atuzabrutinib - ≥98%, high purity , CAS No.1581714-49-9, Inhibitor of Bruton tyrosine kinase

Item Number

A607809

Grouped product items
SKU	Size	Availability	Price
A607809-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$179.90
A607809-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$454.90
A607809-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$753.90
A607809-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,489.90

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Basic Description

Synonyms	PRN473 \| SAR444727
Specifications & Purity	Moligand™, ≥98%
Storage Temp	Protected from light,Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of Bruton tyrosine kinase
Product Description	Atuzabrutinib (SAR 444727) is a potent, selective reversible inhibitor of Btk (Bruton's tyrosine kinase) inhibitor. Atuzabrutinib inhibits neutrophil recruitment via inhibition of macrophage antigen-1 signalling.

Names and Identifiers

IUPAC Name	(E)-2-[(3R)-3-[4-amino-3-(2-fluoro-4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4,4-dimethylpent-2-enenitrile
INCHI	InChI=1S/C30H30FN7O2/c1-30(2,3)15-19(16-32)29(39)37-13-7-8-20(17-37)38-28-25(27(33)34-18-35-28)26(36-38)23-12-11-22(14-24(23)31)40-21-9-5-4-6-10-21/h4-6,9-12,14-15,18,20H,7-8,13,17H2,1-3H3,(H2,33,34,35)/b19-15+/t20-/m1/s1
InChi Key	KZMQPYCXSAGLTB-ZWUNQBBJSA-N
Canonical SMILES	Nc1c2c(ncn1)n(nc2c1c(cc(cc1)Oc1ccccc1)F)[C@H]1CN(CCC1)C(=O)/C(=C/C(C)(C)C)/C#N
Isomeric SMILES	CC(C)(C)/C=C(\C#N)/C(=O)N1CCC[C@H](C1)N2C3=NC=NC(=C3C(=N2)C4=C(C=C(C=C4)OC5=CC=CC=C5)F)N
PubChem CID	73438222
Molecular Weight	539.60

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

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8 results found

Lot Number	Certificate Type	Date	Item
C2512320	Certificate of Analysis	Oct 18, 2024	A607809
C2512334	Certificate of Analysis	Oct 18, 2024	A607809
C2512335	Certificate of Analysis	Oct 18, 2024	A607809
C2512336	Certificate of Analysis	Oct 18, 2024	A607809
C2512337	Certificate of Analysis	Oct 18, 2024	A607809
C2512338	Certificate of Analysis	Oct 18, 2024	A607809
C2512339	Certificate of Analysis	Oct 18, 2024	A607809
C2512340	Certificate of Analysis	Oct 18, 2024	A607809

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Basic Description