| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| N303921-250mg | 250mg | 4 | $68.90 | |
| N303921-1g | 1g | 1 | $171.90 | |
| N303921-5g | 5g | 1 | $515.90 | |
| N303921-25g | 25g | 1 | $1,716.90 |
| Synonyms | Coenzyme II | NADP | TPN | BRN 3885115 | nicotinamide adenine dinucleotide phosphate | SCHEMBL7869 | TPN-ox | nadp nicotinamide-adenine-dinucleotide phosphate | 944A1E1D-E8B9-42AF-B61D-7C4242AB099A | Adenosine 5'-(trihydrogen diphosphate), 2'-(dihydrogen |
|---|---|
| Specifications & Purity | Moligand™, ≥90% |
| Biochemical and Physiological Mechanisms | β-nicotinamide adenine dinucleotide 2 ′-phosphate (NADP+) and β-nicotinamide adenine dinucleotide 2 ′-phosphate reduction (NADPH) form a coenzyme redox pair (NADP+:NADPH), which participates in a wide range of enzyme-catalyzed redox reactions. NADP+/NADPH |
| Storage Temp | Store at -20°C |
| Shipped In | Ice chest + Ice pads |
| Grade | Moligand™ |
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| Pubchem Sid | 488179953 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488179953 |
| IUPAC Name | [[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-4-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate |
| INCHI | InChI=1S/C21H28N7O17P3/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32/h1-4,7-8,10-11,13-16,20-21,29-31H,5-6H2,(H7-,22,23,24,25,32,33,34,35,36,37,38,39)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1 |
| InChi Key | XJLXINKUBYWONI-NNYOXOHSSA-N |
| Canonical SMILES | C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)([O-])OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)OP(=O)(O)O)O)O)O)C(=O)N |
| Isomeric SMILES | C1=CC(=C[N+](=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)([O-])OP(=O)(O)OC[C@@H]3[C@H]([C@H]([C@@H](O3)N4C=NC5=C(N=CN=C54)N)OP(=O)(O)O)O)O)O)C(=O)N |
| PubChem CID | 5885 |
| Molecular Weight | 743.41 |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 A2215527 | Certificate of Analysis | Nov 05, 2024 | N303921 |
| H2322301 | Certificate of Analysis | Aug 03, 2023 | N303921 |
| A2508131 | Certificate of Analysis | Aug 03, 2023 | N303921 |
| H2322300 | Certificate of Analysis | Aug 03, 2023 | N303921 |
| H2322299 | Certificate of Analysis | Aug 03, 2023 | N303921 |
| H2322298 | Certificate of Analysis | Aug 03, 2023 | N303921 |
| A2330460 | Certificate of Analysis | Feb 01, 2023 | N303921 |
| A2215490 | Certificate of Analysis | Jan 06, 2022 | N303921 |
| I2405019 | Certificate of Analysis | Jan 06, 2022 | N303921 |
| G2320158 | Certificate of Analysis | Jan 06, 2022 | N303921 |
| F2314491 | Certificate of Analysis | Jan 06, 2022 | N303921 |
| A2215491 | Certificate of Analysis | Jan 06, 2022 | N303921 |
| A2215489 | Certificate of Analysis | Jan 06, 2022 | N303921 |
| D2313986 | Certificate of Analysis | Aug 06, 2021 | N303921 |
| D2314016 | Certificate of Analysis | Aug 06, 2021 | N303921 |
| D2314061 | Certificate of Analysis | Aug 06, 2021 | N303921 |
| D2313924 | Certificate of Analysis | Aug 06, 2021 | N303921 |
| D2313923 | Certificate of Analysis | Aug 06, 2021 | N303921 |
