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ATP-gamma-S - ≥80%, high purity , CAS No.93839-89-5

  • ≥80%
Item Number
A274887
Grouped product items
SKUSizeAvailabilityPrice Qty
A274887-1mg
1mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$89.90
A274887-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$400.90
A274887-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$759.90
A274887-25mg
25mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$1,802.90
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Kinase substrate

View related series
Cell Cycle/DNA Damage (0) Enzyme inhibitors and enzyme substrates (0) Eukaryotic Initiation Factor (eIF) (0) Nucleotides/Nucleosides (0)

Basic Description

SynonymsAdenosine 5'-(γ-thio)-triphosphate (lithium salt) | P'-anhydride with phosphorothioic acid adenosine 5'-(trihydrogen diphosphate), tetralithium salt | Adenosine 5′-[γ-thio]triphosphate tetralithium salt | ATP-γ-S | Ado-5′-PPP[S]
Specifications & Purity≥80%
Biochemical and Physiological MechanismsAdenosine 5′-[γ-thio]triphosphate (ATP-γ-S) is widely used as a non-hydrolyzed ATP analogue for studies on the effects of ATP binding to ATP sites in a wide range of processes including extracellular functions. ATP- γ-S is a P2 purinergic agonist which in
Storage TempStore at -20°C,Desiccated
Shipped InIce chest + Ice pads
NoteThis product is supplied in one (or more) pack size which is freeze dried. Therefore the contents may not be readily visible, as they can coat the bottom or walls of the vial. Please see our FAQs and information page for more details on handling. Unstable; make up solutions fresh and use immediately. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Adenosine 5′-[γ-thio]triphosphate tetralithium salt has been used to treat the pollen grains to determine the inhibitory effect of adenosine triphosphate (ATP) or its hydrolysis product. It has also been used to select thiophosphorylate target protein.

AI Insight

Names and Identifiers

IUPAC Name tetralithium;[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] dioxidophosphinothioyl phosphate
INCHI InChI=1S/C10H16N5O12P3S.4Li/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(25-10)1-24-28(18,19)26-29(20,21)27-30(22,23)31;;;;/h2-4,6-7,10,16-17H,1H2,(H,18,19)(H,20,21)(H2,11,12,13)(H2,22,23,31);;;;/q;4*+1/p-4/t4-,6-,7-,10-;;;;/m1..../s1
InChi Key DWQFDOIBOYDYKH-KWIZKVQNSA-J
Canonical SMILES [Li+].[Li+].[Li+].[Li+].C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)([O-])OP(=O)([O-])OP(=S)([O-])[O-])O)O)N
Isomeric SMILES [Li+].[Li+].[Li+].[Li+].C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)([O-])OP(=O)([O-])OP(=S)([O-])[O-])O)O)N
Alternate CAS 35094-45-2（free）
Molecular Weight 546.98

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

21 results found

Lot NumberCertificate TypeDateItem
E2422524Certificate of AnalysisMar 04, 2025 A274887
E2422489Certificate of AnalysisMar 04, 2025 A274887
C2414018Certificate of AnalysisDec 13, 2024 A274887
K2419251Certificate of AnalysisNov 06, 2024 A274887
K2419199Certificate of AnalysisNov 06, 2024 A274887
K2419198Certificate of AnalysisNov 06, 2024 A274887
K2419197Certificate of AnalysisNov 06, 2024 A274887
A2409015Certificate of AnalysisOct 18, 2024 A274887
J2325105Certificate of AnalysisAug 19, 2024 A274887
J2325103Certificate of AnalysisOct 17, 2023 A274887
J2325104Certificate of AnalysisOct 17, 2023 A274887
H2302171Certificate of AnalysisJul 15, 2023 A274887
H2302181Certificate of AnalysisJul 15, 2023 A274887
E2317297Certificate of AnalysisMay 12, 2023 A274887
E2317289Certificate of AnalysisMay 12, 2023 A274887
D2321009Certificate of AnalysisApr 14, 2023 A274887
D2321006Certificate of AnalysisApr 14, 2023 A274887
J2229049Certificate of AnalysisOct 11, 2022 A274887
J2229050Certificate of AnalysisOct 11, 2022 A274887
G2205059Certificate of AnalysisJun 20, 2022 A274887
G2205060Certificate of AnalysisJun 20, 2022 A274887

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Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

