Aluminum Ionophore I - >90.0%(HPLC), high purity , CAS No.480-16-0, Antagonist of A 1 receptor;Antagonist of A 2A receptor

Item Number
A135920
Grouped product items
SKUSizeAvailabilityPrice Qty
A135920-100mg
100mg
2
$42.90
A135920-250mg
250mg
1
$79.90
A135920-1g
1g
1
$220.90
A135920-5g
5g
1
$728.90

Basic Description

SynonymsFlavone,3,4',5,7-pentahydroxy- | KBio1_000958 | s10675 | cid_5281670 | NCGC00015672-09 | 2',4',5, 7-Tetrahydroxyflavan-3-ol | 8NFQ3F76WR | AI3-38057 | C.I. 75660 | CHEBI:75092 | Spectrum2_000715 | 2',3,5,7-Pentahydroxyflavone | 3,5,7,2',4'-Pentahydroxyfla
Specifications & PurityMoligand™, ≥90%(HPLC)
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeANTAGONIST
Mechanism of actionAntagonist of A 1 receptor;Antagonist of A 2A receptor
Product Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. 


AI Insight

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid504763373
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504763373
IUPAC Name 2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one
INCHI InChI=1S/C15H10O7/c16-6-1-2-8(9(18)3-6)15-14(21)13(20)12-10(19)4-7(17)5-11(12)22-15/h1-5,16-19,21H
InChi Key YXOLAZRVSSWPPT-UHFFFAOYSA-N
Canonical SMILES C1=CC(=C(C=C1O)O)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O
Isomeric SMILES C1=CC(=C(C=C1O)O)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O
PubChem CID 5281670
Molecular Weight 302.24

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot NumberCertificate TypeDateItem
I2223417Certificate of AnalysisJul 19, 2024 A135920
I2223418Certificate of AnalysisJul 19, 2024 A135920
I2223419Certificate of AnalysisJul 19, 2024 A135920
I2223420Certificate of AnalysisJul 19, 2024 A135920

Safety and Hazards(GHS)

Pictogram(s) GHS06,   GHS08,   GHS09,   GHS07
Signal Danger
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H301:Toxic if swallowed

H341:Suspected of causing genetic defects

H411:Toxic to aquatic life with long lasting effects

H302:Harmful if swallowed

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P273:Avoid release to the environment.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P281:Use personal protective equipment as required.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P391:Collect spillage.

P330:Rinse mouth.

P203:Obtain, read and follow all safety instructions before use.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P316:IF SWALLOWED: Get emergency medical help immediately.

P301+P317:IF SWALLOWED: Get medical help.

P318:if exposed or concerned, get medical advice.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