| D2313922 | Certificate of Analysis | Aug 06, 2021 | N303921 |
| D23131112 | Certificate of Analysis | Aug 06, 2021 | N303921 |
| D23131061 | Certificate of Analysis | Aug 06, 2021 | N303921 |
| Pictogram(s) | GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
| Merck Index | 6348 |
Starting at $32.90
| 1. Huang Mingjun, Wu Fanchang, Zuo Xue, Liu Jinman, Yu Wenqian, Xie Ruiye, Liu Guoqing, Tan Qiwen, Wang Qi, Liang Yong. (2023) Quercetin Simultaneously Inhibited Cytochrome P450 and P-Glycoprotein to Improve the Pharmacokinetics of Osthole in Rat Plasma. Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy, (27): (1-10). [PMID:22134922] [10.1007/s43450-023-00487-3] |
| 2. Lai Liang, Zhang Mengyun, Liu Chusheng, Qu Jiahuan, Xu Dongsheng, Jiang Zhengjin. (2023) A comprehensive evaluation of a polymeric zwitterionic hydrophilic monolith for nucleotide separation. ANALYTICAL SCIENCES, (1-7). [PMID:37843729] [10.1007/s44211-023-00430-5] |
| 3. Yan Shi, Wei Xu, Dawei Ni, Wenli Zhang, Cuie Guang, Wanmeng Mu. (2024) Identification and application of a novel deoxynivalenol-degrading enzyme from Youhaiella tibetensis. FOOD CHEMISTRY, 435 (137609). [PMID:37783127] [10.1016/j.foodchem.2023.137609] |
| 4. Jiang Zhu, Ruinan Qu, Yawei Wang, Ruoyao Ni, Kai Tian, Chan Yang, Mei Li, Michael Kristensen, Xinghui Qiu. (2023) Up-regulation of CYP6G4 mediated by a CncC/maf binding-site-containing insertion confers resistance to multiple classes of insecticides in the house fly Musca domestica. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 253 (28): (127024). [PMID:37769776] [10.1016/j.ijbiomac.2023.127024] |
| 5. Nawaz Muhammad, Jiang Yipeng, Xiao Ying, Yu Hao, Wang Zikang, Hu Kun, Zhang Tianao, Hu Jiajun, Gao Min-Tian. (2023) Influence of Different Pretreatment Steps on the Ratio of Phenolic Compounds to Saccharides in Soluble Polysaccharides Derived from Rice Straw and Their Effect on Ethanol Fermentation. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 195 (7): (4552-4569). [PMID:36701092] [10.1007/s12010-023-04337-9] |
| 6. Zhongzhong Lu, Jincong Yan, Mingsheng Xu, Lina Sun, Jihuan Liu, Ye Zhang, Lei Shi, Xifeng Fei, Yi Cao, Renjun Pei. (2023) Hypoxia-Responsive Aggregation of Iron Oxide Nanoparticles for T1-to-T2 Switchable Magnetic Resonance Imaging of Tumors. ACS Applied Nano Materials, 6 (1): (119–130). [PMID:] [10.1021/acsanm.2c03850] |
| 7. Jiang Zhu, Jing Feng, Kai Tian, Chong Li, Mei Li, Xinghui QIU. (2022) Functional characterization of CYP6G4 from the house fly in propoxur metabolism and resistance. PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 187 (105186). [PMID:36127048] [10.1016/j.pestbp.2022.105186] |
| 8. Xinxing Gao, Qianqian Pei, Nianqing Zhu, Yi Mou, Jilei Liang, Xin Zhang, Shoushuai Feng. (2022) Efficient Asymmetric Synthesis of (S)-N-Boc-3-hydroxypiperidine by Coexpressing Ketoreductase and Glucose Dehydrogenase. Catalysts, 12 (3): (304). [PMID:] [10.3390/catal12030304] |
