| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| F111301-1g | 1g | 3 | $80.90 | |
| F111301-5g | 5g | 3 | $194.90 | |
| F111301-25g | 25g | 3 | $876.90 | |
| F111301-100g | 100g | 3 | $3,154.90 |
Common metabolic sugar.
| Synonyms | D-Fructose, 1,6-bis(dihydrogen phosphate), sodium salt (1:3) | D-Fructose-1,6-diphosphate trisodium salt octahydrate | Diphosphofructose trisodium | Fosfructose (trisodium) | Esafosfan trisodium | MFCD00135872 | sodium (2R,3R,4S)-6-(hydrogenphosphonatooxy |
|---|---|
| Specifications & Purity | ≥98% |
| Biochemical and Physiological Mechanisms | Common metabolic sugar. Precursor of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate in the glycolytic pathway. Allosteric activator of enzymes such as pyruvate kinase and NAD + -dependent L-(+)-lactate dehydrogenase. |
| Storage Temp | Store at 2-8°C |
| Shipped In | Wet ice |
| Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
| Pubchem Sid | 504756224 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504756224 |
| IUPAC Name | trisodium;[(2R,3R,4S)-2,3,4-trihydroxy-6-[hydroxy(oxido)phosphoryl]oxy-5-oxohexyl] phosphate |
| INCHI | InChI=1S/C6H14O12P2.3Na/c7-3(1-17-19(11,12)13)5(9)6(10)4(8)2-18-20(14,15)16;;;/h3,5-7,9-10H,1-2H2,(H2,11,12,13)(H2,14,15,16);;;/q;3*+1/p-3/t3-,5-,6-;;;/m1.../s1 |
| InChi Key | CEHGLSKJDFICTB-PWVOXRODSA-K |
| Canonical SMILES | C(C(C(C(C(=O)COP(=O)(O)[O-])O)O)O)OP(=O)([O-])[O-].[Na+].[Na+].[Na+] |
| Isomeric SMILES | C([C@H]([C@H]([C@@H](C(=O)COP(=O)(O)[O-])O)O)O)OP(=O)([O-])[O-].[Na+].[Na+].[Na+] |
| Alternate CAS | 488-69-7 |
| PubChem CID | 94482 |
| Molecular Weight | 406.06(anhydrous basis) |
| 1. Ai Yuan-li, Wang Wei-jia, Liu Fan-jian, Fang Wei, Chen Hang-zi, Wu Liu-zheng, Hong Xuehui, Zhu Yuekun, Zhang Ci-xiong, Liu Long-yu, Hong Wen-bin, Zhou Bo, Chen Qi-tao, Wu Qiao. (2023) Mannose antagonizes GSDME-mediated pyroptosis through AMPK activated by metabolite GlcNAc-6P. CELL RESEARCH, (1-19). [PMID:37460805] [10.1038/s41422-023-00848-6] |
| 2. Nkoh Jackson Nkoh, He Xian, Lu Hai-long, Li Ke-wei, Shi Ren-yong, Li Jiu-yu, Xu Ren-kou. (2022) Chitosan and D-fructose 1,6-bisphosphate differ in their effects on soil acidity and aluminum activation. JOURNAL OF SOILS AND SEDIMENTS, 22 (8): (2129-2145). [PMID:] [10.1007/s11368-022-03228-6] |
| 3. Mei He, Ma Yange, Wu Huimin, Wang Xuedong. (2021) Fluorescent and visual assay of H2O2 and glucose based on a highly sensitive copper nanoclusters-Ce(III) fluoroprobe. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 413 (8): (2135-2146). [PMID:33511458] [10.1007/s00216-021-03181-2] |
| 4. Li Zhiyang, Xiao Xilin, Su Changlin, Hu Nan, Nie Changming, Liu Yong, Zhang Di, Wang Zhimei, Liao Lifu. (2020) Synthesis of bipolar tetradentate ligand and determination of fructose 1,6-diphosphate by resonance light scattering of its supramolecular polymer. JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY, 323 (1): (431-438). [PMID:] [10.1007/s10967-019-06947-2] |
| 5. Jinling Cui, Mingzhu Yan, Xiaoyi Liu, Shutao Yin, Shangyun Lu, Lihong Fan, Hongbo Hu. (2019) Inorganic Selenium Induces Nonapoptotic Programmed Cell Death in PC-3 Prostate Cancer Cells Associated with Inhibition of Glycolysis. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 67 (38): (10637–10645). [PMID:31513389] [10.1021/acs.jafc.9b03875] |
