Adenosine 5′-diphosphate sodium salt - 10mM in Water, high purity , CAS No.20398-34-9

  • 10mM in Water
Item Number
A422480
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SKUSizeAvailabilityPrice Qty
A422480-1ml
1ml
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$234.90
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Basic Description

Synonyms20398-34-9 | Adenosine 5'-diphosphate sodium salt | Adenosine-5'-diphosphate trisodium salt | ADP Sodium Salt | Sodium ((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl diphosphate | ADP Sodium | 2092-65-1 | trisodium;[[(2R,3S,4R,5R)-5-(
Specifications & Purity10mM in Water
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Product Description

Adenosine 5′-diphosphate (ADP) is an adenine nucleotide involved in energy storage and nucleic acid metabolism via its conversion into ATP by ATP synthases. ADP affects platelet activation through its interaction with ADP receptors P2Y1, P2Y12 and P2X1. Upon its conversion to adenosine by ecto-ADPases, platelet activation is inhibited via adenosine receptors.

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Names and Identifiers

IUPAC Name trisodium;[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] phosphate
INCHI InChI=1S/C10H15N5O10P2.3Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20);;;/q;3*+1/p-3/t4-,6-,7-,10-;;;/m1.../s1
InChi Key KWEUUBDPVVHQAL-MSQVLRTGSA-K
Canonical SMILES [Na].Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)OP(O)(O)=O)C(O)C3O
Isomeric SMILES C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)([O-])OP(=O)([O-])[O-])O)O)N.[Na+].[Na+].[Na+]
PubChem CID 12797869
Molecular Weight 427.20(free)

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

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Citations of This Product

1. Yihao Liu, Haoyi Niu, Chengwei Wang, Xiaoxiao Yang, Wentao Li, Yuxin Zhang, Xiaojun Ma, Yuanjing Xu, Pengfei Zheng, Jinwu Wang, Kerong Dai.  (2022)  Bio-inspired, bio-degradable adenosine 5′-diphosphate-modified hyaluronic acid coordinated hydrophobic undecanal-modified chitosan for hemostasis and wound healing.  Bioactive Materials,  17  (162).  [PMID:35386451] [10.1016/j.bioactmat.2022.01.025]
2. Shi Zhe Du, Zhe Sun, Lei Han, Min Qing, Hong Qun Luo, Nian Bing Li.  (2020)  Two 3d-4f metal-organic frameworks as fluorescent sensor array for the discrimination of phosphates based on different response patterns.  SENSORS AND ACTUATORS B-CHEMICAL,  324  (128757).  [PMID:] [10.1016/j.snb.2020.128757]
3. Xiaofang Jiang, Jing Hu, Yajun Zhang, Xiaoliang Zeng, Zhou Long.  (2020)  Fast synthesis of bimetallic metal-organic frameworks based on dielectric barrier discharge for analytical atomic spectrometry and ratiometric fluorescent sensing.  MICROCHEMICAL JOURNAL,  159  (105417).  [PMID:] [10.1016/j.microc.2020.105417]
4. Xiaoyu Wang, Xiaoqian Jiang, Hui Wei.  (2020)  Phosphate-responsive 2D-metal–organic-framework-nanozymes for colorimetric detection of alkaline phosphatase.  Journal of Materials Chemistry B,  (31): (6905-6911).  [PMID:32424386] [10.1039/C9TB02542A]
5. Li Qin, Xiaoyu Wang, Yufeng Liu, Hui Wei.  (2018)  2D-Metal–Organic-Framework-Nanozyme Sensor Arrays for Probing Phosphates and Their Enzymatic Hydrolysis.  ANALYTICAL CHEMISTRY,  90  (16): (9983–9989).  [PMID:30044077] [10.1021/acs.analchem.8b02428]
6. Kong D, Xue T, Guo B, Cheng J, Liu S, Wei J, Lu Z, Liu H, Gong G, Lan T et al..  (2019)  Optimization of P2Y12 Antagonist Ethyl 6-(4-((Benzylsulfonyl)carbamoyl)piperidin-1-yl)-5-cyano-2-methylnicotinate (AZD1283) Led to the Discovery of an Oral Antiplatelet Agent with Improved Druglike Properties..  J Med Chem,  62  (6): (3088-3106).  [PMID:30843696] [10.1021/op500134e]

References

1. Yihao Liu, Haoyi Niu, Chengwei Wang, Xiaoxiao Yang, Wentao Li, Yuxin Zhang, Xiaojun Ma, Yuanjing Xu, Pengfei Zheng, Jinwu Wang, Kerong Dai.  (2022)  Bio-inspired, bio-degradable adenosine 5′-diphosphate-modified hyaluronic acid coordinated hydrophobic undecanal-modified chitosan for hemostasis and wound healing.  Bioactive Materials,  17  (162).  [PMID:35386451] [10.1016/j.bioactmat.2022.01.025]
2. Shi Zhe Du, Zhe Sun, Lei Han, Min Qing, Hong Qun Luo, Nian Bing Li.  (2020)  Two 3d-4f metal-organic frameworks as fluorescent sensor array for the discrimination of phosphates based on different response patterns.  SENSORS AND ACTUATORS B-CHEMICAL,  324  (128757).  [PMID:] [10.1016/j.snb.2020.128757]
3. Xiaofang Jiang, Jing Hu, Yajun Zhang, Xiaoliang Zeng, Zhou Long.  (2020)  Fast synthesis of bimetallic metal-organic frameworks based on dielectric barrier discharge for analytical atomic spectrometry and ratiometric fluorescent sensing.  MICROCHEMICAL JOURNAL,  159  (105417).  [PMID:] [10.1016/j.microc.2020.105417]
4. Xiaoyu Wang, Xiaoqian Jiang, Hui Wei.  (2020)  Phosphate-responsive 2D-metal–organic-framework-nanozymes for colorimetric detection of alkaline phosphatase.  Journal of Materials Chemistry B,  (31): (6905-6911).  [PMID:32424386] [10.1039/C9TB02542A]
5. Li Qin, Xiaoyu Wang, Yufeng Liu, Hui Wei.  (2018)  2D-Metal–Organic-Framework-Nanozyme Sensor Arrays for Probing Phosphates and Their Enzymatic Hydrolysis.  ANALYTICAL CHEMISTRY,  90  (16): (9983–9989).  [PMID:30044077] [10.1021/acs.analchem.8b02428]
6. Kong D, Xue T, Guo B, Cheng J, Liu S, Wei J, Lu Z, Liu H, Gong G, Lan T et al..  (2019)  Optimization of P2Y12 Antagonist Ethyl 6-(4-((Benzylsulfonyl)carbamoyl)piperidin-1-yl)-5-cyano-2-methylnicotinate (AZD1283) Led to the Discovery of an Oral Antiplatelet Agent with Improved Druglike Properties..  J Med Chem,  62  (6): (3088-3106).  [PMID:30843696] [10.1021/op500134e]

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