| 9. Xiaoxiang Hu, Yajun Bai, Tai-Ping Fan, Xiaohui Zheng, Yujie Cai. (2020) A novel type alanine dehydrogenase from Helicobacter aurati: Molecular characterization and application. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 161 (636). [PMID:32534087] [10.1016/j.ijbiomac.2020.06.067] |
| 10. Jie Liu, Yuli Wang, Xiaoxue Liu, Qunhui Yuan, Yang Zhang, Yingchun Li. (2019) Novel molecularly imprinted polymer (MIP) multiple sensors for endogenous redox couples determination and their applications in lung cancer diagnosis. TALANTA, 199 (573). [PMID:30952300] [10.1016/j.talanta.2019.03.018] |
| 11. Kai Tian, Jiang Zhu, Mei Li, Xinghui Qiu. (2019) Capsaicin is efficiently transformed by multiple cytochrome P450s from Capsicum fruit-feeding Helicoverpa armigera. PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 156 (145). [PMID:31027574] [10.1016/j.pestbp.2019.02.015] |
| 12. Lijun Geng, Xudong Yu, Yajuan Li, Yanqiu Wang, Yongquan Wu, Jujie Ren, Fengfeng Xue, Tao Yi. (2019) Instant hydrogel formation of terpyridine-based complexes triggered by DNA via non-covalent interaction. Nanoscale, 11 (9): (4044-4052). [PMID:30768104] [10.1039/C8NR08532C] |
| 13. Huan Zhao, Ying Xu, Shuangjun Lin, Jim C. Spain, Ning-Yi Zhou. (2018) The molecular basis for the intramolecular migration (NIH shift) of the carboxyl group during para-hydroxybenzoate catabolism. MOLECULAR MICROBIOLOGY, 110 (3): (411-424). [PMID:30070064] [10.1111/mmi.14094] |
| 14. Zheng Liandan, Lin Jinping, Zhang Baoqi, Kuang Yuyao, Wei Dongzhi. (2018) Identification of a yeast old yellow enzyme for highly enantioselective reduction of citral isomers to (R)-citronellal. Bioresources and Bioprocessing, 5 (1): (1-12). [PMID:] [10.1186/s40643-018-0192-x] |
| 15. Chen Zhao, Yan Yang, Linfang Wei, Qinghua Guo, Hao Fang, Shaolin Chen, Qiang Hua. (2017) Simultaneous determination of intracellular nucleotides and coenzymes in Yarrowia lipolytica producing lipid and lycopene by capillary zone electrophoresis. JOURNAL OF CHROMATOGRAPHY A, 1514 (120). [PMID:28760603] [10.1016/j.chroma.2017.07.074] |
| 16. Danyu Kang, Ting Geng, Yuanpei Lian, Yanjing Li, Gang Ding, Wenzhe Huang, Shiping Ma, Zhenzhong Wang, Zheng Ma, Wei Xiao. (2017) Direct inhibition of Re Du Ning Injection and its active compounds on human liver cytochrome P450 enzymes by a cocktail method. BIOMEDICAL CHROMATOGRAPHY, 31 (7): (e3905). [PMID:27891633] [10.1002/bmc.3905] |
| 17. Jianyong Li, Xiaojun Kong, Xiwang Li, Yajun Yang, Jiyu Zhang. (2013) Genotoxic evaluation of aspirin eugenol ester using the Ames test and the mouse bone marrow micronucleus assay. FOOD AND CHEMICAL TOXICOLOGY, 62 (805). [PMID:24140966] [10.1016/j.fct.2013.10.010] |
| 18. Rui Cai,Yahong Yuan,Zhouli Wang,Chunfeng Guo,Bin Liu,Laping Liu,Yutang Wang,Tianli Yue. (2015-08-05) Precursors and metabolic pathway for guaiacol production by Alicyclobacillus acidoterrestris.. International journal of food microbiology, 214 (48-53). [PMID:26241489] |
| 19. Kunpeng Li,Rongzhen Zhang,Yan Xu,Zhimeng Wu,Jing Li,Xiaotian Zhou,Jiawei Jiang,Haiyan Liu,Rong Xiao. (2017-06-10) Sortase A-mediated crosslinked short-chain dehydrogenases/reductases as novel biocatalysts with improved thermostability and catalytic efficiency.. Scientific reports, 7 ((1)): (3081-3081). [PMID:28596548] |
