bedaquiline - 97%, high purity , CAS No.843663-66-1

Item Number

B177578

Grouped product items
SKU	Size	Availability	Price
B177578-5mg	5mg	3	$14.90
B177578-25mg	25mg	3	$49.90
B177578-100mg	100mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$139.90
B177578-500mg	500mg	2	$469.90
B177578-1g	1g	2	$799.90

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Basic Description

Synonyms	(alphaR,betaS)-rel-Bedaquiline \| NCGC00348215-04 \| (1R,2S)-1-(6-BROMO-2-METHOXYQUINOLIN-3-YL)-4-(DIMETHYLAMINO)-2-(NAPHTHALEN-1-YL)-1- PHENYLBUTAN-2-OL \| cis-1-(6-Bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol \| D09
Specifications & Purity	Moligand™, ≥97%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Product Description	Bedaquiline (R207910) is an anti-tuberculosis drug which selectively inhibit the mycobacterial energy metabolism i.e. ATP synthesis and found to be effective against all states of Mycobacterium tuberculosis.

Names and Identifiers

Pubchem Sid	504763814
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504763814
IUPAC Name	(1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-naphthalen-1-yl-1-phenylbutan-2-ol
INCHI	InChI=1S/C32H31BrN2O2/c1-35(2)19-18-32(36,28-15-9-13-22-10-7-8-14-26(22)28)30(23-11-5-4-6-12-23)27-21-24-20-25(33)16-17-29(24)34-31(27)37-3/h4-17,20-21,30,36H,18-19H2,1-3H3/t30-,32-/m1/s1
InChi Key	QUIJNHUBAXPXFS-XLJNKUFUSA-N
Canonical SMILES	CN(C)CCC(C1=CC=CC2=CC=CC=C21)(C(C3=CC=CC=C3)C4=C(N=C5C=CC(=CC5=C4)Br)OC)O
Isomeric SMILES	CN(C)CC[C@@](C1=CC=CC2=CC=CC=C21)([C@H](C3=CC=CC=C3)C4=C(N=C5C=CC(=CC5=C4)Br)OC)O
PubChem CID	5388906
Molecular Weight	555.516

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

13 results found

Lot Number	Certificate Type	Date	Item
B2510179	Certificate of Analysis	Dec 09, 2024	B177578
B2510180	Certificate of Analysis	Dec 09, 2024	B177578
B2510181	Certificate of Analysis	Dec 09, 2024	B177578
B2510189	Certificate of Analysis	Dec 09, 2024	B177578
B2510192	Certificate of Analysis	Dec 09, 2024	B177578
I2109246	Certificate of Analysis	Jun 06, 2024	B177578
I2109261	Certificate of Analysis	Jun 06, 2024	B177578
I2109262	Certificate of Analysis	Jun 06, 2024	B177578
J2213302	Certificate of Analysis	Jul 27, 2022	B177578
J2213303	Certificate of Analysis	Jul 27, 2022	B177578
J2213343	Certificate of Analysis	Jul 27, 2022	B177578
J2213348	Certificate of Analysis	Jul 27, 2022	B177578
J2213349	Certificate of Analysis	Jul 27, 2022	B177578

Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS08, GHS09
Signal	Danger
Hazard Statements	H301:Toxic if swallowed H373:Causes damage to organs through prolonged or repeated exposure H400:Very toxic to aquatic life H410:Very toxic to aquatic life with long lasting effects
Precautionary Statements	P273:Avoid release to the environment. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P270:Do not eat, drink or smoke when using this product. P391:Collect spillage. P330:Rinse mouth. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P319:Get medical help if you feel unwell.

References

1. Koul A, Dendouga N, Vergauwen K, Molenberghs B, Vranckx L, Willebrords R, Ristic Z, Lill H, Dorange I, Guillemont J et al.. (2007) Diarylquinolines target subunit c of mycobacterial ATP synthase.. Nat Chem Biol, 3 (6): (323-4). [PMID:17496888] [10.1021/op500134e]
2. Villemagne B, Crauste C, Flipo M, Baulard AR, Déprez B, Willand N. (2012) Tuberculosis: the drug development pipeline at a glance.. Eur J Med Chem, 51 (13): (1-16). [PMID:22421275] [10.1021/op500134e]

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Basic Description