Corylifol A - 99%, high purity , CAS No.775351-88-7

Item Number

C648628

Grouped product items
SKU	Size	Availability	Price
C648628-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$78.90
C648628-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$165.90
C648628-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$275.90

Flavonoids Isoflavones Phenols Polyphenols

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Basic Description

Synonyms	AKOS032948982 \| MS-26509 \| 3-[3-[(2E)-3,7-dimethylocta-2,6-dienyl]-4-hydroxyphenyl]-7-hydroxychromen-4-one \| Corylinin \| 3'-Geranyl-4',7-dihydroxyisoflavone \| BCP18858 \| AC-34049 \| HY-N0897 \| DTXSID401345950 \| SCHEMBL23028385 \| CS-3753 \| Corylifol A
Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	Corylifol A inhibits IL-6-induced STAT3 activation and phosphorylation, with an IC 50 of 0.81 μM.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	Corylifol A inhibits IL-6-induced STAT3 activation and phosphorylation, with an IC 50 of 0.81 μM. In Vitro Corylifol A shows an inhibitory effect on IL-6-induced STAT3 promoter activity in Hep3B cells with IC 50 value of 0.81±0.15 μM, also inhibits STAT3 phosphorylation induced by IL-6 in Hep3B cells. Corylifol A inhibits SARA PLpro in a dose-dependent manner with IC 50 s ranging between 4.2 and 38.4 μM. Corylifol A is found to be a naturally occurring potent inhibitor of hCE2, with low K i values ranging from 0.62 μM to 3.89 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:STAT3 0.81 μM (IC 50 )

Names and Identifiers

IUPAC Name	3-[3-[(2E)-3,7-dimethylocta-2,6-dienyl]-4-hydroxyphenyl]-7-hydroxychromen-4-one
INCHI	InChI=1S/C25H26O4/c1-16(2)5-4-6-17(3)7-8-19-13-18(9-12-23(19)27)22-15-29-24-14-20(26)10-11-21(24)25(22)28/h5,7,9-15,26-27H,4,6,8H2,1-3H3/b17-7+
InChi Key	ZBHUUXLHDOUMKM-REZTVBANSA-N
Canonical SMILES	CC(=CCCC(=CCC1=C(C=CC(=C1)C2=COC3=C(C2=O)C=CC(=C3)O)O)C)C
Isomeric SMILES	CC(=CCC/C(=C/CC1=C(C=CC(=C1)C2=COC3=C(C2=O)C=CC(=C3)O)O)/C)C
Alternate CAS	775351-88-7
PubChem CID	25056407
MeSH Entry Terms	corylifol A
Molecular Weight	390.47

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Basic Description