Related Documents

Reviews

Customer Reviews

Citations of This Product

1. Tian Yang, Zhong Zhang, Fangjian Ning, Li Yuan, Xingbin Yang, Liping Luo.  (2024)  New theoretical perspective for easy evaluation of the antioxidant properties of typical flavonoids.  MICROCHEMICAL JOURNAL,  197  (109786).  [PMID:] [10.1016/j.microc.2023.109786]
2. Qing Li, Run Lu, Huiyu Jiang, Yuyang Zhou.  (2023)  Efficient and sustainable bleaching of cotton/spandex integrating UVA radiation and peroxide activator: A study focus on the degradation mechanism of natural pigments in fibres.  Arabian Journal of Chemistry,  16  (29): (105348).  [PMID:11006272] [10.1016/j.arabjc.2023.105348]
3. Xiaodan Tang, Yichao Zhao, Hongmei Yu, Shuanping Cui, Hunter Temple, Eric Amador, Yun Gao, Ming-li Chen, Shaoyan Wang, Zhizhi Hu, Wei Chen.  (2023)  Concentration-regulated multi-color fluorescent carbon dots for the detection of rifampicin, morin and Al3+.  Materials Today Advances,  18  (100383).  [PMID:] [10.1016/j.mtadv.2023.100383]
4. Heng Ye, Gang Wang, Xuchao Wang, Lin Wang, Wei Ni, Linjian Chen, Yifan Zhu, Longshan Zhao, Zhili Xiong, Yan Wang, Cuilian Dai, Binbin Liu.  (2023)  San-wei-tan-xiang capsule attenuates atherosclerosis by increasing lysosomal activity in adipose tissue macrophages.  JOURNAL OF ETHNOPHARMACOLOGY,  312  (116444).  [PMID:37061068] [10.1016/j.jep.2023.116444]
5. Rongqian Meng, Yanfeng Xue, Lijun Guo, Hong Yang, Yongbo Song, Qiaoling Li, Yulan Niu.  (2022)  Overoxidized polypyrrole/overoxidized poly(3,4-ethylenedioxythiophene)/graphene quantum dots-chitosan as enhanced electrochemical sensing platform for luteolin determination in peanut shells.  NEW JOURNAL OF CHEMISTRY,  46  (43): (20610-20622).  [PMID:] [10.1039/D2NJ03738F]
6. Qing Li, Run Lu, Yan Liang, Kang Gao, Huiyu Jiang.  (2022)  Energy-Saving One-Step Pre-Treatment Using an Activated Sodium Percarbonate System and Its Bleaching Mechanism for Cotton Fabric.  Materials,  15  (17): (5849).  [PMID:36079230] [10.3390/ma15175849]
7. Yumin Hao, Wenjuan Dong, Yang Liu, Xiaole Wen, Shaomin Shuang, Qin Hu, Chuan Dong, Xiaojuan Gong.  (2022)  Nitrogen-doped carbon dots coupled with morin-Al3+: Cleverly design an integrated sensing platform for ratiometric optical dual-mode and smartphone-assisted visual detection of fluoride ion.  JOURNAL OF HAZARDOUS MATERIALS,  439  (129596).  [PMID:35863221] [10.1016/j.jhazmat.2022.129596]
8. Siyuan Tang, Xiameng Li, Changxing Wang, Tingting Li, Guoqiang Guo, Yiru Wang, Da Chen.  (2022)  Target-oriented synthesis of high synthetic yield carbon dots by waxberry for optical dual-mode and smartphone imaging detection of morin.  MATERIALS LETTERS,  324  (132673).  [PMID:] [10.1016/j.matlet.2022.132673]
9. Rongqian Meng, Jianke Tang, Xiaojun Wu, Shengjian Zhang, Xin Wang, Qiaoling Li, Riya Jin.  (2021)  Molecularly Imprinted Electrochemical Sensor Based on 3D Wormlike PEDOT-PPy Polymer for the Sensitive Determination of Rutin in Flos Sophorae Immaturus.  JOURNAL OF THE ELECTROCHEMICAL SOCIETY,  168  (7): (77521).  [PMID:] [10.1149/1945-7111/ac0f8a]
10. Guangqian Yang, Zhengyi Liu, Tingting Lan, Li Dou, Kankan Zhang.  (2021)  Potential enantioselectivity of the hydrolysation and photolysation of the chiral agrochemical penthiopyrad in aquatic environments.  Environmental Science-Water Research & Technology,  (7): (1220-1229).  [PMID:] [10.1039/D1EW00098E]
11. Yanan Yan, Lin Li, Huilin Zhang, Fangfang Du, Yating Meng, Shaomin Shuang, Ruibing Wang, Shengmei Song, Chuan Dong.  (2021)  Carbon dots for ratiometric fluorescence detection of morin.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  256  (119751).  [PMID:33819765] [10.1016/j.saa.2021.119751]