| 1. Huang Mingjun, Wu Fanchang, Zuo Xue, Liu Jinman, Yu Wenqian, Xie Ruiye, Liu Guoqing, Tan Qiwen, Wang Qi, Liang Yong. (2023) Quercetin Simultaneously Inhibited Cytochrome P450 and P-Glycoprotein to Improve the Pharmacokinetics of Osthole in Rat Plasma. Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy, (27): (1-10). [PMID:22134922] [10.1007/s43450-023-00487-3] |
| 2. Lai Liang, Zhang Mengyun, Liu Chusheng, Qu Jiahuan, Xu Dongsheng, Jiang Zhengjin. (2023) A comprehensive evaluation of a polymeric zwitterionic hydrophilic monolith for nucleotide separation. ANALYTICAL SCIENCES, (1-7). [PMID:37843729] [10.1007/s44211-023-00430-5] |
| 3. Yan Shi, Wei Xu, Dawei Ni, Wenli Zhang, Cuie Guang, Wanmeng Mu. (2024) Identification and application of a novel deoxynivalenol-degrading enzyme from Youhaiella tibetensis. FOOD CHEMISTRY, 435 (137609). [PMID:37783127] [10.1016/j.foodchem.2023.137609] |
| 4. Jiang Zhu, Ruinan Qu, Yawei Wang, Ruoyao Ni, Kai Tian, Chan Yang, Mei Li, Michael Kristensen, Xinghui Qiu. (2023) Up-regulation of CYP6G4 mediated by a CncC/maf binding-site-containing insertion confers resistance to multiple classes of insecticides in the house fly Musca domestica. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 253 (28): (127024). [PMID:37769776] [10.1016/j.ijbiomac.2023.127024] |
| 5. Nawaz Muhammad, Jiang Yipeng, Xiao Ying, Yu Hao, Wang Zikang, Hu Kun, Zhang Tianao, Hu Jiajun, Gao Min-Tian. (2023) Influence of Different Pretreatment Steps on the Ratio of Phenolic Compounds to Saccharides in Soluble Polysaccharides Derived from Rice Straw and Their Effect on Ethanol Fermentation. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 195 (7): (4552-4569). [PMID:36701092] [10.1007/s12010-023-04337-9] |
| 6. Zhongzhong Lu, Jincong Yan, Mingsheng Xu, Lina Sun, Jihuan Liu, Ye Zhang, Lei Shi, Xifeng Fei, Yi Cao, Renjun Pei. (2023) Hypoxia-Responsive Aggregation of Iron Oxide Nanoparticles for T1-to-T2 Switchable Magnetic Resonance Imaging of Tumors. ACS Applied Nano Materials, 6 (1): (119–130). [PMID:] [10.1021/acsanm.2c03850] |
| 7. Jiang Zhu, Jing Feng, Kai Tian, Chong Li, Mei Li, Xinghui QIU. (2022) Functional characterization of CYP6G4 from the house fly in propoxur metabolism and resistance. PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 187 (105186). [PMID:36127048] [10.1016/j.pestbp.2022.105186] |
| 8. Xinxing Gao, Qianqian Pei, Nianqing Zhu, Yi Mou, Jilei Liang, Xin Zhang, Shoushuai Feng. (2022) Efficient Asymmetric Synthesis of (S)-N-Boc-3-hydroxypiperidine by Coexpressing Ketoreductase and Glucose Dehydrogenase. Catalysts, 12 (3): (304). [PMID:] [10.3390/catal12030304] |
| 9. Xiaoxiang Hu, Yajun Bai, Tai-Ping Fan, Xiaohui Zheng, Yujie Cai. (2020) A novel type alanine dehydrogenase from Helicobacter aurati: Molecular characterization and application. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 161 (636). [PMID:32534087] [10.1016/j.ijbiomac.2020.06.067] |
