| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| A425434-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $69.90 |
Selective TBK1 and IKKε inhibitor
| Synonyms | amlexanox | 68302-57-8 | Amoxanox | Aphthasol | 2-Amino-7-isopropyl-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid | Amlenanox | Elics | AA-673 | Amlexanoxo | Amlexanoxum | Amlexanoxum [Latin] | Amlexanoxo [Spanish] | CHX 3673 | aphtheal | CHX-3673 | AA 673 | 2-amino-5-oxo-7-(propan |
|---|---|
| Specifications & Purity | Moligand™, 10mM in DMSO |
| Biochemical and Physiological Mechanisms | Selective TBK1 and IKKε inhibitor (IC 50 = 1-2 μM). Shows antiallergic, antiobesogenic and anti-inflammatory effects in vivo. Orally active. |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Grade | Moligand™ |
| Action Type | INHIBITOR |
| Mechanism of action | Phosphodiesterase 4 inhibitor |
| ALogP | 3.1 |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| IUPAC Name | 2-amino-5-oxo-7-propan-2-ylchromeno[2,3-b]pyridine-3-carboxylic acid |
|---|---|
| INCHI | InChI=1S/C16H14N2O4/c1-7(2)8-3-4-12-9(5-8)13(19)10-6-11(16(20)21)14(17)18-15(10)22-12/h3-7H,1-2H3,(H2,17,18)(H,20,21) |
| InChi Key | SGRYPYWGNKJSDL-UHFFFAOYSA-N |
| Canonical SMILES | CC(C)C1=CC2=C(C=C1)OC3=NC(=C(C=C3C2=O)C(=O)O)N |
| Isomeric SMILES | CC(C)C1=CC2=C(C=C1)OC3=NC(=C(C=C3C2=O)C(=O)O)N |
| WGK Germany | 3 |
| PubChem CID | 2161 |
| Molecular Weight | 298.29 |
| Pictogram(s) | GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H302:Harmful if swallowed |
| Precautionary Statements | P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help. |
| WGK Germany | 3 |
| Merck Index | 490 |