12. Xueqing Guo, Yang Liu, Wenjuan Dong, Qin Hu, Yong Li, Shaomin Shuang, Chuan Dong, Lishuai Cai, Xiaojuan Gong.  (2021)  Azithromycin detection in cells and tablets by N,S co-doped carbon quantum dots.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  252  (119506).  [PMID:33561684] [10.1016/j.saa.2021.119506]
13. Zhixia Yao, Hanmeng Liu, Yaosheng Liu, Yongxing Diao, Guangxing Hu, Qifang Zhang, Zhuang Li.  (2021)  FRET-based fluorometry assay for curcumin detecting using PVP-templated Cu NCs.  TALANTA,  223  (121741).  [PMID:33298267] [10.1016/j.talanta.2020.121741]
14. Shuqian Yu, Yanshuai Cui, Xiaolei Guo, Shengfu Chen, Haotian Sun, Longgang Wang, Jing Wang, Yu Zhao, Zhiwei Liu.  (2019)  Biocompatible bovine serum albumin stabilized platinum nanoparticles for the oxidation of morin.  NEW JOURNAL OF CHEMISTRY,  43  (22): (8774-8780).  [PMID:] [10.1039/C9NJ00887J]
15. Meihui Fan, Huafang Ding, Guowen Zhang, Xing Hu, Deming Gong.  (2019)  Relationships of dietary flavonoid structure with its tyrosinase inhibitory activity and affinity.  LWT-FOOD SCIENCE AND TECHNOLOGY,  107  (25).  [PMID:] [10.1016/j.lwt.2019.02.076]
16. Longgang Wang, Jin Zhang, Xiaolei Guo, Shengfu Chen, Yanshuai Cui, Qingyu Yu, Lubin Yang, Haotian Sun, Dawei Gao, Danyang Xie.  (2018)  Highly stable and biocompatible zwitterionic dendrimer-encapsulated palladium nanoparticles that maintain their catalytic activity in bacterial solution.  NEW JOURNAL OF CHEMISTRY,  42  (24): (19740-19748).  [PMID:] [10.1039/C8NJ04263B]
17. Wang Qianqian, Xu Yixiang, Xu Jiaqi, Wang Xudong, Shen Chen, Zhang Yan, Liu Xiufeng, Yu Boyang, Zhang Jian.  (2017)  Molecular cloning and expression of a glycosyltransferase from Bacillus subtilis for modification of morin and related polyphenols.  BIOTECHNOLOGY LETTERS,  39  (8): (1229-1235).  [PMID:28484911] [10.1007/s10529-017-2352-z]
18. Yang Huang, Ying Feng, Guangyun Tang, Minyi Li, Tingting Zhang, Marianne Fillet, Jacques Crommen, Zhengjin Jiang.  (2017)  Development and validation of a fast SFC method for the analysis of flavonoids in plant extracts.  JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,  140  (384).  [PMID:28347593] [10.1016/j.jpba.2017.03.012]
19. Shuzhen Yang, Jie Zhou, Dongmei Li, Chunyu Shang, Litao Peng, Siyi Pan.  (2017)  The structure-antifungal activity relationship of 5,7-dihydroxyflavonoids against Penicillium italicum.  FOOD CHEMISTRY,  224  (26).  [PMID:28159264] [10.1016/j.foodchem.2016.12.001]
20. Depeng Kong, Fanyong Yan, Yunmei Luo, Qianghua Ye, Siyushan Zhou, Li Chen.  (2017)  Amphiphilic carbon dots for sensitive detection, intracellular imaging of Al3+.  ANALYTICA CHIMICA ACTA,  953  (63).  [PMID:28010744] [10.1016/j.aca.2016.11.049]
21. Li Zeng, Guowen Zhang, Yijing Liao, Deming Gong.  (2016)  Inhibitory mechanism of morin on α-glucosidase and its anti-glycation properties.  Food & Function,  (9): (3953-3963).  [PMID:27549567] [10.1039/C6FO00680A]
22. Suyun Lin, Guowen Zhang, Yijing Liao, Junhui Pan, Deming Gong.  (2015)  Dietary Flavonoids as Xanthine Oxidase Inhibitors: Structure–Affinity and Structure–Activity Relationships.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,  63  (35): (7784–7794).  [PMID:26285120] [10.1021/acs.jafc.5b03386]
23. Xiaodan Liu, Xia Wu.  (2014)  Fluorescence enhancement of fisetin by silver nanoparticles with cetyltrimethyl ammonium bromide micelles.  RSC Advances,  (10): (7433-7439).  [PMID:] [10.1039/C4RA12726A]
24. Bowen Xiao, Huijuan Wang, Xijuan Zhao, Yuanfang Li.  (2014)  Selective recognition of luteolin and quercetin based on the specific interaction of ortho-dihydroxy substituents with a zinc(II) complex.  Analytical Methods,  (9): (2894-2899).  [PMID:] [10.1039/C4AY00066H]

