| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| A286711-1mg | 1mg | 4 | $79.90 | |
| A286711-5mg | 5mg | 3 | $279.90 | |
| A286711-10mg | 10mg | 2 | $513.90 |
Kir6 blocker; non-hydrolyzable AMP analog
| Synonyms | AMP PNP | PD080102 | tetralithium;[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-(phosphonatoamino)phosphinate | AMP-PNP (tetralithium) | Adenylyl-imidodiphosphate,tetralithium salt | EINECS 277-127-5 | Adenosin |
|---|---|
| Specifications & Purity | ≥90%(HPLC) |
| Biochemical and Physiological Mechanisms | Non-hydrolyzable AMP analog. Kir6 (KATP) channel blocker. Inhibits fast axonal transport and stabilizes the interaction of membranous organelles with microtubules. |
| Storage Temp | Store at -20°C |
| Shipped In | Ice chest + Ice pads |
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| Pubchem Sid | 504765312 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504765312 |
| IUPAC Name | tetralithium;[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-(phosphonatoamino)phosphinate |
| INCHI | InChI=1S/C10H17N6O12P3.4Li/c11-8-5-9(13-2-12-8)16(3-14-5)10-7(18)6(17)4(27-10)1-26-31(24,25)28-30(22,23)15-29(19,20)21;;;;/h2-4,6-7,10,17-18H,1H2,(H,24,25)(H2,11,12,13)(H4,15,19,20,21,22,23);;;;/q;4*+1/p-4/t4-,6-,7-,10-;;;;/m1..../s1 |
| InChi Key | FDBDJIGGLGUOPP-KWIZKVQNSA-J |
| Canonical SMILES | [Li+].[Li+].[Li+].[Li+].C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)([O-])OP(=O)(NP(=O)([O-])[O-])[O-])O)O)N |
| Isomeric SMILES | [Li+].[Li+].[Li+].[Li+].C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)([O-])OP(=O)(NP(=O)([O-])[O-])[O-])O)O)N |
| Alternate CAS | 25612-73-1； |
| PubChem CID | 10196276 |
| Molecular Weight | 506.20 (free acid basis) |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 J2326021 | Certificate of Analysis | Oct 07, 2023 | A286711 |
| J2326024 | Certificate of Analysis | Oct 07, 2023 | A286711 |
| J2326025 | Certificate of Analysis | Oct 07, 2023 | A286711 |
| L2426130 | Certificate of Analysis | Oct 07, 2023 | A286711 |
| E23301001 | Certificate of Analysis | May 18, 2023 | A286711 |
| E23301004 | Certificate of Analysis | May 18, 2023 | A286711 |
| E2330987 | Certificate of Analysis | May 18, 2023 | A286711 |
| E2330990 | Certificate of Analysis | May 18, 2023 | A286711 |
| E2330998 | Certificate of Analysis | May 18, 2023 | A286711 |
| E2330999 | Certificate of Analysis | May 18, 2023 | A286711 |
| J2209077 | Certificate of Analysis | Aug 03, 2022 | A286711 |
| J2209111 | Certificate of Analysis | Aug 03, 2022 | A286711 |
| J2209112 | Certificate of Analysis | Aug 03, 2022 | A286711 |
