| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| A423552-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $69.90 |
ALDH2 activator; cardioprotective
| Synonyms | CHEBI:94988 | SCHEMBL503808 | Alda 1 | Benzamide, N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichloro- | N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide | DTXSID801324445 | C74792 | HMS2847P05 | ALDH2 Agonist, Alda-1 | SMR000518092 | Alda1 | Alda-1 | Q271667 |
|---|---|
| Specifications & Purity | 10mM in DMSO |
| Biochemical and Physiological Mechanisms | Activator of aldehyde dehydrogenase 2 (ALDH2). Increases activity of wild-type ALDH2*1 and variant ALDH2*2 (by ~2-fold and 11-fold respectively). Capable of partly restoring mutant ALDH2*2 activity; protective against cardiac ischemia. |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| IUPAC Name | N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide |
|---|---|
| INCHI | InChI=1S/C15H11Cl2NO3/c16-10-2-1-3-11(17)14(10)15(19)18-7-9-4-5-12-13(6-9)21-8-20-12/h1-6H,7-8H2,(H,18,19) |
| InChi Key | NMKJFZCBCIUYHI-UHFFFAOYSA-N |
| Canonical SMILES | C1OC2=C(O1)C=C(C=C2)CNC(=O)C3=C(C=CC=C3Cl)Cl |
| Isomeric SMILES | C1OC2=C(O1)C=C(C=C2)CNC(=O)C3=C(C=CC=C3Cl)Cl |
| WGK Germany | 3 |
| PubChem CID | 831629 |
| Molecular Weight | 324.16 |
| Pictogram(s) | GHS06, GHS09 |
|---|---|
| Signal | Danger |
| Hazard Statements | H301:Toxic if swallowed H400:Very toxic to aquatic life |
| Precautionary Statements | P273:Avoid release to the environment. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P391:Collect spillage. P330:Rinse mouth. P301+P316:IF SWALLOWED: Get emergency medical help immediately. |
| WGK Germany | 3 |
| RIDADR | UN28116.1/PGIII |