References

1. Tian Yang, Zhong Zhang, Fangjian Ning, Li Yuan, Xingbin Yang, Liping Luo.  (2024)  New theoretical perspective for easy evaluation of the antioxidant properties of typical flavonoids.  MICROCHEMICAL JOURNAL,  197  (109786).  [PMID:] [10.1016/j.microc.2023.109786]
2. Qing Li, Run Lu, Huiyu Jiang, Yuyang Zhou.  (2023)  Efficient and sustainable bleaching of cotton/spandex integrating UVA radiation and peroxide activator: A study focus on the degradation mechanism of natural pigments in fibres.  Arabian Journal of Chemistry,  16  (29): (105348).  [PMID:11006272] [10.1016/j.arabjc.2023.105348]
3. Xiaodan Tang, Yichao Zhao, Hongmei Yu, Shuanping Cui, Hunter Temple, Eric Amador, Yun Gao, Ming-li Chen, Shaoyan Wang, Zhizhi Hu, Wei Chen.  (2023)  Concentration-regulated multi-color fluorescent carbon dots for the detection of rifampicin, morin and Al3+.  Materials Today Advances,  18  (100383).  [PMID:] [10.1016/j.mtadv.2023.100383]
4. Heng Ye, Gang Wang, Xuchao Wang, Lin Wang, Wei Ni, Linjian Chen, Yifan Zhu, Longshan Zhao, Zhili Xiong, Yan Wang, Cuilian Dai, Binbin Liu.  (2023)  San-wei-tan-xiang capsule attenuates atherosclerosis by increasing lysosomal activity in adipose tissue macrophages.  JOURNAL OF ETHNOPHARMACOLOGY,  312  (116444).  [PMID:37061068] [10.1016/j.jep.2023.116444]
5. Rongqian Meng, Yanfeng Xue, Lijun Guo, Hong Yang, Yongbo Song, Qiaoling Li, Yulan Niu.  (2022)  Overoxidized polypyrrole/overoxidized poly(3,4-ethylenedioxythiophene)/graphene quantum dots-chitosan as enhanced electrochemical sensing platform for luteolin determination in peanut shells.  NEW JOURNAL OF CHEMISTRY,  46  (43): (20610-20622).  [PMID:] [10.1039/D2NJ03738F]
6. Qing Li, Run Lu, Yan Liang, Kang Gao, Huiyu Jiang.  (2022)  Energy-Saving One-Step Pre-Treatment Using an Activated Sodium Percarbonate System and Its Bleaching Mechanism for Cotton Fabric.  Materials,  15  (17): (5849).  [PMID:36079230] [10.3390/ma15175849]
7. Yumin Hao, Wenjuan Dong, Yang Liu, Xiaole Wen, Shaomin Shuang, Qin Hu, Chuan Dong, Xiaojuan Gong.  (2022)  Nitrogen-doped carbon dots coupled with morin-Al3+: Cleverly design an integrated sensing platform for ratiometric optical dual-mode and smartphone-assisted visual detection of fluoride ion.  JOURNAL OF HAZARDOUS MATERIALS,  439  (129596).  [PMID:35863221] [10.1016/j.jhazmat.2022.129596]
8. Siyuan Tang, Xiameng Li, Changxing Wang, Tingting Li, Guoqiang Guo, Yiru Wang, Da Chen.  (2022)  Target-oriented synthesis of high synthetic yield carbon dots by waxberry for optical dual-mode and smartphone imaging detection of morin.  MATERIALS LETTERS,  324  (132673).  [PMID:] [10.1016/j.matlet.2022.132673]
9. Rongqian Meng, Jianke Tang, Xiaojun Wu, Shengjian Zhang, Xin Wang, Qiaoling Li, Riya Jin.  (2021)  Molecularly Imprinted Electrochemical Sensor Based on 3D Wormlike PEDOT-PPy Polymer for the Sensitive Determination of Rutin in Flos Sophorae Immaturus.  JOURNAL OF THE ELECTROCHEMICAL SOCIETY,  168  (7): (77521).  [PMID:] [10.1149/1945-7111/ac0f8a]
10. Guangqian Yang, Zhengyi Liu, Tingting Lan, Li Dou, Kankan Zhang.  (2021)  Potential enantioselectivity of the hydrolysation and photolysation of the chiral agrochemical penthiopyrad in aquatic environments.  Environmental Science-Water Research & Technology,  (7): (1220-1229).  [PMID:] [10.1039/D1EW00098E]
11. Yanan Yan, Lin Li, Huilin Zhang, Fangfang Du, Yating Meng, Shaomin Shuang, Ruibing Wang, Shengmei Song, Chuan Dong.  (2021)  Carbon dots for ratiometric fluorescence detection of morin.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  256  (119751).  [PMID:33819765] [10.1016/j.saa.2021.119751]