Related Documents

 SDS

 Specification Sheet

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Reviews

Customer Reviews

References

1. Allen JJ et al..  (2007)  A semisynthetic epitope for kinase substrates..  Nat Methods,  4  (6): (511-6).  [PMID:17486086]
2. Zhang H et al..  (2021)  A subcellular map of the human kinome..  Elife,  10    [PMID:33988507]
3. Guo J et al..  (2019)  AKT methylation by SETDB1 promotes AKT kinase activity and oncogenic functions..  Nat Cell Biol,  21  (2): (226-237).  [PMID:30692625]
4. Ryzhakov G et al..  (2021)  Defactinib inhibits PYK2 phosphorylation of IRF5 and reduces intestinal inflammation..  Nat Commun,  12  (6702).  [PMID:34795257]
5. Dai X et al..  (2021)  Energy status dictates PD-L1 protein abundance and anti-tumor immunity to enable checkpoint blockade..  Mol Cell,  81  (11): (2317-2331.e6).  [PMID:33909988]
6. Yildirim AD et al..  (2022)  ER Stress-Induced Sphingosine-1-Phosphate Lyase Phosphorylation Potentiates the Mitochondrial Unfolded Protein Response..  J Lipid Res,  63  (10): (100279).  [PMID:36100091]
7. Ohta M et al..  (2018)  IL-1ß and TNF-a suppress TGF-ß-promoted NGF expression in periodontal ligament-derived fibroblasts through inactivation of TGF-ß-induced Smad2/3- and p38 MAPK-mediated signals..  Int J Mol Med,  42  (3): (1484-1494).  [PMID:29901090]
8. Lertsuwan J & Ruchirawat M.  (2017)  Inhibitory Effects of ATP and Adenosine on Cholangiocarcinoma Cell Proliferation and Motility..  Anticancer Res,  37  (7): (3553-3561).  [PMID:28668846]
9. Yildirim Z et al..  (2022)  Intercepting IRE1 kinase-FMRP signaling prevents atherosclerosis progression..  EMBO Mol Med,  14  (4): (e15344).  [PMID:35191199]
10. Liu S et al..  (2017)  Lck/Hck/Fgr-Mediated Tyrosine Phosphorylation Negatively Regulates TBK1 to Restrain Innate Antiviral Responses..  Cell Host Microbe,  21  (6): (754-768.e5).  [PMID:28618271]
11. An L et al..  (2020)  MST4 kinase suppresses gastric tumorigenesis by limiting YAP activation via a non-canonical pathway..  J Exp Med,  217  (6):   [PMID:32271880]
12. Zhang G et al..  (2018)  mTOR Regulates Phase Separation of PGL Granules to Modulate Their Autophagic Degradation..  Cell,  174  (6): (1492-1506.e22).  [PMID:30173914]
13. Jin X et al..  (2019)  PES1 promotes BET inhibitors resistance and cells proliferation through increasing c-Myc expression in pancreatic cancer..  J Exp Clin Cancer Res,  38  (463).  [PMID:31718704]
14. Lo CH et al..  (2019)  Phosphorylation of CEP83 by TTBK2 is necessary for cilia initiation..  J Cell Biol,  218  (10): (3489-3505).  [PMID:31455668]
15. Han H et al..  (2020)  PINK1 phosphorylates Drp1S616 to regulate mitophagy-independent mitochondrial dynamics..  EMBO Rep,  21  (8): (e48686).  [PMID:32484300]
16. Terse A et al..  (2021)  Protocols for Characterization of Cdk5 Kinase Activity..  Curr Protoc,  1  (10): (e276).  [PMID:34679246]
17. Yu CC et al..  (2022)  Sequential Phosphorylation of Hepatitis C Virus NS5A Protein Requires the ATP-Binding Domain of NS3 Helicase..  J Virol,  96  (7): (e0010722).  [PMID:35293767]
18. Zhong J et al..  (2022)  Structural basis of dynamic P5CS filaments..  Elife,  11    [PMID:35286254]
19. Yu B et al..  (2021)  SUMO proteases SENP3 and SENP5 spatiotemporally regulate the kinase activity of Aurora A..  J Cell Sci,  134  (13):   [PMID:34313310]
20. Chen Y et al..  (2020)  Systematic analysis of the Hippo pathway organization and oncogenic alteration in evolution..  Sci Rep,  10  (3173).  [PMID:32081887]
21. Han H et al..  (2022)  The Hippo pathway kinases LATS1 and LATS2 attenuate cellular responses to heavy metals through phosphorylating MTF1..  Nat Cell Biol,  24  (74-87).  [PMID:35027733]
22. Lee PC & Machner MP.  (2018)  The Legionella Effector Kinase LegK7 Hijacks the Host Hippo Pathway to Promote Infection..  Cell Host Microbe,  24  (3): (429-438.e6).  [PMID:30212651]

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