| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| A287232-5mg | 5mg | 3 | $88.90 | |
| A287232-10mg | 10mg | 3 | $147.90 | |
| A287232-25mg | 25mg | 3 | $325.90 | |
| A287232-50mg | 50mg | 3 | $523.90 | |
| A287232-100mg | 100mg | 2 | $840.90 | |
| A287232-250mg | 250mg | 2 | $1,892.90 |
FFA3 agonist
| Synonyms | N-(2,5-Dichlorophenyl)-4-(furan-2-yl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxamide | AR420626 |
|---|---|
| Specifications & Purity | ≥98%(HPLC) |
| Biochemical and Physiological Mechanisms | FFA3 agonist (pEC50= 5.74). Inhibits nicotine and serotonin induced changes in motility of isolated muscle strips from rat colon. Also suppresses serotonin-induced fecal output in rats. |
| Storage Temp | Store at -20°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | product description： AR420626 is a selective agonist of free fatty acid receptor 3 (FFAR3, GPR41) with IC50 of 117 nM. AR420626 inhibits nicotine and serotonin-induced changes in motility of isolated muscle strips from rat colon and suppresses serotonin-induced fecal output in rats。 |
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| Pubchem Sid | 504772689 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504772689 |
| IUPAC Name | N-(2,5-dichlorophenyl)-4-(furan-2-yl)-2-methyl-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxamide |
| INCHI | InChI=1S/C21H18Cl2N2O3/c1-11-18(21(27)25-15-10-12(22)7-8-13(15)23)20(17-6-3-9-28-17)19-14(24-11)4-2-5-16(19)26/h3,6-10,20,24H,2,4-5H2,1H3,(H,25,27) |
| InChi Key | GGTYQECCGLBHGS-UHFFFAOYSA-N |
| Canonical SMILES | CC1=C(C(C2=C(N1)CCCC2=O)C3=CC=CO3)C(=O)NC4=C(C=CC(=C4)Cl)Cl |
| Isomeric SMILES | CC1=C(C(C2=C(N1)CCCC2=O)C3=CC=CO3)C(=O)NC4=C(C=CC(=C4)Cl)Cl |
| PubChem CID | 91885415 |
| Molecular Weight | 417.29 |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 H2218183 | Certificate of Analysis | Jun 02, 2022 | A287232 |
| H2218184 | Certificate of Analysis | Jun 02, 2022 | A287232 |
| H2218185 | Certificate of Analysis | Jun 02, 2022 | A287232 |
| H2218186 | Certificate of Analysis | Jun 02, 2022 | A287232 |
| H2218188 | Certificate of Analysis | Jun 02, 2022 | A287232 |
| H2218190 | Certificate of Analysis | Jun 02, 2022 | A287232 |