12. Xueqing Guo, Yang Liu, Wenjuan Dong, Qin Hu, Yong Li, Shaomin Shuang, Chuan Dong, Lishuai Cai, Xiaojuan Gong.  (2021)  Azithromycin detection in cells and tablets by N,S co-doped carbon quantum dots.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  252  (119506).  [PMID:33561684] [10.1016/j.saa.2021.119506]
13. Zhixia Yao, Hanmeng Liu, Yaosheng Liu, Yongxing Diao, Guangxing Hu, Qifang Zhang, Zhuang Li.  (2021)  FRET-based fluorometry assay for curcumin detecting using PVP-templated Cu NCs.  TALANTA,  223  (121741).  [PMID:33298267] [10.1016/j.talanta.2020.121741]
14. Shuqian Yu, Yanshuai Cui, Xiaolei Guo, Shengfu Chen, Haotian Sun, Longgang Wang, Jing Wang, Yu Zhao, Zhiwei Liu.  (2019)  Biocompatible bovine serum albumin stabilized platinum nanoparticles for the oxidation of morin.  NEW JOURNAL OF CHEMISTRY,  43  (22): (8774-8780).  [PMID:] [10.1039/C9NJ00887J]
15. Meihui Fan, Huafang Ding, Guowen Zhang, Xing Hu, Deming Gong.  (2019)  Relationships of dietary flavonoid structure with its tyrosinase inhibitory activity and affinity.  LWT-FOOD SCIENCE AND TECHNOLOGY,  107  (25).  [PMID:] [10.1016/j.lwt.2019.02.076]
16. Longgang Wang, Jin Zhang, Xiaolei Guo, Shengfu Chen, Yanshuai Cui, Qingyu Yu, Lubin Yang, Haotian Sun, Dawei Gao, Danyang Xie.  (2018)  Highly stable and biocompatible zwitterionic dendrimer-encapsulated palladium nanoparticles that maintain their catalytic activity in bacterial solution.  NEW JOURNAL OF CHEMISTRY,  42  (24): (19740-19748).  [PMID:] [10.1039/C8NJ04263B]
17. Wang Qianqian, Xu Yixiang, Xu Jiaqi, Wang Xudong, Shen Chen, Zhang Yan, Liu Xiufeng, Yu Boyang, Zhang Jian.  (2017)  Molecular cloning and expression of a glycosyltransferase from Bacillus subtilis for modification of morin and related polyphenols.  BIOTECHNOLOGY LETTERS,  39  (8): (1229-1235).  [PMID:28484911] [10.1007/s10529-017-2352-z]
18. Yang Huang, Ying Feng, Guangyun Tang, Minyi Li, Tingting Zhang, Marianne Fillet, Jacques Crommen, Zhengjin Jiang.  (2017)  Development and validation of a fast SFC method for the analysis of flavonoids in plant extracts.  JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,  140  (384).  [PMID:28347593] [10.1016/j.jpba.2017.03.012]
19. Shuzhen Yang, Jie Zhou, Dongmei Li, Chunyu Shang, Litao Peng, Siyi Pan.  (2017)  The structure-antifungal activity relationship of 5,7-dihydroxyflavonoids against Penicillium italicum.  FOOD CHEMISTRY,  224  (26).  [PMID:28159264] [10.1016/j.foodchem.2016.12.001]
20. Depeng Kong, Fanyong Yan, Yunmei Luo, Qianghua Ye, Siyushan Zhou, Li Chen.  (2017)  Amphiphilic carbon dots for sensitive detection, intracellular imaging of Al3+.  ANALYTICA CHIMICA ACTA,  953  (63).  [PMID:28010744] [10.1016/j.aca.2016.11.049]
21. Li Zeng, Guowen Zhang, Yijing Liao, Deming Gong.  (2016)  Inhibitory mechanism of morin on α-glucosidase and its anti-glycation properties.  Food & Function,  (9): (3953-3963).  [PMID:27549567] [10.1039/C6FO00680A]
22. Suyun Lin, Guowen Zhang, Yijing Liao, Junhui Pan, Deming Gong.  (2015)  Dietary Flavonoids as Xanthine Oxidase Inhibitors: Structure–Affinity and Structure–Activity Relationships.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,  63  (35): (7784–7794).  [PMID:26285120] [10.1021/acs.jafc.5b03386]
23. Xiaodan Liu, Xia Wu.  (2014)  Fluorescence enhancement of fisetin by silver nanoparticles with cetyltrimethyl ammonium bromide micelles.  RSC Advances,  (10): (7433-7439).  [PMID:] [10.1039/C4RA12726A]
24. Bowen Xiao, Huijuan Wang, Xijuan Zhao, Yuanfang Li.  (2014)  Selective recognition of luteolin and quercetin based on the specific interaction of ortho-dihydroxy substituents with a zinc(II) complex.  Analytical Methods,  (9): (2894-2899).  [PMID:] [10.1039/C4AY00066H]

Solution Calculators