDE [MART.] \| 3-(2-(4-o-tolylpiperazin-1-yl)ethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridine hydrochloride \| 5,6,7,8-Tetrahydro-3-[2-(4-O-tolyl-1-pipe
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	Selective α 1 -adrenoreceptor antagonist. Shows 10-fold selectivey for A and D subtypes over B subtype. Antipsychotic agent. Active in vivo and in vitro .
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Action Type	ANTAGONIST
Mechanism of action	Alpha-1a adrenergic receptor antagonist
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Names and Identifiers

Pubchem Sid	488195872
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488195872
IUPAC Name	3-[2-[4-(2-methylphenyl)piperazin-1-yl]ethyl]-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridine;hydrochloride
INCHI	InChI=1S/C19H27N5.ClH/c1-16-6-2-3-7-17(16)23-14-12-22(13-15-23)11-9-19-21-20-18-8-4-5-10-24(18)19;/h2-3,6-7H,4-5,8-15H2,1H3;1H
InChi Key	ZIODNPFQZIHCOE-UHFFFAOYSA-N
Canonical SMILES	CC1=CC=CC=C1N2CCN(CC2)CCC3=NN=C4N3CCCC4.Cl
Isomeric SMILES	CC1=CC=CC=C1N2CCN(CC2)CCC3=NN=C4N3CCCC4.Cl
PubChem CID	6917787
Molecular Weight	361.91

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

12 results found

Lot Number	Certificate Type	Date	Item
F2315731	Certificate of Analysis	May 09, 2024	D275147
F2315748	Certificate of Analysis	Mar 22, 2024	D275147
F2315839	Certificate of Analysis	Mar 22, 2024	D275147
F2315841	Certificate of Analysis	Mar 22, 2024	D275147
F2315844	Certificate of Analysis	Mar 22, 2024	D275147
F2315875	Certificate of Analysis	Mar 22, 2024	D275147
F2316349	Certificate of Analysis	Mar 22, 2024	D275147
F2316339	Certificate of Analysis	Mar 07, 2024	D275147
F2315882	Certificate of Analysis	Mar 07, 2024	D275147
F2316348	Certificate of Analysis	Mar 07, 2024	D275147
F2315745	Certificate of Analysis	Mar 07, 2024	D275147
F2315729	Certificate of Analysis	Mar 07, 2024	D275147

References

1. Soltani A et al.. (2021) Is an Immunosuppressive Microenvironment a Characteristic of Both Intra- and Extraparenchymal Central Nervous Tumors?. Pathophysiology, 28 (34-49). [PMID:35366268]
2. Jaromi L et al.. (2021) KRAS and EGFR Mutations Differentially Alter ABC Drug Transporter Expression in Cisplatin-Resistant Non-Small Cell Lung Cancer.. Int J Mol Sci, 22 (10): [PMID:34065402]
3. Abdelwahab EMM et al.. (2019) Wnt signaling regulates trans-differentiation of stem cell like type 2 alveolar epithelial cells to type 1 epithelial cells.. Respir Res, 20 (204). [PMID:31492143]

Solution Calculators

Determine the necessary mass, volume, or concentration for preparing a solution.

Determine the dilution needed to prepare a stock solution.

Basic Description