| 10. Jie Liu, Yuli Wang, Xiaoxue Liu, Qunhui Yuan, Yang Zhang, Yingchun Li. (2019) Novel molecularly imprinted polymer (MIP) multiple sensors for endogenous redox couples determination and their applications in lung cancer diagnosis. TALANTA, 199 (573). [PMID:30952300] [10.1016/j.talanta.2019.03.018] |
| 11. Kai Tian, Jiang Zhu, Mei Li, Xinghui Qiu. (2019) Capsaicin is efficiently transformed by multiple cytochrome P450s from Capsicum fruit-feeding Helicoverpa armigera. PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 156 (145). [PMID:31027574] [10.1016/j.pestbp.2019.02.015] |
| 12. Lijun Geng, Xudong Yu, Yajuan Li, Yanqiu Wang, Yongquan Wu, Jujie Ren, Fengfeng Xue, Tao Yi. (2019) Instant hydrogel formation of terpyridine-based complexes triggered by DNA via non-covalent interaction. Nanoscale, 11 (9): (4044-4052). [PMID:30768104] [10.1039/C8NR08532C] |
| 13. Huan Zhao, Ying Xu, Shuangjun Lin, Jim C. Spain, Ning-Yi Zhou. (2018) The molecular basis for the intramolecular migration (NIH shift) of the carboxyl group during para-hydroxybenzoate catabolism. MOLECULAR MICROBIOLOGY, 110 (3): (411-424). [PMID:30070064] [10.1111/mmi.14094] |
| 14. Zheng Liandan, Lin Jinping, Zhang Baoqi, Kuang Yuyao, Wei Dongzhi. (2018) Identification of a yeast old yellow enzyme for highly enantioselective reduction of citral isomers to (R)-citronellal. Bioresources and Bioprocessing, 5 (1): (1-12). [PMID:] [10.1186/s40643-018-0192-x] |
| 15. Chen Zhao, Yan Yang, Linfang Wei, Qinghua Guo, Hao Fang, Shaolin Chen, Qiang Hua. (2017) Simultaneous determination of intracellular nucleotides and coenzymes in Yarrowia lipolytica producing lipid and lycopene by capillary zone electrophoresis. JOURNAL OF CHROMATOGRAPHY A, 1514 (120). [PMID:28760603] [10.1016/j.chroma.2017.07.074] |
| 16. Danyu Kang, Ting Geng, Yuanpei Lian, Yanjing Li, Gang Ding, Wenzhe Huang, Shiping Ma, Zhenzhong Wang, Zheng Ma, Wei Xiao. (2017) Direct inhibition of Re Du Ning Injection and its active compounds on human liver cytochrome P450 enzymes by a cocktail method. BIOMEDICAL CHROMATOGRAPHY, 31 (7): (e3905). [PMID:27891633] [10.1002/bmc.3905] |
| 17. Jianyong Li, Xiaojun Kong, Xiwang Li, Yajun Yang, Jiyu Zhang. (2013) Genotoxic evaluation of aspirin eugenol ester using the Ames test and the mouse bone marrow micronucleus assay. FOOD AND CHEMICAL TOXICOLOGY, 62 (805). [PMID:24140966] [10.1016/j.fct.2013.10.010] |
| 18. Rui Cai,Yahong Yuan,Zhouli Wang,Chunfeng Guo,Bin Liu,Laping Liu,Yutang Wang,Tianli Yue. (2015-08-05) Precursors and metabolic pathway for guaiacol production by Alicyclobacillus acidoterrestris.. International journal of food microbiology, 214 (48-53). [PMID:26241489] |
| 19. Kunpeng Li,Rongzhen Zhang,Yan Xu,Zhimeng Wu,Jing Li,Xiaotian Zhou,Jiawei Jiang,Haiyan Liu,Rong Xiao. (2017-06-10) Sortase A-mediated crosslinked short-chain dehydrogenases/reductases as novel biocatalysts with improved thermostability and catalytic efficiency.. Scientific reports, 7 ((1)): (3081-3081). [PMID:28596548] |