| 6. Mingxiu Guan, Yingna Tong, Xiaobin Liu, Dong Dong, Yunli Zhou. (2017) Enzyme Kinetic Assay to Measure the Activity of Tumor M2 Pyruvate Kinase in Breast Cancer Patients. ANNALS OF CLINICAL AND LABORATORY SCIENCE, 47 (6): (676-686). [PMID:29263041] [PMID:29263041] |
| 7. Lian-Hua Fu, Yan-Jun Liu, Ming-Guo Ma, Xue-Ming Zhang, Zhi-Min Xue, Jie-Fang Zhu. (2016) Microwave-Assisted Hydrothermal Synthesis of Cellulose/Hydroxyapatite Nanocomposites. Polymers, 8 (9): (316). [PMID:30974621] [10.3390/polym8090316] |
| 8. Jin C et al.. (2020) Perturbation of phosphoglycerate kinase 1 (PGK1) only marginally affects glycolysis in cancer cells.. J Biol Chem, 295 (19): (6425-6446). [PMID:32217690] |
| 1. Ai Yuan-li, Wang Wei-jia, Liu Fan-jian, Fang Wei, Chen Hang-zi, Wu Liu-zheng, Hong Xuehui, Zhu Yuekun, Zhang Ci-xiong, Liu Long-yu, Hong Wen-bin, Zhou Bo, Chen Qi-tao, Wu Qiao. (2023) Mannose antagonizes GSDME-mediated pyroptosis through AMPK activated by metabolite GlcNAc-6P. CELL RESEARCH, (1-19). [PMID:37460805] [10.1038/s41422-023-00848-6] |
| 2. Nkoh Jackson Nkoh, He Xian, Lu Hai-long, Li Ke-wei, Shi Ren-yong, Li Jiu-yu, Xu Ren-kou. (2022) Chitosan and D-fructose 1,6-bisphosphate differ in their effects on soil acidity and aluminum activation. JOURNAL OF SOILS AND SEDIMENTS, 22 (8): (2129-2145). [PMID:] [10.1007/s11368-022-03228-6] |
| 3. Mei He, Ma Yange, Wu Huimin, Wang Xuedong. (2021) Fluorescent and visual assay of H2O2 and glucose based on a highly sensitive copper nanoclusters-Ce(III) fluoroprobe. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 413 (8): (2135-2146). [PMID:33511458] [10.1007/s00216-021-03181-2] |
| 4. Li Zhiyang, Xiao Xilin, Su Changlin, Hu Nan, Nie Changming, Liu Yong, Zhang Di, Wang Zhimei, Liao Lifu. (2020) Synthesis of bipolar tetradentate ligand and determination of fructose 1,6-diphosphate by resonance light scattering of its supramolecular polymer. JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY, 323 (1): (431-438). [PMID:] [10.1007/s10967-019-06947-2] |
| 5. Jinling Cui, Mingzhu Yan, Xiaoyi Liu, Shutao Yin, Shangyun Lu, Lihong Fan, Hongbo Hu. (2019) Inorganic Selenium Induces Nonapoptotic Programmed Cell Death in PC-3 Prostate Cancer Cells Associated with Inhibition of Glycolysis. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 67 (38): (10637–10645). [PMID:31513389] [10.1021/acs.jafc.9b03875] |
| 6. Mingxiu Guan, Yingna Tong, Xiaobin Liu, Dong Dong, Yunli Zhou. (2017) Enzyme Kinetic Assay to Measure the Activity of Tumor M2 Pyruvate Kinase in Breast Cancer Patients. ANNALS OF CLINICAL AND LABORATORY SCIENCE, 47 (6): (676-686). [PMID:29263041] [PMID:29263041] |
| 7. Lian-Hua Fu, Yan-Jun Liu, Ming-Guo Ma, Xue-Ming Zhang, Zhi-Min Xue, Jie-Fang Zhu. (2016) Microwave-Assisted Hydrothermal Synthesis of Cellulose/Hydroxyapatite Nanocomposites. Polymers, 8 (9): (316). [PMID:30974621] [10.3390/polym8090316] |
| 8. Jin C et al.. (2020) Perturbation of phosphoglycerate kinase 1 (PGK1) only marginally affects glycolysis in cancer cells.. J Biol Chem, 295 (19): (6425-6446). [PMID:32217690] |
A2205667